Heavy Ion Therapy Research Integration plus

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

All governance boards installed

The General Assembly (GA), the Technical Project board (TPB), the External Scientific Advisory Board (ESAB), the Advisory Board for Ethical, Legal, Industrial Issues (ABELII), the Central Project Office (CPO) and the User Selection Panel (USP) will be proposed and approved

HITRIplus delivers 100 hrs of research TNA by month 18

HITRIplus delivers 100 hrs of research TNA by month 18. Treatment of 10 patients with heavy ion therapy in TA by month 18

Review of promising innovative heavy ion therapy approaches to be brought to the clinics and Trial protocol for innovative heavy ion therapy concept

Review of promising innovative heavy ion therapy approaches to be brought to the clinics

Conceptual Design Report for a patient chair capable of rotating the patient around a vertical axis as well as a vertical in-room imaging system

From market and literature research, recommendations and specifications are assembled into a CDR on vertical patient positioning and imaging. The CDR should support a later procurement of a patient system in a clinical center. The design of the SEEIIST facility will be taken as a baseline environment.

Value propositions

Promotional text and visual material aimed at describing the added value of HITRIplus technologies for companies

Magnet Assessment for SC accelerator and gantry

Report on assessment of magnet types, suitable for fast SC synchrotron and for SC gantry and preliminary evaluation

Data Management Plan

The data management plan describing the data management life cycle for the data to be collected, processed and/or generated within HITRIplus project will be defined.In addition, concerning the use of personal data, this deliverable will report: how all of the data they intend to process is relevant and limited to the purposes of the research project (in accordance with the ‘data minimisation ‘principle);a description of the technical and organisational measures that will be implemented to safeguard the rights and freedoms of the data subjects/research participants; a description of the security measures that will be implemented to prevent unauthorised access to personal data or the equipment used for processing;description of the anonymysation/pseudonymisation techniques that will be implemented.Detailed information on the informed consent procedures in regard to data processing must and templates of the informed consent forms and information sheets (in language and terms intelligible to the participants) will be kept on file and made available upon request.

Dissemination to the community about the possibility of the TA and access to clinical research with patients from EU - through out

Inform medical and research communities about the existence and actions of Transnational Access and contribute to create awareness on heavy ion therapy through a dynamic and interactive website.Promote awareness and understanding of heavy ion therapy needs of particle therapy in the community at large, by organizing events: talks, lectures, webinars, workshops, outreach via social networks . An institutional video, adaptable to the different communication methods, wil be an effective tool

Delivery of specialised training courses

Delivery of two one-week training courses on heavy ion therapy research by specialists in the field. The delivery date assigned will comprise the reports collected in the various intervals mentioned in the submitted file.

Provision of e-learning courses

Conversion of the training courses and masterclasses into e-learning courses. The delivery date assigned will comprise the reports collected in the various intervals mentioned in the submitted file.

Organisation of secondments and internships: calendar of events

Organisation of secondments and internships in current heavy ion therapy research infrastructures. The delivery date assigned will comprise the reports collected in the various intervals mentioned in the submitted file.

Design study on novel treatment room control systems

Design novel treatment control system, which will increase patient safety, increase treatment quality, lower the total treatment time, and ensure easy operation and smooth clinical workflows.

Particle arc therapy delivery to a small scale demonstrator of a rotational patient positioning system for gantry-free delivery with a position feedback integrated to the DDS

Using the demonstrator from M9.1, a particle arc therapy plan is delivered to a mouse-like phantom, to perform technical evaluation as well as assess dosimetric benefits in comparison to conventional fields.

Pubblicazioni

FLASH with carbon ions: Tumor control, normal tissue sparing, and distal metastasis in a mouse osteosarcoma model

Autori: Walter Tinganelli, Uli Weber, Anggraeini Puspitasari, Palma Simoniello, Amir Abdollahi, Julius Oppermann, Christoph Schuy, Felix Horst, Alexander Helm, Claudia Fournier, Marco Durante
Pubblicato in: Radiotherapy and Oncology, Numero 01678140, 2022, Pagina/e 185-190, ISSN 0167-8140
Editore: Elsevier BV
DOI: 10.1016/j.radonc.2022.05.003

Head and neck cancers: reporting indications and results of hadrontherapy of a dual beam facility

Autori: Barbara Vischioni, Maria Bonora, Sara Ronchi, Rossana Ingargiola, Anna Maria Camarda, Sara Lillo, Eleonora Rossi, Mattia Pecorilla, Stefania Russo, Alfredo Mirandola, Sara Imparato, Silvia Molinelli & Ester Orlandi
Pubblicato in: Health and Technology, 2024, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00843-w

Towards multiple energy extraction operation in ion beam therapy

Autori: R. Steinbrügge, T. Haberer, A. Peters, C. Schoemers
Pubblicato in: JACoW IPAC, 2023, ISSN 2673-5490
Editore: JACoW
DOI: 10.18429/jacow-ipac2023-thpm063

Opportunities and challenges of upright patient positioning in radiotherapy

Autori: Lennart Volz, James Korte, Maria Chiara Martire, Ye Zhang, Nicholas Hardcastle, Marco Durante, Tomas Kron, Christian Graeff
Pubblicato in: Physics in Medicine & Biology, Numero 69, 2024, Pagina/e 18TR02, ISSN 0031-9155
Editore: Institute of Physics Publishing
DOI: 10.1088/1361-6560/ad70ee

Emerging technologies for cancer therapy using accelerated particles

Autori: Christian Graeff, Lennart Volz, Marco Durante
Pubblicato in: Prog Part Nucl Phys., 2023, ISSN 0146-6410
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.ppnp.2023.104046

European projects join forces to investigate the next generation of ion therapy magnets

Autori: E. De Matteis
Pubblicato in: Accelerating News, Numero 39, 2022, ISSN 2296-6536
Editore: CERN

First experimental test of a coded-mask gamma camera for proton therapy monitoring

Autori: Magdalena Kołodziej, Stephan Brons, Mikołaj Dubiel, George N Farah, Alexander Fenger, Ronja Hetzel, Jonas Kasper, Monika Kercz, Barbara Kołodziej, Linn Mielke, Gabriel Ostrzołek, Magdalena Rafecas, Jorge Roser, Katarzyna Rusiecka, Achim Stahl, Vitalii Urbanevych, Ming-Liang Wong, Aleksandra Wrońska
Pubblicato in: Physics in Medicine & Biology, Numero 70, 2025, Pagina/e 115017, ISSN 0031-9155
Editore: Institute of Physics Publishing
DOI: 10.1088/1361-6560/adc96b

Slow extraction modelling for NIMMS hadron therapy synchrotrons

Autori: R Taylor, E Benedetto, M Sapinski, J Pasternak
Pubblicato in: Journal of Physics: Conference Series, Numero 2420, 2023, Pagina/e 012101, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/2420/1/012101

Magnet Technology and Design of Superconducting Magnets for Heavy Ion Gantry for Hadron Therapy

Autori: L. Rossi, D. Barna, A. G. Carloni, E. De Matteis, S. Farinon, E. Felcini, E. Gautheron, M. Karppinen, G. Kirby, T. Lecrevisse, R. Musenich, D. Perini, M. Prioli, M. Pullia, S. Sorti and D. Tommasini
Pubblicato in: Journal of Physics: Conference Series, 2024, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/2687/9/092009

Gantries for carbon ions

Autori: M. G. Pullia, E. Felcini, E. Benedetto, L. Dassa, E. De Matteis, M. Donetti, G. Frisella, M. Karppinen, C. Kurfurst, S. Mariotto, A. Mereghetti, A. Mirandola, A. Pella, D. Perini, L. Piacentini, M. T. F. Pivi, M. Prioli, A. Ratkus, L. Rossi, L. Sabbatini, S. Savazzi, M. Stock, T. Torims, S. Uberti, R. Valente, A. Vannozzi & M. Vretenar
Pubblicato in: Health and Technology, 2024, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00870-7

Carbon minibeam radiation therapy results in tumor growth delay in an osteosarcoma murine model

Autori: Annaïg Bertho, Christian Graeff, Ramon Ortiz, Maria Giorgi, Christoph Schuy, Marjorie Juchaux, Cristèle Gilbert, Julie Espenon, Julius Oppermann, Olga Sokol, Walter Tinganelli, Yolanda Prezado
Pubblicato in: Scientific Reports, Numero 15, 2025, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-025-91872-6

Diamond based integrated detection system for dosimetric and microdosimetric characterization of radiotherapy ion beams

Autori: Claudio Verona, Sandra Barna, Dietmar Georg, Yasmin Hamad, Giulio Magrin, Marco Marinelli, Cynthia Meouchi, Gianluca Verona Rinati
Pubblicato in: Medical Physics, 2023, ISSN 0094-2405
Editore: American Association of Physicists in Medicine
DOI: 10.1002/mp.16698

Straight and Curved Canted Cosine Theta Superconducting Dipoles for Ion Therapy: Comparison Between Various Design Options and Technologies for Ramping Operation

Autori: Matteis, E De; Barna, D; Ceruti, G; Kirby, G ; Lecrevisse, T; Mariotto, S; Perini, D; Prioli, M; Rossi, L; Scibor, K; Statera, M ; Sorbi, M; Sorti, S; Toral, F ; Valente, R
Pubblicato in: IEEE Transactions on Applied Superconductivity, 2023, ISSN 1051-8223
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tasc.2023.3259330

Beam optics studies for a novel gantry for hadron therapy

Autori: E Felcini, G Frisella, A Mereghetti, M G Pullia, S Savazzi, M T F Pivi, E Benedetto
Pubblicato in: Journal of Physics: Conference Series, Numero 2420, 2023, Pagina/e 012098, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/2420/1/012098

Deep learning-based voxel sampling for particle therapy treatment planning

Autori: A Quarz, L Volz, C Hoog Antink, M Durante, C Graeff
Pubblicato in: Physics in Medicine & Biology, Numero 69, 2024, Pagina/e 155014, ISSN 0031-9155
Editore: Institute of Physics Publishing
DOI: 10.1088/1361-6560/ad5bba

Physics and biomedical challenges of cancer therapy with accelerated heavy ions

Autori: Marco Durante, Jürgen Debus, Jay S. Loeffler
Pubblicato in: Nature Reviews Physics, 2021, ISSN 2522-5820
Editore: Springer Nature
DOI: 10.1038/s42254-021-00368-5

A New Algorithm for Optimizing the Field Quality of Curved CCT Magnets

Autori: Dora Veres; Tamas Vaszary; Elena Benedetto; Daniel Barna
Pubblicato in: Crossref, Numero 10518223, 2022, ISSN 1051-8223
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tasc.2022.3162389

Hadron Therapy Achievements and Challenges: The CNAO Experience

Autori: Sandro Rossi
Pubblicato in: Physics, Numero 26248174, 2022, Pagina/e 229-257, ISSN 2624-8174
Editore: MDPI
DOI: 10.3390/physics4010017

ENLIGHT (European Network for Light Ion Hadron Therapy) and its role in Hadron therapy

Autori: Petya Georgieva & Manjit Dosanjh
Pubblicato in: Health and Technology, 2024, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00837-8

Explorative Studies of an Innovative Superconducting Gantry

Autori: Pullia, M.G.; Donetti, M.; Felcini, E.; Frisella, G.; Mereghetti, A.; Mirandola, A.; Pella, A.; Savazzi, S.; Dassa, L.; Karppinen, M.; Perini, D.; Tommasini, D.; Vretenar, M.; Kürfürst, C.; Pivi, M.T.F.; Stock, M.; De Matteis, E.; Mariotto, S.; Prioli, M.; Rossi, L.; Sabbatini, L.; Vannozzi, A.; Piacentini, L.; Ratkus, A.; Torims, T.; Vilcans, J.; Benedetto, E.; Uberti, S.
Pubblicato in: Journals of Accelerator Conferences Website, Numero 8, 2022, Pagina/e 2966-2969, ISSN 2673-5490
Editore: JACoW Publishing
DOI: 10.18429/JACoW-IPAC2022-THPOMS012

A generative adversarial network to improve integrated mode proton imaging resolution using paired proton–carbon data

Autori: Mikaël Simard, Ryan Fullarton, Lennart Volz, Christoph Schuy, Savanna Chung, Colin Baker, Christian Graeff, Charles‐Antoine Collins Fekete
Pubblicato in: Medical Physics, Numero 52, 2025, ISSN 0094-2405
Editore: American Association of Physicists in Medicine
DOI: 10.1002/mp.18081

Carbon Ion Dose Constraints in the Head and Neck and Skull Base: Review of MedAustron Institutional Protocols

Autori: Piero Fossati, Ana Perpar, Markus Stock, Petra Georg, Antonio Carlino, Joanna Gora, Giovanna Martino, Eugen B. Hug
Pubblicato in: International Journal of Particle Therapy, Numero 8, 2025, Pagina/e 25-35, ISSN 2331-5180
Editore: Elsevier BV
DOI: 10.14338/ijpt-20-00093.1

Investigating Slit-Collimator-Produced Carbon Ion Minibeams with High-Resolution CMOS Sensors

Autori: Volz L, Reidel C-A, Durante M, Prezado Y, Schuy C, Weber U, Graeff C
Pubblicato in: Instruments, 2023, ISSN 2410-390X
Editore: MDPI AG

Minimizing Disturbance in Ion Beam Profiling with PEPITES Monitor

Autori: A. Esper, L. Bernardi, M. Donetti, R. Duhamel, F. Gastaldi, O. Gevin, R. Guillaumat, M. Pullia, C. Thiebaux, M. Verderi, C. Viviani
Pubblicato in: Journal of Physics: Conference Series, Numero 3094, 2025, Pagina/e 012043, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/3094/1/012043

A compact synchrotron for advanced cancer therapy with helium and proton beams

Autori: M Vretenar, M E Angolettai, G Bisoffi, J Borburgh, L Bottura, K Paļskis, R Taylor, G Tranquille, E Benedetto, M Sapinski
Pubblicato in: Journal of Physics: Conference Series, Numero 2420, 2023, Pagina/e 012103, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/2420/1/012103

THE HITRIPLUS PROJECT – NETWORKING AND COMMUNICATION, DISSEMINATION AND OUTREACH

Autori: Peter Grübling, Manjit Dosanjh, Petya Georgieva, Silvia Meneghello, Nicholas Sammut
Pubblicato in: International Journal of Particle Therapy, Numero 17, 2025, Pagina/e 101134, ISSN 2331-5180
Editore: Elsevier BV
DOI: 10.1016/j.ijpt.2025.101134

Considerations for Upright Particle Therapy Patient Positioning and Associated Image Guidance

Autori: Lennart Volz, Yinxiangzi Sheng, Marco Durante, Christian Graeff
Pubblicato in: Frontiers in Oncology, Numero 2234943X, 2022, ISSN 2234-943X
Editore: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.930850

“Particle therapy - future for the Baltic states?” – synthesis of the expert workshop report

Autori: Kristaps Paļskis, Erika Korobeinikova, Dace Bogorada-Saukuma, Anna Maria Camarda, Rebecca Taylor, Elena Benedetto, Edgars Mamis, Maija Radziņa, Andrejs Ērglis, Diana Adliene, Manjit Dosanjh, Maurizio Vretenar, Toms Torims
Pubblicato in: Health and Technology, Numero 14, 2024, Pagina/e 965-972, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00875-2

Experimental characterisation and comparison of two Si-based compactsetups for proton imaging of small animals for image-guided proton irradiation

Autori: Guyue Hu, Angelica Noto , Katrin Schnurle , Matthias Wurl, Franz Siegfried Englbrecht , Johannes Gebhard, Jonathan Bortfeldt, Mateusz Sitarz , Per Poulsen , Katia Parodi
Pubblicato in: Proceedings to the 61st Annual Conference of the Particle Therapy Cooperative Group, 2023, ISSN 2331-5180
Editore: Elsevier
DOI: 10.14338/ijpt-23-ptcog61-10.2.

Investigating Slit-Collimator-Produced Carbon Ion Minibeams with High-Resolution CMOS Sensors

Autori: Lennart Volz, Claire-Anne Reidel, Marco Durante, Yolanda Prezado, Christoph Schuy, Uli Weber, Christian Graeff
Pubblicato in: Instruments, Numero 7, 2025, Pagina/e 18, ISSN 2410-390X
Editore: MDPI AG
DOI: 10.3390/instruments7020018

The Superconducting Shield (SuShi) Septum Magnet Prototype

Autori: D. Barna; J. Borburgh; M. Atanasov; G. Kirby; G. Giunchi; V. Karpati; M. Szucs; G. Szabo; V. Mertinger
Pubblicato in: Crossref, Numero 10518223, 2022, ISSN 1051-8223
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tasc.2022.3149726

Treatment Planning: comparing techniques and standards

Autori: Silvia Molinelli, Alfredo Mirandola, Giuseppe Magro, Stefania Russo, Alessandro Vai, Eleonora Rossi, Alessia Bazani, Luca Trombetta, Matteo Bagnalasta, Ester Orlandi & Mario Ciocca
Pubblicato in: Health and Technology, 2024, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00845-8

New technologies: superconducting magnets

Autori: Ernesto De Matteis
Pubblicato in: Health and Technology, 2024, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00849-4

Monte Carlo simulation model of the SIRMIO beamline and experimentalvalidation in clinical facilities

Autori: Ze Huang, Jonathan Bortfeldt, Neeraj Kurichiyanil, Katrin Schnurle , Franz S. Englbrecht, Thomas Rosch, Sairos Safai , Mateusz Sitarz , Katia Parodi, Marco Pinto
Pubblicato in: Proceedings to the 61st Annual Conference of the Particle Therapy Cooperative Group, 2023, Pagina/e 289, ISSN 2331-5180
Editore: Elsevier
DOI: 10.14338/ijpt-23-ptcog61-10.2

Long-Term Tumor Control After Carbon Ion Radiation Therapy Boost in Locally Advanced Cervical Clear Cell Adenocarcinoma

Autori: Amelia Barcellini, Alessandro Vai, Eloisa Arbustini, Marco Carnelli, Sara Imparato, Durim Delishaj, Carlo Pietro Soatti, Carmine Tinelli, Elisabetta Vitali, Viviana Vitolo, Ester Orlandi
Pubblicato in: International Journal of Particle Therapy, Numero 17, 2026, Pagina/e 101200, ISSN 2331-5180
Editore: Elsevier BV
DOI: 10.1016/j.ijpt.2025.101200

Calibration of a Δ <i>E-E</i> telescope based on CeBr <sub>3</sub> scintillator for secondary charged particles measurements in hadron therapy

Autori: L. Gesson, J. Gross, C. Mozzi, C. Reibel, Ch. Finck, S. Higueret, T.D. Lê, E. Traykov, J.C. Thomas, N. Arbor, M. Pullia, G. Harmant, M. Vanstalle
Pubblicato in: Journal of Instrumentation, Numero 21, 2026, Pagina/e P01037, ISSN 1748-0221
Editore: Institute of Physics
DOI: 10.1088/1748-0221/21/01/p01037

Imaging lung tumor motion using integrated‐mode proton radiography—A phantom study towards tumor tracking in proton radiotherapy

Autori: Ryan Fullarton, Mikaël Simard, Lennart Volz, Allison Toltz, Savanna Chung, Christoph Schuy, Daniel G. Robertson, Gary Royle, Sam Beddar, Colin Baker, Christian Graeff, Charles‐Antoine Collins‐Fekete
Pubblicato in: Medical Physics, Numero 52, 2025, Pagina/e 1146-1158, ISSN 0094-2405
Editore: American Association of Physicists in Medicine
DOI: 10.1002/mp.17508

Comparison of 352 MHz linac structures for injection into an ion therapy accelerator

Autori: L. Nikitovic , T. Torims and M. Vretenar
Pubblicato in: 10.1088/1742-6596/2687/5/052011, 2024, ISSN 1742-6588
Editore: Institute of Physics

Status of Nb-Ti CCT Magnet EU Programs for Hadron Therapy

Autori: F Toral, F. D Barna, C Calzolaio, A Carloni, G Ceruti, E De Matteis, G Kirby, T Lecrevisse, S Mariotto, J Munilla, D Perini, M Prioli, L Rossi, M Statera, M Sorbi, S Sorti, RU Valente
Pubblicato in: IEEE Transactions on Applied Superconductivity, 2024, ISSN 1051-8223
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tasc.2023.3349252

Focus stacking single-event particle radiography for high spatial resolution images and 3D feature localization

Autori: Lennart Volz , Christian Graeff , Marco Durante , Charles-Antoine Collins-Fekete
Pubblicato in: Physics in Medicine & Biology, 2024, ISSN 0031-9155
Editore: Institute of Physics Publishing
DOI: 10.1088/1361-6560/ad131a

HyperSHArc: Single-Isocenter Stereotactic Radiosurgery of Multiple Brain Metastases Using Proton, Helium, and Carbon Ion Arc Therapy

Autori: Lennart Volz, Peilin Liu, Thomas Tessonnier, Xiaoda Cong, Marco Durante, Andrea Mairani, Wenbo Gu, Amir Abdollahi, Xuanfeng Ding, Christian Graeff, Taoran Li, Stewart Mein
Pubblicato in: Advances in Radiation Oncology, Numero 10, 2025, Pagina/e 101763, ISSN 2452-1094
Editore: Elsevier BV
DOI: 10.1016/j.adro.2025.101763

Organization and operation of multi particle therapy facilities: the Marburg Ion-Beam Therapy Center, Germany (MIT)

Autori: Klemens Zink, Kilian Simon Baumann, Ulrike Theiss, Florentine Subtil, Sonja Lahrmann, Fabian Eberle, Sebastian Adeberg
Pubblicato in: Health and Technology, Numero 14, 2024, Pagina/e 929-938, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00881-4

The Heavy Ions Therapy Research Integration plus project

Autori: Facoetti A, Rossi S.
Pubblicato in: Health and Technology, 2024, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00841-y

Exploring energy selection methods for robust biologically optimized carbon ion arc for head&neck cancer patients

Autori: Lennart Volz, Yinxiangzi Sheng, Lin Kong, Marco Durante, Christian Graeff
Pubblicato in: Health and Technology, Numero 14, 2024, Pagina/e 873-888, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00877-0

Production of 11C, 13N and 15O in proton-induced nuclear reactions up to 200 MeV

Autori: T. Rodríguez-González, C. Guerrero, C.M. Bäcker, J. Bauer, C. Bäumer, S. Brons, W. Jentzen, M.C. Jiménez-Ramos, M.Á. Millán-Callado, C. Schömers, B. Timmermann, J.M. Quesada, R. Capote
Pubblicato in: Nuclear Data Sheets, Numero 187, 2025, Pagina/e 579-596, ISSN 0090-3752
Editore: Academic Press
DOI: 10.1016/j.nds.2023.01.004

Explorative studies of an innovative superconducting gantry

Autori: M G Pullia, E Benedetto, L Dassa, E De Matteis, M Donetti, E Felcini, G Frisella, M Karppinen, C Kurfürst, S Mariotto
Pubblicato in: Journal of Physics: Conference Series, 2024, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/2420/1/012099

Radiation quality matters: morphological and biochemical responses of Brassica rapa microgreens to X-rays, C-ions, and Fe-ions

Autori: Sara De Francesco, Chiara Amitrano, Ermenegilda Vitale, Giulia Costanzo, Walter Tinganelli, Mariagabriella Pugliese, Cecilia Arrichiello, Paolo Muto, Marco Durante, Stefania De Pascale, Carmen Arena, Veronica De Micco
Pubblicato in: Planta, Numero 262, 2025, ISSN 0032-0935
Editore: Springer Verlag
DOI: 10.1007/s00425-025-04835-6

TIARA: a fast gamma-ray detector for range monitoring in Proton Therapy

Autori: A. André, M. Pinson, C. Hoarau, Y. Boursier, M. Dupont, L. Gallin Martel, M.-L. Gallin Martel, A. Garnier, J. Hérault, J.-P. Hofverberg, P. Kavrigin, C. Morel, J.-F. Muraz, M. Pullia, S. Savazzi, D. Maneval, S. Marcatili
Pubblicato in: IEEE Transactions on Radiation and Plasma Medical Sciences, 2026, Pagina/e 1-1, ISSN 2469-7311
Editore: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.1109/trpms.2026.3659489

Evaluation of proton and carbon ion beam models in TReatment Planning for Particles 4D (TRiP4D) referring to a commercial treatment planning system

Autori: Yinxiangzi Sheng, Lennart Volz, Weiwei Wang, Marco Durante, Christian Graeff
Pubblicato in: Zeitschrift für Medizinische Physik, Numero 35, 2025, Pagina/e 218-226, ISSN 0939-3889
Editore: Urban & Fischer Verlag
DOI: 10.1016/j.zemedi.2023.06.002

Electromagnetic Losses in Fast-Ramped Canted-Cosine-Theta Magnets

Autori: Sorti, Stefano ; Ceruti, Gabriele ; De Matteis, Ernesto ; Mariotto, Samuele ; Prioli, Marco ; Rossi, Lucio ; Sorbi, Massimo ; Valente, Riccardo U.
Pubblicato in: IEEE Transactions on Applied Superconductivity, 2024, ISSN 1051-8223
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tasc.2024.3360933

SECONDARY PARTICLE EFFECTS IN PARTICLE THERAPY: EXPERIMENTAL INSIGHTS AND SIMULATED OUTCOMES

Autori: Lévana Gesson, Claire Reibel, Christian Finck, Nicolas Arbor, Stéphane Higueret, Thé-Duc Lê, Marco Pullia, Quentin Raffy, Aurélia Arnone, Philippe Peaupardin, Catherine Galindo, Marie Vanstalle
Pubblicato in: International Journal of Particle Therapy, Numero 12, 2025, Pagina/e 100457, ISSN 2331-5180
Editore: Elsevier BV
DOI: 10.1016/j.ijpt.2024.100457

Comparative Study on Scenarios for Rotating Gantry Mechanical Structures

Autori: Luca Piacentini, Luca Dassa, Diego Perini, Andris Ratkus, Toms Torims, Stefano Uberti, Janis Vilcans, Maurizio Vretenar
Pubblicato in: Open Research Europe, Numero 2, 2022, Pagina/e 55, ISSN 2732-5121
Editore: --

BNCT@CNAO: is CNAO the right place to experiment with BNCT ?

Autori: Sandro Rossi
Pubblicato in: Health and Technology, Numero 14, 2024, Pagina/e 1051-1057, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00860-9

Lumped Parameter Model for Structural Analysis of Over-Constrained Multi-Legged Parallel Mechanism Supporting System Applied to Cryogenic Devices

Autori: Luca Piacentini, Luca Dassa, Diego Perini, Andris Ratkus, Toms Torims, Stefano Uberti
Pubblicato in: Machines, Numero 13, 2025, Pagina/e 129, ISSN 2075-1702
Editore: MDPI AG
DOI: 10.3390/machines13020129

Alvarez Drift Tube Linac for Medical Applications in the Framework of Hitriplus Project

Autori: A. Mamaras, D. Sampsonidis, L. Bellan, G. Bisoffi, M. Comunian, P. A. Thonet and M. Vretenar. J
Pubblicato in: Journal of Physics: Conference Series, 2024, ISSN 1742-6588
Editore: Institute of Physics
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Training the future in HITRIplus project: A report on specialised course onheavy ion therapy research

Autori: Manjit Dosanjh, Angelica Facoetti , Maria Monica Necchi , Nicholas Sammut , Joseph Bateman, Kristaps Palskis, Taylor Rebecca, Cameron Robertson
Pubblicato in: Proceedings to the 61st Annual Conference of the Particle Therapy Cooperative Group, Numero 20, 2023, Pagina/e 335, ISSN 2331-5180
Editore: Elsevier B.V

Accelerator technologies for proton and ion beam therapy

Autori: Vivek Maradia, Benjamin Clasie, Emma Snively, Katia Parodi, Marco Schwarz, Marco Durante
Pubblicato in: Nature Physics, Numero 21, 2025, Pagina/e 1363-1373, ISSN 1745-2473
Editore: Nature Publishing Group
DOI: 10.1038/s41567-025-02994-7

Training the future in HITRIplus project: A report on specialised course onheavy ion therapy research

Autori: Manjit Dosanjh, Angelica Facoetti , Maria Monica Necchi , Nicholas Sammut , Joseph Bateman, Kristaps Palskis, Taylor Rebecca, Cameron Robertson
Pubblicato in: Proceedings to the 61st Annual Conference of the Particle Therapy Cooperative Group, 2023, Pagina/e 218, ISSN 2331-5180
Editore: Elsevier
DOI: 10.14338/ijpt-23-ptcog61-10.2

Innovations in the Next Generation Medical Accelerators for Therapy with Ion Beams

Autori: E Benedetto and M Vretenar
Pubblicato in: Journal of Physics: Conference Series, 2024, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/2687/9/092003

New accelerator designs: NIMMS

Autori: Maurizio Vretenar, Elena Benedetto
Pubblicato in: Health and Technology, Numero 14, 2024, Pagina/e 945-955, ISSN 2190-7188
Editore: Springer Verlag
DOI: 10.1007/s12553-024-00882-3

Accelerators for health: from current to dream machines

Autori: A. Faus Golfe, E. Benedetto
Pubblicato in: Europhysics News, Numero 53:3, 2022, Pagina/e 16-17, ISSN 0531-7479
Editore: European Physical Society

A European Collaboration to Investigate Superconducting Magnets for Next Generation Heavy Ion Therapy

Autori: Rossi, L. and Ballarino, A. and Barna, D. and Benedetto, E. and Calzolaio, C. and Ceruti, G. and De Matteis, E. and Echeandia, A. and Ekelof, T. and Farinon, S. and Felcini, E. and Gehring, M. and Kirby, G. and Lecrevisse, T. and Lucas, J. and Mariotto, S. and Munilla, J. and Musenich, R. and Pampaloni, A. and Pepitone, K. and Perini, D. and Popovic, D. and Prioli, M. and Pullia, M. and Quettier,
Pubblicato in: IEEE Transactions on Applied Superconductivity, Numero 32: 4, 2022, Pagina/e 1-7, ISSN 1051-8223
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tasc.2022.3147433

Performance Assessment of a Scintillator Detector for Helium Beam Fragmentation Measurements in Charged Particle Therapy

Autori: A. C. Kraan, M. Morrocchi
Pubblicato in: 2025 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD), 2025, Pagina/e 1-1
Editore: IEEE
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Slow Extraction Modelling for NIMMS Hadron Therapy Synchrotrons

Autori: Taylor, R.; Benedetto, E.; Sapinski, M.; Pasternak, J.
Pubblicato in: Journals of Accelerator Conferences Website, 2022, Pagina/e 2988-2991, ISBN 978-3-95450-227-1
Editore: JACoW Publishing
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Conceptual design of a compact synchrotron-based facility for cancer therapy and biomedical research with helium and proton beams

Autori: Vretenar, M; Angoletta, M E; Borburgh, J; Bottura, L; Taylor, R; Tranquille, G; Benedetto, E; Torims, T; Paļskis, K; Sapinski, M; Radziņa, M; Adliene, D; Korobeinikova, E; Kalniņa, M
Pubblicato in: 14th International Particle Accelerator Conference, 2023, Pagina/e 5024-5027, ISBN 978-3-95450-231-8
Editore: Journals of Accelerator Conferences Website (JACoW)
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Beam optics studies for a novel gantry for hadron therapy

Autori: Felcini, E.; Frisella, G.; Mereghetti, A; Pullia, M.G.; Savazzi, S.; Pivi, M.T.F:; Benedetto, E.
Pubblicato in: Journals of Accelerator Conferences Website, 2022, Pagina/e 2962-2965, ISBN 978-3-95450-227-1
Editore: JACoW Publishing
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Linac Design within HITRIPlus for Particle Therapy

Autori: Ratzinger, U.; Koubek, B.; Podlech, H.; Vretenar, M.
Pubblicato in: Linac2022, Liverpool, UK, 28.08-2.09.2022, Numero 5, 2022
Editore: --
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HEAVY ION THERAPY MASTERCLASS SCHOOL AND CAPACITYBUILDING FOR FUTURE ION RESEARCH AND THERAPYFACILITIES

Autori: Panagiota FOKA
Pubblicato in: International Conference on Accelerators for Research and Sustainable Development, 2023, Pagina/e 86
Editore: IAEA

Physics for health

Autori: Ralph Assmann, Darwin Caldwell, Giulio Cerullo, Henry Chapman, Dana Cialla-May, Marco Durante, Angeles Faus-Golfe, Jens Hellwage, Susanne Hellwage, Christoph Krafft, Timo Mappes, Thomas G Mayerhöfer, Thierry Mora, Andreas Peters, Chiara Poletto, Juergen Popp, Felix Ritort, Petra Rösch, Lucio Rossi, Marta Sales-Pardo, Iwan Schie, Michael Schmitt, Friedrich Simmel, Aleksandra Walczak
Pubblicato in: EPS Grand Challenges, 2025, Pagina/e 5-1-5-127
Editore: IOP Publishing
DOI: 10.1088/978-0-7503-6342-6ch5

Carbon Ion Gantry layout and optics solutions

Autori: S.Savazzi, E.Felcini, G. Frisella, A.Mereghetti, M.G.Pullia
Pubblicato in: NIMMS NOTE 007, 2022
Editore: CERN

Carbon ion compact medical synchrotron: key parameters

Autori: E. Benedetto
Pubblicato in: CERN NIMMS-Note-008, 2022
Editore: CERN

Preliminary design of SEEIIST High Energy Beam Transfer lines. M. Sapinski. May-22

Autori: M. Sapinski
Pubblicato in: NIMMS-Note- CERN-ACC-Note-, Numero 0010, 2022
Editore: CERN

IL CENTRO NAZIONALE DI ADROTERAPIA ONCOLOGICA: INNOVAZIONI TECNICO-SCIENTIFICHE E NUOVE PROSPETTIVE DELLA BNCT PER LA LOTTA AI TUMORI

Autori: Sandro Rossi, Gianluca Vago
Pubblicato in: Istituto Lombardo - Accademia di Scienze e Lettere - Rendiconti di Scienze, 2022, ISSN 2384-986X
Editore: PAGEPress Publications
DOI: 10.4081/scienze.2021.785

An Accelerator-based Research Infrastructure for Cancer Therapy and Biomedical Sciences with Ion Beams

Autori: Amaldi, Ugo; Benedetto, Elena; Foka, Panagiota; Rossi, Sandro; Vretenar, Maurizio
Pubblicato in: Numero 29, 2024
Editore: CERN

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