Neuronal microscopy for cell behavioural examination and manipulation

Leistungen

The operational procedures will be summarized in the Project Handbook a summary of procedures for management quality assurance and quality control reporting and cost follow up to all actors in the project so as to facilitate effective and efficient contribution and reporting while complying with the contractual framework and best management practices

Plans for dissemination of the results and training activities

The objective for this deliverable is to describe the dissemination strategy of the project REVEAL. For example, the dissemination strategy will rely on:•Creating the project visual identity and publishing the public dissemination materials via a dedicated project website•Designing and circulation of all templates for external communication by the partners ensuring that no patentable information is disclosed•Keeping track of all project publications and public disclosures•Informing all the partners of related events and conferences and encourage participation in the most relevant ones•Raise policy makers and scientific awareness via the use of social networks (Twitter, LinkedIn) to spread the project results into the outside worldThe firts deliverable will be delivered on M12, and an update will be provided on M24 and M36.

Murine models, cell lines and derived cells Murine models, cell lines and derived cells

Laboratory mice when subjected to environmental or nutritional challenges have been shown to develop hepatocellular carcinoma. At various stages of the disease progression, livers will be isolated, tumours will be excised and FACS sorted to isolate tumour cells for imaging and omic analysis. Cell lines and models developed at ENS Lyon will be used for training of neural networks on the prototype devices at the ENS Lyon or CEA.

Project Data Management Plan

The Data Management Plan (DMP) will describe how REVEAL will collect, process, share and protect the data produced by the project partners. The DMP will be consistent with the intellectual property right (IPR) policy (i.e., IP, confidentiality and publication provisions) to be defined in the Consortium Agreement (at the beginning of the project) and updated as any changes occur in the consortium policies.

Project website and social network account

Creating the project visual identity and publishing the public dissemination materials via a dedicated project website

Veröffentlichungen

CNN-Based Cell Analysis: From Image to Quantitative Representation

Autoren: Cédric Allier Lionel Hervé Chiara Paviolo1 Ondrej Mandula1 Olivier Cioni William Pierré1 Francesca Andriani Kiran Padmanabhan Sophie Morales
Veröffentlicht in: Frontiers in Physics, 2022, ISSN 0000-0000
Herausgeber: -
DOI: 10.3389/fphy.2021.776805

Towards true volumetric refractive index investigation in tomographic phase microscopy at the cellular level

Autoren: Maria Baczewska, Martyna Mazur, Wojciech Krauze
Veröffentlicht in: Optics Continuum, 2023, ISSN 0000-0000
Herausgeber: Optica
DOI: 10.1364/optcon.481162

Volumetric segmentation of biological cells and subcellular structures for optical diffraction tomography images

Autoren: Martyna Mazur, Wojciech Krauze
Veröffentlicht in: Biomedical Optics Express, 2023, ISSN 0000-0000
Herausgeber: Optica Publishing Group
DOI: 10.1364/boe.498275

Cell culture analysis through learning-enabled lens-free microscopy

Autoren: Florian Lemarchand, Chiara Paviolo, Lionel Hervé, Lamya Ghenim, Kiran Padmanabhan, Cédric Allier
Veröffentlicht in: HAL Open Science, 2023, ISSN 0000-0000
Herausgeber: HAL Open Science

Circulating Interlukin-32 and Altered Blood Pressure Control in Individuals with Metabolic Dysfunction

Autoren: Luca Valenti, Alessandro Cherubini
Veröffentlicht in: International Journal of Molecular Sciences, 2023, ISSN 0000-0000
Herausgeber: MDPI
DOI: 10.3390/ijms24087465

3D time-lapse imaging of a mouse embryo using intensity diffraction tomography embedded inside a deep learning framework

Autoren: William Pierré, Lionel Hervé, Chiara Paviolo, Ondrej Mandula, Vincent Remondiere, Sophie Morales, Sergei Grudinin, Pierre F. Ray, Magali Dhellemmes, Christophe Arnoult, and Cédric Allier
Veröffentlicht in: Applied Optics, 2022, ISSN 0000-0000
Herausgeber: Optica Publishing Group
DOI: 10.1364/ao.453910

Roadmap on Digital Holography-Based Quantitative Phase Imaging

Autoren: Vinoth Balasubramani, Małgorzata Kujawinska, Cédric Allier, Vijayakumar Anand, Chau-Jern Cheng, Christian Depeursinge, Nathaniel Hai, Saulius Juodkazis, Jeroen Kalkman, Arkadiusz Ku´s, Moosung Lee, Pierre J. Magistretti, Pierre Marquet, Soon Hock Ng, Joseph Rosen, Yong Keun Park, Michał Ziemczonok
Veröffentlicht in: Journal of imaging, 2021, ISSN 2313-433X
Herausgeber: MDPI
DOI: 10.3390/jimaging7120252

Estrogen–ER‐α axis induces PNPLA3 p.I148M protein variant to promote steatotic liver disease susceptibility in women

Autoren: Alessandro Cherubini, Elia Casirati, Serena Pelusi, Luca Valenti.
Veröffentlicht in: Clin Transl Med, 2024, ISSN 0000-0000
Herausgeber: National Library of Medecine
DOI: 10.1002/ctm2.1524

Prevalence and Determinants of Liver Disease in Relatives of Italian Patients With Advanced MASLD

Autoren: Serena Pelusi, Luisa Ronzoni, Jessica Rondena, Chiara Rosso, Grazia Pennisi, Paola Dongiovanni, Sara Margarita, Rossana Carpani, Giorgio Soardo, Daniele Prati, Annalisa Cespiati, Salvatore Petta, Elisabetta Bugianesi, Luca Valenti.
Veröffentlicht in: Clinical Gastroenterology and Hepatology, 2023, ISSN 0000-0000
Herausgeber: Science Direct
DOI: 10.1016/j.cgh.2023.12.033

Numerical refractive index correction for the stitching procedure in tomographic quantitative phase imaging

Autoren: Piotr Stępień, Michał Ziemczonok, Małgorzata Kujawińska, Maria Baczewska, Luca Valenti, Alessandro Cherubini, Elia Casirati, and Wojciech Krauze
Veröffentlicht in: Biomedical Optics Express, 2022, ISSN 0000-0000
Herausgeber: Optica Publishing Group
DOI: 10.1364/boe.466403

Detailed stratified GWAS analysis for severe COVID-19 in four European populations

Autoren: Luca Valenti, Alessandro Cherubini, Rossana Carpani
Veröffentlicht in: Human Molecular Genetics, 2022, ISSN 0964-6906
Herausgeber: Oxford University Press
DOI: 10.1093/hmg/ddac158

Phase unwrapping using deep learning in holographic tomography

Autoren: Michał Gontarz, Vibekananda Dutta, Małgorzata Kujawińska, Wojciech Krauze
Veröffentlicht in: Optics Express, 2023, ISSN 0000-0000
Herausgeber: Optica Publishing Group
DOI: 10.1364/oe.486984

The genetics of portal hypertension: Recent developments and the road ahead

Autoren: Sarah Shalaby, Luisa Ronzoni, Virginia Hernandez-Gea, Luca Valenti
Veröffentlicht in: Liver International, 2023, ISSN 0000-0000
Herausgeber: Wiley Online Library
DOI: 10.1111/liv.15732

Interaction between estrogen receptor-α and PNPLA3 p.I148M variant drives fatty liver disease susceptibility in women

Autoren: Alessandro Cherubini, Mahnoosh Oveis Jamialahmadi, Serena Pelusi, Eniada Rrapaj, Elia Casirati, Giulia Passignani, Marjan Norouziesfahani, Elena Sinopoli, Guido Baselli, Clara Meda, Paola Dongiovanni, Daniele Dondossola, Neil Youngson, Aikaterini Tourna, Shilpa Chokshi, Elisabetta Bugianesi, Sara Della Torre, Daniele Prati, Stefano Romeo, Luca Valenti
Veröffentlicht in: Nature Medecine, 2023, ISSN 0000-0000
Herausgeber: Nat Med
DOI: 10.1038/s41591-023-02553-8

Multiscale and multipurpose phantoms for 2D/3D quantitative phase imaging

Autoren: Michał Ziemczonok, Małgorzata Kujawińska
Veröffentlicht in: Proceedings of SPIE, 2023
Herausgeber: SPIE
DOI: 10.1117/12.2649720

Deep learning-based phase unwrapping for holographic tomography

Autoren: Michał Gontarz, Vibekananda Dutta, Małgorzata Kujawińska
Veröffentlicht in: 2023
Herausgeber: -

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