Neuronal microscopy for cell behavioural examination and manipulation

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Project handbook

The operational procedures will be summarized in the Project Handbook a summary of procedures for management quality assurance and quality control reporting and cost follow up to all actors in the project so as to facilitate effective and efficient contribution and reporting while complying with the contractual framework and best management practices

Plans for dissemination of the results and training activities

The objective for this deliverable is to describe the dissemination strategy of the project REVEAL. For example, the dissemination strategy will rely on:•Creating the project visual identity and publishing the public dissemination materials via a dedicated project website•Designing and circulation of all templates for external communication by the partners ensuring that no patentable information is disclosed•Keeping track of all project publications and public disclosures•Informing all the partners of related events and conferences and encourage participation in the most relevant ones•Raise policy makers and scientific awareness via the use of social networks (Twitter, LinkedIn) to spread the project results into the outside worldThe firts deliverable will be delivered on M12, and an update will be provided on M24 and M36.

Murine models, cell lines and derived cells Murine models, cell lines and derived cells

Laboratory mice when subjected to environmental or nutritional challenges have been shown to develop hepatocellular carcinoma. At various stages of the disease progression, livers will be isolated, tumours will be excised and FACS sorted to isolate tumour cells for imaging and omic analysis. Cell lines and models developed at ENS Lyon will be used for training of neural networks on the prototype devices at the ENS Lyon or CEA.

Project Data Management Plan

The Data Management Plan (DMP) will describe how REVEAL will collect, process, share and protect the data produced by the project partners. The DMP will be consistent with the intellectual property right (IPR) policy (i.e., IP, confidentiality and publication provisions) to be defined in the Consortium Agreement (at the beginning of the project) and updated as any changes occur in the consortium policies.

Project website and social network account

Creating the project visual identity and publishing the public dissemination materials via a dedicated project website

Pubblicazioni

Impact of PNPLA3 rs738409 Polymorphism on the Development of Liver-Related Events in Patients With Nonalcoholic Fatty Liver Disease

Autori: Chiara Rosso, Gian Paolo Caviglia, Giovanni Birolo, Angelo Armandi, Grazia Pennisi, Serena Pelusi, Ramy Younes, Antonio Liguori, Nuria Perez-Diaz-del-Campo, Aurora Nicolosi, Olivier Govaere, Gabriele Castelnuovo, Antonella Olivero, Maria Lorena Abate, Davide Giuseppe Ribaldone, Piero Fariselli, Luca Valenti, Luca Miele, Salvatore Petta, Manuel Romero-Gomez, Quentin M. Anstee, Elisabetta Bugianesi
Pubblicato in: Clinical Gastroenterology and Hepatology, Numero 21, 2023, Pagina/e 3314-3321.e3, ISSN 1542-3565
Editore: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.cgh.2023.04.024

Genetics of Metabolic Dysfunction-associated Steatotic Liver Disease: The State of the Art Update

Autori: Silvia Sookoian, Yaron Rotman, Luca Valenti
Pubblicato in: Clinical Gastroenterology and Hepatology, Numero 22, 2024, Pagina/e 2177-2187.e3, ISSN 1542-3565
Editore: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.cgh.2024.05.052

Rare ATG7 genetic variants predispose patients to severe fatty liver disease

Autori: Guido A. Baselli, Oveis Jamialahmadi, Serena Pelusi, Ester Ciociola, Francesco Malvestiti, Marco Saracino, Luigi Santoro, Alessandro Cherubini, Paola Dongiovanni, Marco Maggioni, Cristiana Bianco, Federica Tavaglione, Annalisa Cespiati, Rosellina M. Mancina, Roberta D’Ambrosio, Valentina Vaira, Salvatore Petta, Luca Miele, Umberto Vespasiani-Gentilucci, Alessandro Federico, Jussi Pihlajamaki, El
Pubblicato in: Journal of Hepatology, Numero 77, 2023, Pagina/e 596-606, ISSN 0168-8278
Editore: Elsevier BV
DOI: 10.1016/j.jhep.2022.03.031

A genetic hypothesis for burnt‐out steatohepatitis

Autori: Luca Valenti, Stefano Romeo, Utpal Pajvani
Pubblicato in: Liver International, Numero 41, 2023, Pagina/e 2816-2818, ISSN 1478-3223
Editore: Blackwell Publishing Inc.
DOI: 10.1111/liv.15103

CNN-Based Cell Analysis: From Image to Quantitative Representation

Autori: Cédric Allier Lionel Hervé Chiara Paviolo1 Ondrej Mandula1 Olivier Cioni William Pierré1 Francesca Andriani Kiran Padmanabhan Sophie Morales
Pubblicato in: Frontiers in Physics, 2022, ISSN 0000-0000
Editore: -
DOI: 10.3389/fphy.2021.776805

qtOCT: quantitative transmission optical coherence tomography

Autori: Wojciech Krauze, Martyna Mazur, Arkadiusz Kuś
Pubblicato in: preprint on arXiv, 2024, ISSN 0000-0000
Editore: Not applicable
DOI: 10.48550/arxiv.2405.14315

Towards true volumetric refractive index investigation in tomographic phase microscopy at the cellular level

Autori: Maria Baczewska, Martyna Mazur, Wojciech Krauze
Pubblicato in: Optics Continuum, 2023, ISSN 0000-0000
Editore: Optica
DOI: 10.1364/optcon.481162

He2Cl: a 2-step clustering algorithm to characterize cellular heterogeneity from cell morpho-dynamics behaviors

Autori: Alice Martin, Florian Lemarchand, Jeremy Neri, Olivier Cioni, Kiran Padmanabhan, Chiara Paviolo
Pubblicato in: TechRxiv, 2024, ISSN 0000-0000
Editore: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.36227/techrxiv.173014658.85987646/v1

Reply to: “Ceruloplasmin variants might have different effects in different iron overload disorders”

Autori: Elena Corradini, Luca V. Valenti
Pubblicato in: Journal of Hepatology, Numero 75, 2022, Pagina/e 1004-1006, ISSN 0168-8278
Editore: Elsevier BV
DOI: 10.1016/j.jhep.2021.07.007

Trends and risk factors of <scp>SARS‐CoV</scp>‐2 infection in asymptomatic blood donors

Autori: Luca Valenti, Serena Pelusi, Alessandro Cherubini, Cristiana Bianco, Luisa Ronzoni, Sara Uceda Renteria, Elena Coluccio, Alessandra Berzuini, Angela Lombardi, Leonardo Terranova, Francesco Malvestiti, Giuseppe Lamorte, Elisa Erba, Massimo Oggioni, Ferruccio Ceriotti, Daniele Prati
Pubblicato in: Transfusion, Numero 61, 2024, Pagina/e 3381-3389, ISSN 0041-1132
Editore: Blackwell Publishing Inc.
DOI: 10.1111/trf.16693

The first <scp>MASH</scp> drug therapy on the horizon: Current perspectives of resmetirom

Autori: Salvatore Petta, Giovanni Targher, Stefano Romeo, Utpal B. Pajvani, Ming‐Hua Zheng, Alessio Aghemo, Luca V. C. Valenti
Pubblicato in: Liver International, Numero 44, 2024, Pagina/e 1526-1536, ISSN 1478-3223
Editore: Blackwell Publishing Inc.
DOI: 10.1111/liv.15930

Reply to: “Polygenic risk score: A promising predictor for hepatocellular carcinoma in the population with non-alcoholic fatty liver disease”

Autori: Oveis Jamialahmadi, Cristiana Bianco, Serena Pelusi, Stefano Romeo, Luca Valenti
Pubblicato in: Journal of Hepatology, Numero 74, 2022, Pagina/e 1494-1496, ISSN 0168-8278
Editore: Elsevier BV
DOI: 10.1016/j.jhep.2021.02.030

Bio-inspired 3D-printed phantom: Encoding cellular heterogeneity for characterization of quantitative phase imaging

Autori: Sylvia Desissaire, Michał Ziemczonok, Tigrane Cantat-Moltrecht, Arkadiusz Kuś, Guillaume Godefroy, Lionel Hervé, Chiara Paviolo, Wojciech Krauze, Cédric Allier, Ondrej Mandula, Małgorzata Kujawińska
Pubblicato in: Measurement, Numero 247, 2025, Pagina/e 116765, ISSN 0263-2241
Editore: Elsevier BV
DOI: 10.1016/j.measurement.2025.116765

To Be or Not to Be

Autori: Luca V.C. Valenti, Alessandro Cherubini
Pubblicato in: Hepatology, Numero 74, 2024, Pagina/e 2942-2944, ISSN 0270-9139
Editore: John Wiley & Sons Inc.
DOI: 10.1002/hep.32096

Volumetric segmentation of biological cells and subcellular structures for optical diffraction tomography images

Autori: Martyna Mazur, Wojciech Krauze
Pubblicato in: Biomedical Optics Express, 2023, ISSN 0000-0000
Editore: Optica Publishing Group
DOI: 10.1364/boe.498275

Predictors of controlled attenuation parameter in metabolic dysfunction

Autori: Cristiana Bianco, Serena Pelusi, Sara Margarita, Federica Tavaglione, Oveis Jamialahmadi, Francesco Malvestiti, Giulia Periti, Jessica Rondena, Melissa Tomasi, Rossana Carpani, Luisa Ronzoni, Matteo Vidali, Ferruccio Ceriotti, Mirella Fraquelli, Umberto Vespasiani‐Gentilucci, Stefano Romeo, Daniele Prati, Luca Valenti
Pubblicato in: United European Gastroenterology Journal, Numero 12, 2024, Pagina/e 364-373, ISSN 2050-6406
Editore: Wiley Periodicals LLC
DOI: 10.1002/ueg2.12513

A remodeler switch from PBAF to BRM/cBAF regulates BMAL1 activity in the absence of circadian negative feedback

Autori: Letkova Dominika , Peticca Aurelie , Sery Damien , Seki Masahide , Suzuki Yutaka , Padmanabhan Kiran
Pubblicato in: Nature Communications, 2025, ISSN 0000-0000
Editore: -

SIRT5 rs12216101 T>G variant is associated with liver damage and mitochondrial dysfunction in patients with non-alcoholic fatty liver disease

Autori: Federico Salomone, Rosaria Maria Pipitone, Miriam Longo, Francesco Malvestiti, Angela Maria Amorini, Alfio Distefano, Elia Casirati, Ester Ciociola, Nunzio Iraci, Loredana Leggio, Rossella Zito, Nunzio Vicario, Concetta Saoca, Grazia Pennisi, Daniela Cabibi, Giuseppe Lazzarino, Anna Ludovica Fracanzani, Paola Dongiovanni, Luca Valenti, Salvatore Petta, Giovanni Li Volti, Stefania Grimaudo
Pubblicato in: Journal of Hepatology, Numero 80, 2024, Pagina/e 10-19, ISSN 0168-8278
Editore: Elsevier BV
DOI: 10.1016/j.jhep.2023.09.020

Hepatic estrogen receptor alpha drives masculinization in post-menopausal women with metabolic dysfunction-associated steatotic liver disease

Autori: Clara Meda, Valeria Benedusi, Alessandro Cherubini, Luca Valenti, Adriana Maggi, Sara Della Torre
Pubblicato in: JHEP Reports, Numero 6, 2024, Pagina/e 101143, ISSN 2589-5559
Editore: Elsevier
DOI: 10.1016/j.jhepr.2024.101143

Genetic risk scores and personalization of care in fatty liver disease

Autori: Cristiana Bianco, Federica Tavaglione, Stefano Romeo, Luca Valenti
Pubblicato in: Current Opinion in Pharmacology, Numero 61, 2023, Pagina/e 6-11, ISSN 1471-4892
Editore: Elsevier BV
DOI: 10.1016/j.coph.2021.08.014

Reply to: “Lack of hepatic autophagy promotes severity of liver injury but not steatosis”

Autori: Guido Baselli, Stefano Romeo, Luca Valenti
Pubblicato in: Journal of Hepatology, Numero 77, 2022, Pagina/e 1459-1461, ISSN 0168-8278
Editore: Elsevier BV
DOI: 10.1016/j.jhep.2022.07.026

Cell culture analysis through learning-enabled lens-free microscopy

Autori: Florian Lemarchand, Chiara Paviolo, Lionel Hervé, Lamya Ghenim, Kiran Padmanabhan, Cédric Allier
Pubblicato in: HAL Open Science, 2023, ISSN 0000-0000
Editore: HAL Open Science

Clinical and genetic determinants of the fatty liver–coagulation balance interplay in individuals with metabolic dysfunction

Autori: Luca Valenti, Armando Tripodi, Vincenzo La Mura, Serena Pelusi, Cristiana Bianco, Erica Scalambrino, Sara Margarita, Francesco Malvestiti, Luisa Ronzoni, Marigrazia Clerici, Roberta D’Ambrosio, Mirella Fraquelli, Rossana Carpani, Daniele Prati, Flora Peyvandi
Pubblicato in: JHEP Reports, Numero 4, 2024, Pagina/e 100598, ISSN 2589-5559
Editore: JHEP Reports
DOI: 10.1016/j.jhepr.2022.100598

Is there an ‘ideal’ diet for patients with NAFLD?

Autori: Nicola Pugliese, Maria Corina Plaz Torres, Salvatore Petta, Luca Valenti, Edoardo G. Giannini, Alessio Aghemo
Pubblicato in: European Journal of Clinical Investigation, Numero 52, 2023, ISSN 0014-2972
Editore: Blackwell Publishing Inc.
DOI: 10.1111/eci.13659

Circulating Interlukin-32 and Altered Blood Pressure Control in Individuals with Metabolic Dysfunction

Autori: Luca Valenti, Alessandro Cherubini
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 0000-0000
Editore: MDPI
DOI: 10.3390/ijms24087465

Metabolic dysfunction outperforms ultrasonographic steatosis to stratify <scp>hepatocellular carcinoma</scp> risk in patients with advanced hepatitis C cured with <scp>direct‐acting antivirals</scp>

Autori: Serena Pelusi, Cristiana Bianco, Massimo Colombo, Giuliana Cologni, Paolo del Poggio, Nicola Pugliese, Daniele Prati, Marie Graciella Pigozzi, Roberta D'Ambrosio, Pietro Lampertico, Stefano Fagiuoli, Luca Valenti, null null
Pubblicato in: Liver International, Numero 43, 2023, Pagina/e 1593-1603, ISSN 1478-3223
Editore: Blackwell Publishing Inc.
DOI: 10.1111/liv.15577

Impact of clonal hematopoiesis of indeterminate potential on hepatocellular carcinoma in individuals with steatotic liver disease

Autori: Alfredo Marchetti, Serena Pelusi, Alessio Marella, Francesco Malvestiti, Antony Ricchiuti, Luisa Ronzoni, Marta Lionetti, Vittoria Moretti, Elisabetta Bugianesi, Luca Miele, Umberto Vespasiani-Gentilucci, Paola Dongiovanni, Alessandro Federico, Giorgio Soardo, Roberta D’Ambrosio, Misti V. McCain, Helen L. Reeves, Vincenzo La Mura, Daniele Prati, Niccolò Bolli, Luca Valenti, null null
Pubblicato in: Hepatology, Numero 80, 2025, Pagina/e 816-827, ISSN 0270-9139
Editore: John Wiley & Sons Inc.
DOI: 10.1097/hep.0000000000000839

The contribution of genetics and epigenetics to MAFLD susceptibility

Autori: Vittoria Moretti, Stefano Romeo, Luca Valenti
Pubblicato in: Hepatology International, Numero 18, 2024, Pagina/e 848-860, ISSN 1936-0533
Editore: Springer Pub. Co.
DOI: 10.1007/s12072-024-10667-5

PNPLA3 as a therapeutic target for fatty liver disease: the evidence to date

Autori: Alessandro Cherubini, Elia Casirati, Melissa Tomasi, Luca Valenti
Pubblicato in: Expert Opinion on Therapeutic Targets, Numero 25, 2022, Pagina/e 1033-1043, ISSN 1472-8222
Editore: Ashley Publications Ltd.
DOI: 10.1080/14728222.2021.2018418

Adverse effect of <i>PNPLA3</i> p.I148M genetic variant on kidney function in middle‐aged individuals with metabolic dysfunction

Autori: Alessandro Mantovani, Serena Pelusi, Sara Margarita, Francesco Malvestiti, Michela Dell'Alma, Cristiana Bianco, Luisa Ronzoni, Daniele Prati, Giovanni Targher, Luca Valenti
Pubblicato in: Alimentary Pharmacology & Therapeutics, Numero 57, 2023, Pagina/e 1093-1102, ISSN 0269-2813
Editore: Blackwell Publishing Inc.
DOI: 10.1111/apt.17477

3D time-lapse imaging of a mouse embryo using intensity diffraction tomography embedded inside a deep learning framework

Autori: William Pierré, Lionel Hervé, Chiara Paviolo, Ondrej Mandula, Vincent Remondiere, Sophie Morales, Sergei Grudinin, Pierre F. Ray, Magali Dhellemmes, Christophe Arnoult, and Cédric Allier
Pubblicato in: Applied Optics, 2022, ISSN 0000-0000
Editore: Optica Publishing Group
DOI: 10.1364/ao.453910

Dysmetabolism, Diabetes and Clinical Outcomes in Patients Cured of Chronic Hepatitis C: A Real‐Life Cohort Study

Autori: Luca Valenti, Serena Pelusi, Alessio Aghemo, Sara Gritti, Luisa Pasulo, Cristiana Bianco, Claudia Iegri, Giuliana Cologni, Elisabetta Degasperi, Roberta D’Ambrosio, Paolo del Poggio, Alessandro Soria, Massimo Puoti, Isabella Carderi, Marie Graciella Pigozzi, Canio Carriero, Angiola Spinetti, Valentina Zuccaro, Massimo Memoli, Alessia Giorgini, Mauro Viganò, Maria Grazia Rumi, Tiziana Re, Ombret
Pubblicato in: Hepatology Communications, Numero 6, 2024, Pagina/e 867-877, ISSN 2471-254X
Editore: Hepatology Communications
DOI: 10.1002/hep4.1851

Segment and support: a dual-purpose deep learning solution for limited angle holographic tomography

Autori: Michał Gontarz, Wojciech Krauze, Vibekananda Dutta, Małgorzata Kujawińska
Pubblicato in: Optics Express, Numero 32, 2024, Pagina/e 46798, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.541288

Circulating indian hedgehog is a marker of the hepatocyte-TAZ pathway in experimental NASH and is elevated in humans with NASH

Autori: Mary Patricia Moore, Xiaobo Wang, Hongxue Shi, Marica Meroni, Alessandro Cherubini, Luisa Ronzoni, Elizabeth J. Parks, Jamal A. Ibdah, R. Scott Rector, Luca Valenti, Paola Dongiovanni, Ira Tabas
Pubblicato in: JHEP Reports, Numero 5, 2024, Pagina/e 100716, ISSN 2589-5559
Editore: Elsevier
DOI: 10.1016/j.jhepr.2023.100716

Roadmap on Digital Holography-Based Quantitative Phase Imaging

Autori: Vinoth Balasubramani, Małgorzata Kujawinska, Cédric Allier, Vijayakumar Anand, Chau-Jern Cheng, Christian Depeursinge, Nathaniel Hai, Saulius Juodkazis, Jeroen Kalkman, Arkadiusz Ku´s, Moosung Lee, Pierre J. Magistretti, Pierre Marquet, Soon Hock Ng, Joseph Rosen, Yong Keun Park, Michał Ziemczonok
Pubblicato in: Journal of imaging, 2021, ISSN 2313-433X
Editore: MDPI
DOI: 10.3390/jimaging7120252

Estrogen–ER‐α axis induces PNPLA3 p.I148M protein variant to promote steatotic liver disease susceptibility in women

Autori: Alessandro Cherubini, Elia Casirati, Serena Pelusi, Luca Valenti.
Pubblicato in: Clin Transl Med, 2024, ISSN 0000-0000
Editore: National Library of Medecine
DOI: 10.1002/ctm2.1524

Insights into Nonalcoholic Fatty-Liver Disease Heterogeneity

Autori: Marco Arrese, Juan P. Arab, Francisco Barrera, Benedikt Kaufmann, Luca Valenti, Ariel E. Feldstein
Pubblicato in: Seminars in Liver Disease, Numero 41, 2023, Pagina/e 421-434, ISSN 0272-8087
Editore: Thieme Medical Publishers
DOI: 10.1055/s-0041-1730927

CNN-based approach for 3D artifact correction of intensity diffraction tomography images

Autori: William Pierré, Matéo Briard, Guillaume Godefroy, Sylvia Desissaire, Magali Dhellemmes, Edgar Del Llano, Corinne Loeuillet, Pierre F. Ray, Christophe Arnoult, Cédric Allier, Lionel Hervé, Chiara Paviolo
Pubblicato in: Optics Express, Numero 32, 2024, Pagina/e 34825, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.523289

A PDCD1 Role in the Genetic Predisposition to NAFLD-HCC?

Autori: Nardeen Eldafashi, Rebecca Darlay, Ruchi Shukla, Misti Vanette McCain, Robyn Watson, Yang Lin Liu, Nikki McStraw, Moustafa Fathy, Michael Atef Fawzy, Marco Y. W. Zaki, Ann K. Daly, João P. Maurício, Alastair D. Burt, Beate Haugk, Heather J. Cordell, Cristiana Bianco, Jean-François Dufour, Luca Valenti, Quentin M. Anstee, Helen L. Reeves
Pubblicato in: Cancers, Numero 13, 2025, Pagina/e 1412, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13061412

Detecting abnormal cell behaviors from dry mass time series

Autori: Romain Bailly, Marielle Malfante, Cédric Allier, Chiara Paviolo, Lamya Ghenim, Kiran Padmanabhan, Sabine Bardin, Jérôme Mars
Pubblicato in: Scientific Reports, Numero 14, 2024, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-024-57684-w

Prevalence and Determinants of Liver Disease in Relatives of Italian Patients With Advanced MASLD

Autori: Serena Pelusi, Luisa Ronzoni, Jessica Rondena, Chiara Rosso, Grazia Pennisi, Paola Dongiovanni, Sara Margarita, Rossana Carpani, Giorgio Soardo, Daniele Prati, Annalisa Cespiati, Salvatore Petta, Elisabetta Bugianesi, Luca Valenti.
Pubblicato in: Clinical Gastroenterology and Hepatology, 2023, ISSN 0000-0000
Editore: Science Direct
DOI: 10.1016/j.cgh.2023.12.033

Genetic predisposition similarities between NASH and ASH: Identification of new therapeutic targets

Autori: Cristiana Bianco, Elia Casirati, Francesco Malvestiti, Luca Valenti
Pubblicato in: JHEP Reports, Numero 3, 2023, Pagina/e 100284, ISSN 2589-5559
Editore: JHEP Reports
DOI: 10.1016/j.jhepr.2021.100284

Definition of Healthy Ranges for Alanine Aminotransferase Levels: A 2021 Update

Autori: Luca Valenti, Serena Pelusi, Cristiana Bianco, Ferruccio Ceriotti, Alessandra Berzuini, Laura Iogna Prat, Roberta Trotti, Francesco Malvestiti, Roberta D’Ambrosio, Pietro Lampertico, Agostino Colli, Massimo Colombo, Emmanuel A. Tsochatzis, Mirella Fraquelli, Daniele Prati
Pubblicato in: Hepatology Communications, Numero 5, 2024, Pagina/e 1824-1832, ISSN 2471-254X
Editore: Hepatology Communications
DOI: 10.1002/hep4.1794

Reduced circulating FABP2 in patients with moderate to severe COVID-19 may indicate enterocyte functional change rather than cell death

Autori: G. Assante, A. Tourna, R. Carpani, F. Ferrari, D. Prati, F. Peyvandi, F. Blasi, A. Bandera, A. Le Guennec, S. Chokshi, V. C. Patel, I. J. Cox, L. Valenti, N. A. Youngson
Pubblicato in: Scientific Reports, Numero 12, 2022, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-23282-x

Numerical refractive index correction for the stitching procedure in tomographic quantitative phase imaging

Autori: Piotr Stępień, Michał Ziemczonok, Małgorzata Kujawińska, Maria Baczewska, Luca Valenti, Alessandro Cherubini, Elia Casirati, and Wojciech Krauze
Pubblicato in: Biomedical Optics Express, 2022, ISSN 0000-0000
Editore: Optica Publishing Group
DOI: 10.1364/boe.466403

Elevated plasma hepcidin concentrations are associated with an increased risk of mortality and nonfatal cardiovascular events in patients with type 2 diabetes: a prospective study

Autori: Alessandro Mantovani, Fabiana Busti, Nicolò Borella, Enrico Scoccia, Barbara Pecoraro, Elena Sani, Riccardo Morandin, Alessandro Csermely, Daniele Piasentin, Elisabetta Grespan, Annalisa Castagna, Josh Bilson, Christopher D. Byrne, Luca Valenti, Domenico Girelli, Giovanni Targher
Pubblicato in: Cardiovascular Diabetology, Numero 23, 2024, ISSN 1475-2840
Editore: BioMed Central
DOI: 10.1186/s12933-024-02377-x

Detailed stratified GWAS analysis for severe COVID-19 in four European populations

Autori: Luca Valenti, Alessandro Cherubini, Rossana Carpani
Pubblicato in: Human Molecular Genetics, 2022, ISSN 0964-6906
Editore: Oxford University Press
DOI: 10.1093/hmg/ddac158

Phase unwrapping using deep learning in holographic tomography

Autori: Michał Gontarz, Vibekananda Dutta, Małgorzata Kujawińska, Wojciech Krauze
Pubblicato in: Optics Express, 2023, ISSN 0000-0000
Editore: Optica Publishing Group
DOI: 10.1364/oe.486984

The genetics of portal hypertension: Recent developments and the road ahead

Autori: Sarah Shalaby, Luisa Ronzoni, Virginia Hernandez-Gea, Luca Valenti
Pubblicato in: Liver International, 2023, ISSN 0000-0000
Editore: Wiley Online Library
DOI: 10.1111/liv.15732

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality

Autori: Tomoko Nakanishi, Sara Pigazzini, Frauke Degenhardt, Mattia Cordioli, Guillaume Butler-Laporte, Douglas Maya-Miles, Luis Bujanda, Youssef Bouysran, Mari E.K. Niemi, Adriana Palom, David Ellinghaus, Atlas Khan, Manuel Martínez-Bueno, Selina Rolker, Sara Amitrano, Luisa Roade Tato, Francesca Fava, Christoph D. Spinner, Daniele Prati, David Bernardo, Federico Garcia, Gilles Darcis, Israel Fernández
Pubblicato in: Journal of Clinical Investigation, Numero 131, 2023, ISSN 1558-8238
Editore: Journal of Clinical Investigation
DOI: 10.1172/jci152386

Interaction between estrogen receptor-α and PNPLA3 p.I148M variant drives fatty liver disease susceptibility in women

Autori: Alessandro Cherubini, Mahnoosh Oveis Jamialahmadi, Serena Pelusi, Eniada Rrapaj, Elia Casirati, Giulia Passignani, Marjan Norouziesfahani, Elena Sinopoli, Guido Baselli, Clara Meda, Paola Dongiovanni, Daniele Dondossola, Neil Youngson, Aikaterini Tourna, Shilpa Chokshi, Elisabetta Bugianesi, Sara Della Torre, Daniele Prati, Stefano Romeo, Luca Valenti
Pubblicato in: Nature Medecine, 2023, ISSN 0000-0000
Editore: Nat Med
DOI: 10.1038/s41591-023-02553-8

The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis

Autori: Hamish Innes, Hans Dieter Nischalke, Indra Neil Guha, Karl Heinz Weiss, Will Irving, Daniel Gotthardt, Eleanor Barnes, Janett Fischer, M. Azim Ansari, Jonas Rosendahl, Shang‐Kuan Lin, Astrid Marot, Vincent Pedergnana, Markus Casper, Jennifer Benselin, Frank Lammert, John McLauchlan, Philip L. Lutz, Victoria Hamill, Sebastian Mueller, Joanne R. Morling, Georg Semmler, Florian Eyer, Johann von Fel
Pubblicato in: Hepatology Communications, Numero 6, 2024, Pagina/e 1213-1226, ISSN 2471-254X
Editore: Hepatology Communications
DOI: 10.1002/hep4.1886

Tailored 3D microphantoms: An essential tool for quantitative phase tomography analysis of organoids

Autori: Michał Ziemczonok, Sylvia Desissaire, Jérémy Neri, Arkadiusz Kuś, Lionel Hervé, Cécile Fiche, Guillaume Godefroy, Marie Fackeure, Damien Sery, Wojciech Krauze, Kiran Padmanabhan, Chiara Paviolo, Małgorzata Kujawińska
Pubblicato in: Biocybernetics and Biomedical Engineering, Numero 45, 2025, Pagina/e 247-257, ISSN 0208-5216
Editore: Polish Scientific Publishers PWN
DOI: 10.1016/j.bbe.2025.03.003

Multiscale and multipurpose phantoms for 2D/3D quantitative phase imaging

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