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CORDIS - Forschungsergebnisse der EU
CORDIS

Living Impact on Fetal Evolution: Shelter-Analyze-Validate-Empower Regulations

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Short brief: relevant policy status (öffnet in neuem Fenster)

D8.1 Short brief about the relevant policy status (M18) (IDEA, PROA). This deliverable relates to T8.1, compris-ing the first mapping of needs and options to impose, modify or develop new regulations based on existing in¬for¬ma¬tion.

Report on the held DICO workshops - Update 2 (öffnet in neuem Fenster)

D6.10 Report on the held DICO workshops - Update 2 (M36) (TPC). This deliverable relates to T6.4.

Report on the held DICO workshops - Update 1 (öffnet in neuem Fenster)

D6.9 Report on the held DICO workshops - Update 1 (M18) (TPC). This deliverable relates to T6.4.

Mechanical properties of bioprinted constructs (öffnet in neuem Fenster)

D2.3. Report on analysed and optimized mechanical properties of the bioprinted constructs for LIFESAVER elements (M30) (SEQ, i3S, INL, INRIM). This deliverable relates to T2.2 comprising the results of biomechani-cal assessment of the properties of the bioprinted constructs and data on normal uterine and decidua vis-costiffness, memory parameters with tissue orientation, location, anisotropy, frequency, applicable defor-mation strain (to the extent required for the objectives of the LIFESAVER).

Bioink characterisation results (öffnet in neuem Fenster)

D2.2. Bioinks physical, chemical and biological characterisation results (M18) (CELLINK, SEQ, NUI, INL, i3S, EVCYT). This deliverable relates to the second subtask of the Task T2.1 comprising results of characterized properties of the bioinks, relevant for bioprinting (flowability, construct rigidisation, viscosity, shear properties, nozzle compatibility, rate, printing precision, etc.) and for the cells com¬pa¬ti¬bi¬lity during and after the printing pro-cess.

Landscape analysis of current policy framework (öffnet in neuem Fenster)

D8.2 Analytical report with landscape analysis of current policy framework relevant to LIFESAVER and a gap analysis (M36) (IDEA, PROA). This deliverable relates to T8.1, T8.2 and T8.4, including overview of the cur¬rent state of the art of EU policies regarding chemicals and pharmaceuticals related to LIFESAVER.

Testing results with blank runs (öffnet in neuem Fenster)

D3.3. Testing results of microfluidic system with blank runs (M25) (ELV, i3S, NUI, INL, INRIM). This deliverable relates to T3.3 comprising results of the baseline (blank) tests for demonstration of the feasibility of the mi-crofluidic system operations.

Training activities & STEMs outcomes - Update 1 (öffnet in neuem Fenster)

D6.12 Report on training activities and STEMs outcomes - Update 1 (M18) (MLSC, TPC, ES). This deliverable re-lates to T6.4.

Optimized BDT parameters and SOPs (öffnet in neuem Fenster)

D1.3 Report on optimized parameters for the LIFESAVER device and SOPs recommendations (M36) (INRIM, ES, SEQ, i3S, INL, NUI). This deliverable relates to T1.3 comprising re¬com¬¬men¬dations for the in vitro/in silico twinning and obtained biofidelity, high¬lighting the limitations and appli¬ca¬tion limits of the LIFESAVER

Training activities & STEMs outcomes - Update 2 (öffnet in neuem Fenster)

D6.13 Report on training activities and STEMs outcomes - Update 2 (M36) (MLSC, TPC, ES). This deliverable re-lates to T6.4.

The first operational version of the LIFESAVER (öffnet in neuem Fenster)

D5.1 Demonstrated the first operational version of the LIFESAVER microfluidic system with proper controls and interfaces (M18) (ELV, INL, i3S). This deliverable relates to T5.1 including results of the demonstration of the feasibility of operation of the microfluidic hardware with the proper controls and ad sensors.

Feasible hACM tissues for RACE construction (öffnet in neuem Fenster)

D2.1. Demonstration of feasible hACM-based tissues prepared for RACE construction (M24) (EVCYT, UCSC, i3S, NUI, INRIM). This deliverable relates to the first subtask of the Task T2.1 comprising results and demon-stration of suitability of autologous/allogenic from another hACM source to be re-printed back in a controlled manner.

MCDA tool for analysis of biodigital twin data (öffnet in neuem Fenster)

D4.4 Demonstrated MCDA tool for analysis of the biodigital twin data (M36) (ES, INRIM, SEQ). This deliverable connects with T4.4, including demonstration of the application of the MCDA method integrating LIFESAVER outcomes and endpoints.

Improved feasible bioprinted REPE construct (öffnet in neuem Fenster)

D2.4. Demonstration of improved and feasible bioprinted REPE construct (M36) (CELLINK, INL, i3S, NUI, EVCYT). This deliverable is linked to T2.3 comprising the results and demonstration of the imporved biofabricated REPE element for in vitro testing.

Release of DMP - Data Management Plan (öffnet in neuem Fenster)

D6.2 Release of DMP (M6) (ES, ALL). This deliverable is related to Open Research Data Pilot (ORDP). This deliv-erable relates to T6.2.

Project website opened (öffnet in neuem Fenster)

D6.1 Project website opened (M3) (TPC, ES). This deliverable relates to T6.1.

Veröffentlichungen

LIFESAVER featured in Green Deal Support Office Newsletter

Autoren: Green Deal Support Office
Veröffentlicht in: 2024
Herausgeber: Green Deal Support Office

LIFESAVER feature in Green Deal Support Office Brochure

Autoren: Green Deal Support Office
Veröffentlicht in: 2023
Herausgeber: Green Deal Support Office

ConcePTION & LIFESAVER – Joining forces to improve maternal health & pregnancy pharmacovigilance

Autoren: IMI ConcePTION & LIFESAVER
Veröffentlicht in: 2024
Herausgeber: IMI-ConcPTION

ALTERNATIVE & LIFESAVER Workshop Regulatory Innovation and Health Safety

Autoren: ALTERNATIVE & LIFESAVER
Veröffentlicht in: 2024
Herausgeber: ALTERNATIVE

LIFESAVER Project Video on YouTube by Green Deal Support Office

Autoren: Green Deal Support Office
Veröffentlicht in: 2024
Herausgeber: Green Deal Support Office

LIFESAVER featured in Green Deal Support Office Video

Autoren: Green Deal Support Office
Veröffentlicht in: 2023
Herausgeber: Green Deal Support Office

AptaShield: A Universal Signal-Transduction System for Fast and High-Throughput Optical Molecular Biosensing (öffnet in neuem Fenster)

Autoren: Miguel António Dias Neves, Inês Mendes Pinto
Veröffentlicht in: ACS Sensors, Ausgabe 9, 2024, Seite(n) 1756-1762, ISSN 2379-3694
Herausgeber: American Chemical Society
DOI: 10.1021/acssensors.3c02762

Multi‐Parametric Decision System for Analytical Performance Assessment of Electrochemical (Bio)Sensors (öffnet in neuem Fenster)

Autoren: Daniel C. Moreira, Duarte Nuno Carvalho, Evelyn C. Santos, João B. Relvas, Miguel António Dias Neves, Inēs Mendes Pinto
Veröffentlicht in: Advanced Materials Technologies, Ausgabe 9, 2024, ISSN 2365-709X
Herausgeber: Wiley-VCH GmbH
DOI: 10.1002/admt.202301464

Standard Operating Procedure to Optimize Resazurin-Based Viability Assays (öffnet in neuem Fenster)

Autoren: Jessica Petiti, Laura Revel, Carla Divieto
Veröffentlicht in: Biosensors, Ausgabe 14, 2024, Seite(n) 156, ISSN 2079-6374
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios14040156

Unveiling the human fetal-maternal interface during the first trimester: biophysical knowledge and gaps (öffnet in neuem Fenster)

Autoren: Alice Masserdotti, Michael Gasik, Regina Grillari-Voglauer, Johannes Grillari, Anna Cargnoni, Paola Chiodelli, Andrea Papait, Marta Magatti, Jacopo Romoli, Sara Ficai, Lorena Di Pietro, Wanda Lattanzi, Antonietta Rosa Silini, Ornella Parolini
Veröffentlicht in: Frontiers in Cell and Developmental Biology, Ausgabe 12, 2024, ISSN 2296-634X
Herausgeber: Springer Nature
DOI: 10.3389/fcell.2024.1411582

Standardized Protocol for Resazurin-Based Viability Assays on A549 Cell Line for Improving Cytotoxicity Data Reliability (öffnet in neuem Fenster)

Autoren: Petiti Jessica, Caria Sabrina, Revel Laura, Pegoraro Mattia, and Divieto Carla
Veröffentlicht in: Cells, 2024, ISSN 2073-4409
Herausgeber: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/cells13231959

Rechte des geistigen Eigentums

MODEL-FREE TIME-INVARIANT EVALUATION OF TRANSPORT AND EFFICACY OF CHEMICALS AND DRUGS

Antrags-/Publikationsnummer: 20 2217875843
Datum: 2022-07-28
Antragsteller: SEQVERA LTD. OY

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