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CORDIS - Risultati della ricerca dell’UE
CORDIS

Living Impact on Fetal Evolution: Shelter-Analyze-Validate-Empower Regulations

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Short brief: relevant policy status (si apre in una nuova finestra)

D8.1 Short brief about the relevant policy status (M18) (IDEA, PROA). This deliverable relates to T8.1, compris-ing the first mapping of needs and options to impose, modify or develop new regulations based on existing in¬for¬ma¬tion.

Report on the held DICO workshops - Update 2 (si apre in una nuova finestra)

D6.10 Report on the held DICO workshops - Update 2 (M36) (TPC). This deliverable relates to T6.4.

Report on the held DICO workshops - Update 1 (si apre in una nuova finestra)

D6.9 Report on the held DICO workshops - Update 1 (M18) (TPC). This deliverable relates to T6.4.

Mechanical properties of bioprinted constructs (si apre in una nuova finestra)

D2.3. Report on analysed and optimized mechanical properties of the bioprinted constructs for LIFESAVER elements (M30) (SEQ, i3S, INL, INRIM). This deliverable relates to T2.2 comprising the results of biomechani-cal assessment of the properties of the bioprinted constructs and data on normal uterine and decidua vis-costiffness, memory parameters with tissue orientation, location, anisotropy, frequency, applicable defor-mation strain (to the extent required for the objectives of the LIFESAVER).

Bioink characterisation results (si apre in una nuova finestra)

D2.2. Bioinks physical, chemical and biological characterisation results (M18) (CELLINK, SEQ, NUI, INL, i3S, EVCYT). This deliverable relates to the second subtask of the Task T2.1 comprising results of characterized properties of the bioinks, relevant for bioprinting (flowability, construct rigidisation, viscosity, shear properties, nozzle compatibility, rate, printing precision, etc.) and for the cells com¬pa¬ti¬bi¬lity during and after the printing pro-cess.

Landscape analysis of current policy framework (si apre in una nuova finestra)

D8.2 Analytical report with landscape analysis of current policy framework relevant to LIFESAVER and a gap analysis (M36) (IDEA, PROA). This deliverable relates to T8.1, T8.2 and T8.4, including overview of the cur¬rent state of the art of EU policies regarding chemicals and pharmaceuticals related to LIFESAVER.

Testing results with blank runs (si apre in una nuova finestra)

D3.3. Testing results of microfluidic system with blank runs (M25) (ELV, i3S, NUI, INL, INRIM). This deliverable relates to T3.3 comprising results of the baseline (blank) tests for demonstration of the feasibility of the mi-crofluidic system operations.

Training activities & STEMs outcomes - Update 1 (si apre in una nuova finestra)

D6.12 Report on training activities and STEMs outcomes - Update 1 (M18) (MLSC, TPC, ES). This deliverable re-lates to T6.4.

Optimized BDT parameters and SOPs (si apre in una nuova finestra)

D1.3 Report on optimized parameters for the LIFESAVER device and SOPs recommendations (M36) (INRIM, ES, SEQ, i3S, INL, NUI). This deliverable relates to T1.3 comprising re¬com¬¬men¬dations for the in vitro/in silico twinning and obtained biofidelity, high¬lighting the limitations and appli¬ca¬tion limits of the LIFESAVER

Training activities & STEMs outcomes - Update 2 (si apre in una nuova finestra)

D6.13 Report on training activities and STEMs outcomes - Update 2 (M36) (MLSC, TPC, ES). This deliverable re-lates to T6.4.

The first operational version of the LIFESAVER (si apre in una nuova finestra)

D5.1 Demonstrated the first operational version of the LIFESAVER microfluidic system with proper controls and interfaces (M18) (ELV, INL, i3S). This deliverable relates to T5.1 including results of the demonstration of the feasibility of operation of the microfluidic hardware with the proper controls and ad sensors.

Feasible hACM tissues for RACE construction (si apre in una nuova finestra)

D2.1. Demonstration of feasible hACM-based tissues prepared for RACE construction (M24) (EVCYT, UCSC, i3S, NUI, INRIM). This deliverable relates to the first subtask of the Task T2.1 comprising results and demon-stration of suitability of autologous/allogenic from another hACM source to be re-printed back in a controlled manner.

MCDA tool for analysis of biodigital twin data (si apre in una nuova finestra)

D4.4 Demonstrated MCDA tool for analysis of the biodigital twin data (M36) (ES, INRIM, SEQ). This deliverable connects with T4.4, including demonstration of the application of the MCDA method integrating LIFESAVER outcomes and endpoints.

Improved feasible bioprinted REPE construct (si apre in una nuova finestra)

D2.4. Demonstration of improved and feasible bioprinted REPE construct (M36) (CELLINK, INL, i3S, NUI, EVCYT). This deliverable is linked to T2.3 comprising the results and demonstration of the imporved biofabricated REPE element for in vitro testing.

Release of DMP - Data Management Plan (si apre in una nuova finestra)

D6.2 Release of DMP (M6) (ES, ALL). This deliverable is related to Open Research Data Pilot (ORDP). This deliv-erable relates to T6.2.

Project website opened (si apre in una nuova finestra)

D6.1 Project website opened (M3) (TPC, ES). This deliverable relates to T6.1.

Pubblicazioni

LIFESAVER featured in Green Deal Support Office Newsletter

Autori: Green Deal Support Office
Pubblicato in: 2024
Editore: Green Deal Support Office

LIFESAVER feature in Green Deal Support Office Brochure

Autori: Green Deal Support Office
Pubblicato in: 2023
Editore: Green Deal Support Office

ConcePTION & LIFESAVER – Joining forces to improve maternal health & pregnancy pharmacovigilance

Autori: IMI ConcePTION & LIFESAVER
Pubblicato in: 2024
Editore: IMI-ConcPTION

ALTERNATIVE & LIFESAVER Workshop Regulatory Innovation and Health Safety

Autori: ALTERNATIVE & LIFESAVER
Pubblicato in: 2024
Editore: ALTERNATIVE

LIFESAVER Project Video on YouTube by Green Deal Support Office

Autori: Green Deal Support Office
Pubblicato in: 2024
Editore: Green Deal Support Office

LIFESAVER featured in Green Deal Support Office Video

Autori: Green Deal Support Office
Pubblicato in: 2023
Editore: Green Deal Support Office

AptaShield: A Universal Signal-Transduction System for Fast and High-Throughput Optical Molecular Biosensing (si apre in una nuova finestra)

Autori: Miguel António Dias Neves, Inês Mendes Pinto
Pubblicato in: ACS Sensors, Numero 9, 2024, Pagina/e 1756-1762, ISSN 2379-3694
Editore: American Chemical Society
DOI: 10.1021/acssensors.3c02762

Multi‐Parametric Decision System for Analytical Performance Assessment of Electrochemical (Bio)Sensors (si apre in una nuova finestra)

Autori: Daniel C. Moreira, Duarte Nuno Carvalho, Evelyn C. Santos, João B. Relvas, Miguel António Dias Neves, Inēs Mendes Pinto
Pubblicato in: Advanced Materials Technologies, Numero 9, 2024, ISSN 2365-709X
Editore: Wiley-VCH GmbH
DOI: 10.1002/admt.202301464

Standard Operating Procedure to Optimize Resazurin-Based Viability Assays (si apre in una nuova finestra)

Autori: Jessica Petiti, Laura Revel, Carla Divieto
Pubblicato in: Biosensors, Numero 14, 2024, Pagina/e 156, ISSN 2079-6374
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios14040156

Unveiling the human fetal-maternal interface during the first trimester: biophysical knowledge and gaps (si apre in una nuova finestra)

Autori: Alice Masserdotti, Michael Gasik, Regina Grillari-Voglauer, Johannes Grillari, Anna Cargnoni, Paola Chiodelli, Andrea Papait, Marta Magatti, Jacopo Romoli, Sara Ficai, Lorena Di Pietro, Wanda Lattanzi, Antonietta Rosa Silini, Ornella Parolini
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 12, 2024, ISSN 2296-634X
Editore: Springer Nature
DOI: 10.3389/fcell.2024.1411582

Standardized Protocol for Resazurin-Based Viability Assays on A549 Cell Line for Improving Cytotoxicity Data Reliability (si apre in una nuova finestra)

Autori: Petiti Jessica, Caria Sabrina, Revel Laura, Pegoraro Mattia, and Divieto Carla
Pubblicato in: Cells, 2024, ISSN 2073-4409
Editore: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/cells13231959

Diritti di proprietà intellettuale

MODEL-FREE TIME-INVARIANT EVALUATION OF TRANSPORT AND EFFICACY OF CHEMICALS AND DRUGS

Numero candidatura/pubblicazione: 20 2217875843
Data: 2022-07-28
Candidato/i: SEQVERA LTD. OY

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