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Learning from animals how to regenerate: multidisciplinary training programme in regenerative biology

Descrizione del progetto

Rete di formazione per la ricerca in biologia rigenerativa

Le capacità rigenerative dell’uomo sono limitate, a differenza di quelle di alcuni animali. Pertanto, individuando i principi comuni dei processi rigenerativi nei modelli animali, è possibile migliorare gli interventi rigenerativi nell’essere umano. Finanziato dal programma di azioni Marie Skłodowska-Curie, il progetto REGENERATE-IT unirà uno spettro di discipline per creare una rete di formazione per la ricerca per giovani scienziati nel campo della biologia rigenerativa. La rete comprenderà ricercatori che lavorano su diversi organismi modello rigenerativi, come vermi piatti, cnidari, crostacei, anfibi e pesci zebra, specialisti in materia di cellule staminali che lavorano su modelli murini e umani, partner industriali ed esperti nel campo delle tecnologie bioanalitiche. I tirocinanti del progetto comprenderanno i fondamenti della biologia rigenerativa e il potenziale della medicina rigenerativa.

Obiettivo

The REGENERATE-IT Network brings together a full spectrum of disciplines – from fundamental to applied research – to train the next generation of researchers in regenerative biology and adjacent fields. While the natural regenerative ability of humans is limited, some animals have remarkable regenerative capacity. For example, planarian flatworms can restore all body parts from small pieces of tissue, salamanders can grow back lost limbs and repair damaged eyes, and zebrafish can regenerate their heart and fins. By identifying the common biological principles underlying the regenerative processes in these different animal models, we can learn a great deal on how to improve regenerative interventions in humans. Currently, regenerative animal models are studied in isolation, preventing the discovery of such shared mechanisms, and the REGENERATE-IT Network fills this gap. ESRs trained by REGENERATE-IT will obtain a broad and unique understanding of the fundamentals of regenerative biology and of the needs of research in regenerative medicine. The REGENERATE-IT Network therefore includes scientists working on regenerative model organisms such as flatworms, cnidarians, crustaceans, amphibians and zebrafish; stem cell scientists working on mouse and human models; scientists with impressive track records in translational research and experience with clinical trials; and experts in key technologies such as genomics, single cell sequencing, imaging and drug screening. REGENERATE-IT will train 10 ESRs and 1 associated doctoral researcher through research, secondments to other laboratories, consortium meetings, and workshops covering a wide range of topics. In addition to consolidating European strengths in regenerative biology, and training a cohort of next-generation scientists capable of cross-disciplinary research, REGENERATE-IT will combine and deliver theoretical and technological breakthroughs, and advance the frontiers of regenerative biology and medicine.

Coordinatore

ACADEMISCH ZIEKENHUIS GRONINGEN
Contribution nette de l'UE
€ 274 370,40
Indirizzo
HANZEPLEIN 1
9713 GZ Groningen
Paesi Bassi

Mostra sulla mappa

Regione
Noord-Nederland Groningen Overig Groningen
Tipo di attività
Higher or Secondary Education Establishments
Collegamenti
Costo totale
Nessun dato

Partecipanti (9)

Partner (19)