EUropean network for neurodevelopmental RASopathies

Project Information

EURAS

Grant agreement ID: 101080580

DOI

10.3030/101080580

EC signature date 6 April 2023

Start date 1 June 2023

End date 31 May 2027

Funded under

• Health

Total cost

€ 8 048 715,25

EU contribution

€ 8 048 715,25

Coordinated by

UNIVERSITATSKLINIKUM ERLANGEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (1)

Patient Board is formed

Patient Board is formed and first session performed.

Websites, patent fillings, videos etc. (1)

Project website with contents for publics, experts, and patients

Regularly updated website with EURAS aims, activities and results, with public and secure area and links to social media channels

Data sets, microdata, etc (1)

Domain-specific set of common data elements (DCDEs) publication

The DCDEs for neurodevelopmental RASopathies defined and published.

Publications

Peer reviewed articles (6)

Celebrating the Birthday of AMPA Receptor Nanodomains: Illuminating the Nanoscale Organization of Excitatory Synapses with 10 Nanocandles

Author(s): Yuko Fukata, Masaki Fukata, Harold D. MacGillavry, Deepak Nair, Eric Hosy
Published in: The Journal of Neuroscience, Issue 44, 2024, ISSN 0270-6474
Publisher: Society for Neuroscience
DOI: 10.1523/JNEUROSCI.2104-23.2024

Exploring miRNA–target gene pair detection in disease with coRmiT

Author(s): Jose Cordoba-Caballero, James R Perkins, Federico García-Criado, Diana Gallego, Alicia Navarro-Sánchez, Mireia Moreno-Estellés, Concepción Garcés, Fernando Bonet, Carlos Romá-Mateo, Rocio Toro, Belén Perez, Pascual Sanz, Matthias Kohl, Elena Rojano, Pedro Seoane, Juan A G Ranea
Published in: Briefings in Bioinformatics, Issue 25, 2024, ISSN 1467-5463
Publisher: Oxford University Press (OUP)
DOI: 10.1093/bib/bbae060

Developmental effect of RASopathy mutations on neuronal network activity on a chip

Author(s): Eva-Maria Weiss, Debarpan Guhathakurta, Aneta Petrušková, Verena Hundrup, Martin Zenker, Anna Fejtová
Published in: Frontiers in Cellular Neuroscience, Issue 18, 2024, ISSN 1662-5102
Publisher: Frontiers Media SA
DOI: 10.3389/fncel.2024.1388409

Rasopathy-Associated Mutation Ptpn11D61Y has Age-Dependent Effect on Synaptic Vesicle Recycling

Author(s): Debarpan Guhathakurta, Franziska Selzam, Aneta Petrušková, Eva-Maria Weiss, Enes Yağız Akdaş, Carolina Montenegro-Venegas, Martin Zenker, Anna Fejtová
Published in: Cellular and Molecular Neurobiology, Issue 44, 2024, ISSN 0272-4340
Publisher: Springer Science and Business Media LLC
DOI: 10.1007/s10571-024-01505-1

Transcriptomic analysis identifies dysregulated pathways and therapeutic targets in PMM2-CDG

Author(s): Diana Gallego, Mercedes Serrano, Jose Cordoba-Caballero, Alejandra Gámez, Pedro Seoane, James R. Perkins, Juan A.G. Ranea, Belén Pérez
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Issue 1870, 2024, ISSN 0925-4439
Publisher: Elsevier BV
DOI: 10.1016/j.bbadis.2024.167163

Cytokine profiling and transcriptomics in mononuclear cells define immune variants in Meniere Disease

Author(s): Marisa Flook; Elena Rojano; Alvaro Gallego-Martinez; Alba Escalera-Balsera; Patricia Perez-Carpena; M. del Carmen Moleon; Rocio Gonzalez-Aguado; Victoria Rivero de Jesus; Emilio Domínguez-Durán; Lidia Frejo; Juan A. G. Ranea; Jose Antonio Lopez-Escamez
Published in: Genes and Immunity, Issue 25, 2024, ISSN 1476-5470
Publisher: Nature
DOI: 10.1038/s41435-024-00260-z