Continuous stratification for improved prevention, treatment, and rehabilitation of stroke patients using digital twins and AI

Informazioni relative al progetto

STRATIF-AI

ID dell’accordo di sovvenzione: 101080875

DOI

10.3030/101080875

Data della firma CE 21 Aprile 2023

Data di avvio 1 Maggio 2023

Data di completamento 30 Aprile 2027

Finanziato da

• Health

Costo totale

€ 5 698 475,00

Contributo UE

€ 5 698 475,00

Coordinato da

LINKOPINGS UNIVERSITET
Sweden

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (8)

Startup package for clinical study 3

Submission package, prior to enrolment of first subject in Clinical study 3. This contains the final version of the study protocol as submitted to regulators, a registration number of the CT in a WHO or ICMJE-approved registry and approvals from ethics committees and national competent authorities. This deliverable is available prior to enrolment of the first subject in clinical studies.

Startup package for clinical study 5

Submission package, prior to enrolment of first subject in Clinical study 5. This contains the final version of the study protocol as submitted to regulators, a registration number of the CT in a WHO or ICMJE-approved registry and approvals from ethics committees and national competent authorities. This deliverable is available prior to enrolment of the first subject in clinical studies.

Submitted ethical applications

Submitted ethical applications for all 6 clinical studies

Startup package for clinical study 4

Submission package, prior to enrolment of first subject in Clinical study 4. This contains the final version of the study protocol as submitted to regulators, a registration number of the CT in a WHO or ICMJE-approved registry and approvals from ethics committees and national competent authorities. This deliverable is available prior to enrolment of the first subject in clinical studies.

Dissemination and Communication Plan including Home Page

Communication and dissemination plan for the project, including development of the home page.

Startup package for clinical study 2

Submission package, prior to enrolment of first subject in Clinical study 2. This contains the final version of the study protocol as submitted to regulators, a registration number of the CT in a WHO or ICMJE-approved registry and approvals from ethics committees and national competent authorities. This deliverable is available prior to enrolment of the first subject in clinical studies.

Startup package for clinical study 6

Submission package, prior to enrolment of first subject in Clinical study 6. This contains the final version of the study protocol as submitted to regulators, a registration number of the CT in a WHO or ICMJE-approved registry and approvals from ethics committees and national competent authorities. This deliverable is available prior to enrolment of the first subject in clinical studies.

Startup package for clinical study 1

Submission package, prior to enrolment of first subject in Clinical study 1. This contains the final version of the study protocol as submitted to regulators, a registration number of the CT in a WHO or ICMJE-approved registry and approvals from ethics committees and national competent authorities. This deliverable is available prior to enrolment of the first subject in clinical studies.

Pubblicazioni

Peer reviewed articles (10)

Engineering Applications of Artificial Intelligence

Autori: Abad-Navarro, Francisco; Martínez Costa, Catalina; Fernández Breis, Jesualdo Tomás
Pubblicato in: Engineering Applications of Artificial Intelligence, 2025, ISSN 0952-1976
Editore: Pergamon Press Ltd.
DOI: 10.1016/J.ENGAPPAI.2025.112671

A physiologically-based digital twin for alcohol consumption – predicting real-life drinking responses and long-term plasma PEth

Autori: Henrik Podéus; Christian Simonsson; William Lövfors; Patrik Nasr; Mattias Ekstedt; Peter Lundberg; Gunnar Cedersund; Stergios Kechagias; Henrik Podéus; Christian Simonsson; Patrik Nasr; Mattias Ekstedt; Stergios Kechagias; Peter Lundberg; William Lövfors; Gunnar Cedersund
Pubblicato in: npj Digital Medicine, Numero 7, 2024, ISSN 2398-6352
Editore: Nature publishing group
DOI: 10.1038/S41746-024-01089-6

HURON: A Quantitative Framework for Assessing Human Readability in Ontologies

Autori: Francisco Abad-Navarro, Catalina Martínez-Costa, Jesualdo Tomás Fernández-Breis
Pubblicato in: IEEE Access, Numero 11, 2023, ISSN 2169-3536
Editore: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.1109/ACCESS.2023.3316512

Model-driven meta-analysis establishes a new consensus view: Inhibitory neurons dominate BOLD-fMRI responses

Autori: Nicolas Sundqvist; Henrik Podéus; Sebastian Sten; Maria Engström; Salvador Dura-Bernal; Gunnar Cedersund
Pubblicato in: Computers in Biology and Medicine, 2025, ISSN 1879-0534
Editore: Science direct
DOI: 10.1016/J.COMPBIOMED.2025.111014

How processing choices effect repeatability in BOLD–CVR imaging

Autori: Gustav Magnusson, Alex A Bhogal, Charalampos Georgiopoulos, Gunnar Cedersund, Lovisa Tobieson, Maria Engström, Anders Tisell
Pubblicato in: Journal of Cerebral Blood Flow & Metabolism, 2026, ISSN 0271-678X
Editore: SAGE Publications
DOI: 10.1177/0271678X261420026

A unified framework for prediction of liver steatosis dynamics in response to different diet and drug interventions

Autori: Christian Simonsson, Elin Nyman, Peter Gennemark, Peter Gustafsson, Ingrid Hotz, Mattias Ekstedt, Peter Lundberg, Gunnar Cedersund
Pubblicato in: Clinical Nutrition, Numero 43, 2024, ISSN 0261-5614
Editore: Elsevier BV
DOI: 10.1016/J.CLNU.2024.05.017

Predictors of social risk for post-ischemic stroke reintegration

Autori: Katryna K. Cisek, Thi Nguyet Que Nguyen, Alejandro Garcia-Rudolph, Joan Saurí, Helard Becerra Martinez, Andrew Hines, John D. Kelleher
Pubblicato in: Scientific Reports, Numero 14, 2024, ISSN 2045-2322
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41598-024-60507-7

Uncertainty in cardiovascular digital twins despite non-normal errors in 4D flow MRI: identifying reliable biomarkers such as ventricular relaxation rate

Autori: Kajsa Tunedal; Tino Ebbers; Gunnar Cedersund
Pubblicato in: Computers in Biology and Medicine, 2024, ISSN 1879-0534
Editore: Elsevier
DOI: 10.1016/J.COMPBIOMED.2025.109878

Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation

Autori: Niloofar Nikaein, Kedeye Tuerxun, Gunnar Cedersund, Daniel Eklund, Robert Kruse, Eva Särndahl, Eewa Nånberg, Antje Thonig, Dirk Repsilber, Alexander Persson, Elin Nyman
Pubblicato in: Journal of Biological Chemistry, Numero 299, 2023, ISSN 0021-9258
Editore: Journal of Biological Chemistry
DOI: 10.1016/j.jbc.2023.105205

Characterization, Outcomes, and Time to Event Predictors of Urinary Tract Infections Acquired During Postacute Stroke Inpatient Rehabilitation: A Comprehensive Cohort Study

Autori: Alejandro García-Rudolph; Sergiu Albu; Mark Andrew Wright; Maria del Mar Laya; Claudia Teixido; Eloy Opisso; Gunnar Cedersund; Montserrat Bernabeu
Pubblicato in: Archives of Physical Medicine and Rehabilitation, 2025, ISSN 1532-821X
Editore: ACRM
DOI: 10.1016/J.APMR.2024.10.007

Book chapters (4)

‘SNOMEDizing’ Questionnaires for Standardizing Stroke Registry Data

Autori: Andrea Riedel, Stefan Schulz, Catalina Martínez Costa
Pubblicato in: Digital Health and Informatics Innovations for Sustainable Health Care Systems, Numero 1453
Editore: IOS Press
DOI: 10.3233/SHTI240687

‘SNOMEDizing’ Questionnaires for Standardizing Stroke Registry Data

Autori: Riedel, Andrea; Schulz, Stefan; Martínez Costa, Catalina
Pubblicato in: Studies in Health Technology and Informatics - Digital Health and Informatics Innovations for Sustainable Health Care Systems, 2024
Editore: SAGE
DOI: 10.3233/SHTI240687

Semantic Representation of Medical Data Collection Forms Using Standards

Autori: Schulz, Stefan; Martínez Costa, Catalina
Pubblicato in: Studies in Health Technology and Informatics, Intelligent Health Systems – From Technology to Data and Knowledge, 2025
Editore: SAGE
DOI: 10.3233/SHTI250440

Estimating Population Burden of Stroke with an Agent-Based Model

Autori: Elizabeth Hunter; John D. Kelleher
Pubblicato in: Springer Proceedings in Complexity ISBN: 9783031577840, 2024
Editore: Springer
DOI: 10.48550/ARXIV.2405.19934