ERA Chair Holder to establish the electron cryo-microscopy analysis of cellular and artificial nanomachines

Project Information

hot4cryo

Grant agreement ID: 101086665

DOI

10.3030/101086665

EC signature date 14 October 2022

Start date 1 March 2023

End date 29 February 2028

Funded under

• Widening participation and spreading excellence

Total cost

€ 2 499 921,25

EU contribution

€ 2 499 921,00

Coordinated by

ETHNIKO IDRYMA EREVNON
Greece

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (1)

DEC Strategy and Plan

DEC Strategy and Plan: This deliverable will also be communicated at month 42.

Documents, reports (2)

Computational protocols for cryo-EM image analysis of ERA Chair specimen

Computational protocols for cryo-EM image analysis of ERA Chair specimen.

Data Management Plan (DMP)

Data Management Plan (DMP).

Publications

Peer reviewed articles (8)

Enabling cryo-EM density interpretation from yeast native cell extracts by proteomics data and AlphaFold structures

Author(s): Tüting C, Schmidt L, Skalidis I, Sinz A, Kastritis PL.
Published in: Proteomics, Issue Apr 4:e2200096, 2023, ISSN 1615-9861
Publisher: Wiley
DOI: 10.1002/pmic.202200096

Protein-Rich Rafts in Hybrid Polymer/Lipid Giant Unilamellar Vesicles

Author(s): Nika Otrin*, Lado Otrin, Claudia Bednarz, Toni K. Träger, Farzad Hamdi, Panagiotis L. Kastritis, Ivan Ivanov, and Kai Sundmacher
Published in: Biomacromolecules, Issue Feb 12;25(2):778-791, 2024, ISSN 1525-7797
Publisher: ACS Publications
DOI: 10.1021/acs.biomac.3c00972

Cryo-EM structure of a plant photosystem II supercomplex with light-harvesting protein Lhcb8 and α-tocopherol

Author(s): Opatíková M, Semchonok DA, Kopečný D, Ilík P, Pospíšil P, Ilíková I, Roudnický P, Zeljković SĆ, Tarkowski P, Kyrilis FL, Hamdi F, Kastritis PL, Kouřil R.
Published in: Nature Plants, Issue Aug;9(8):1359-1369, 2023, ISSN 2055-0278
Publisher: Nature Press
DOI: 10.1038/s41477-023-01483-0

Cryo-EM of a heterogeneous biochemical fraction elucidates multiple protein complexes from a multicellular thermophilic eukaryote

Author(s): Semchonok DA, Kyrilis FL, Hamdi F, Kastritis PL.
Published in: J Struct Biol: X, Issue Aug 9;8:100094, 2023, ISSN 2590-1524
Publisher: Elsevier
DOI: 10.1016/j.yjsbx.2023.100094

Delineating organizational principles of the endogenous L-A virus by cryo-EM and computational analysis of native cell extracts

Author(s): Lisa Schmidt, Christian Tüting, Fotis L. Kyrilis, Farzad Hamdi, Dmitry A. Semchonok, Gerd Hause, Annette Meister, Christian Ihling, Milton T. Stubbs, Andrea Sinz & Panagiotis L. Kastritis
Published in: Communications Biology, Issue May 10;7(1):557, 2024, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-024-06204-7

Structural biology in cellulo: Minding the gap between conceptualization and realization

Author(s): Fotis L Kyrilis, Jason K K Low, Joel P Mackay, Panagiotis L Kastritis
Published in: Current Opinion Structural Biology, Issue May 23:87:102843, 2024, ISSN 1879-033X
Publisher: Elsevier
DOI: 10.1016/j.sbi.2024.102843

Structural analysis of an endogenous 4-megadalton succinyl-CoA-generating metabolon

Author(s): Skalidis I, Kyrilis FL, Tüting C, Hamdi F, Träger TK, Belapure J, Hause G, Fratini M, O'Reilly FJ, Heilmann I, Rappsilber J, Kastritis PL.
Published in: Commun Biol, Issue May 22;6(1):552., 2023, ISSN 2399-3642
Publisher: Nature Press
DOI: 10.1038/s42003-023-04885-0

Cracking the code of cellular protein-protein interactions: Alphafold and whole-cell crosslinking to the rescue

Author(s): Träger T, Kastritis PL
Published in: Mol Syst Biol, Issue Apr 12;19(4):e11587, 2023, ISSN 1744-4292
Publisher: Nature Publishing Group
DOI: 10.15252/msb.202311587