Descrizione del progetto
Aumentare la capacità di sperimentazione clinica in Africa orientale
A causa dell’emergere di malattie infettive come HIV, ebola e COVID-19, la Comunità dell’Africa orientale (EAC) ha bisogno di competenze in materia di revisione scientifica ed etica, nonché di un solido quadro normativo per la ricerca. Il progetto SCALE-IT, finanziato dall’UE, mira a migliorare la capacità dell’EAC di esaminare la ricerca di alta qualità, di condurla e di supervisionarla secondo standard internazionali. Questo progetto fornirà una formazione su principi scientifici ed etici, nonché sulla conduzione di ricerche con progetti di studio emergenti e complessi. Offrirà inoltre una formazione sull’efficacia personale e sulle capacità di leadership per aiutare a gestire la crescente complessità dei processi di ricerca. L’Istituto per le malattie infettive dell’Uganda fungerà da ospite per SCALE-IT, mentre la Commissione per la ricerca sanitaria dell’Africa orientale coordinerà il progetto.
Obiettivo
The East African Community (EAC) has experienced significant increase in volume and complexity of clinical research driven by epidemics of emerging and remerging infectious diseases such as HIV, Ebola and COVID-19, requiring expertise in scientific and ethical review and conduct of research and a robust and pragmatic research regulatory framework. The overall goal is to strengthen scientific and ethics capacity in EAC for high quality research review, conduct and oversight, at international standards. The specific objectives are: 1. To train NRRA personnel, REC members, researchers and clinicians on scientific and ethics review and conduct of research with emerging and complex study designs including adaptive platform trials 2. To train NRRA personnel and REC members on oversight, monitoring and pharmacovigilance of clinical trials and 3. To train NRRA personnel, REC and research administrators on personal effectiveness and leadership skills (PELS) to manage the increasingly complex research processes. Methods: We will implement this project within a consortium of research scientists from the six partner states collaborating with the EU partner, with the East African Health Research Commission as the strong nucleus for coordination and dissemination of results. The project will be hosted at the Infectious Diseases Institute (IDI), where within a previous NIH funded program (5G11 TW011309-01) we built capacity for REC members, researchers and REC administrators for 7 RECs in Uganda, with significant improvement in knowledge, PELS, quality and turnaround time of research review and researcher satisfaction. This proposal fits within the scope of GH-EDCTP3-2022-01-05 call, whose aim is to strengthen clinical research capacity and improve efficiency of the regulatory environment for effective development, delivery and uptake of new and improved safe health technologies and rapid response to emerging epidemics guaranteeing international standards and attainment of SDG3.
Campo scientifico
Not validated
Not validated
Parole chiave
Programma(i)
- HORIZON.2.1 - Health Main Programme
Argomento(i)
Meccanismo di finanziamento
HORIZON-JU-CSA - HORIZON JU Coordination and Support ActionsCoordinatore
75019 Paris
Francia