Nanopore sequencing of cell-free DNA for the sensitive detection, molecular profiling and monitoring of childhood cancers

Projektinformationen

PaedsSeq

ID Finanzhilfevereinbarung: 101106070

DOI

10.3030/101106070

Projekt abgeschlossen

EK-Unterschriftsdatum 3 April 2023

Startdatum 1 Juni 2023

Enddatum 31 Mai 2025

Finanziert unter

• Marie Skłodowska-Curie Actions (MSCA)

Gesamtkosten

Keine Daten

EU-Beitrag

€ 220 908,48

Koordiniert durch

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (1)

Communication, Dissemination and Exploitation Plan

The plan describes the planned measures to maximize the impact of the project, including the dissemination and exploitation measures that are planned, and the target group(s) addressed. Regarding communication measures and public engagement strategy, the aim is to inform and reach out to society and show the activities performed, and the use and the benefits the project will have for citizens.

Data Management Plan (1)

Data Management Plan

The Data Management Plan describes the data management life cycle for all data sets that will be collected processed or generated by the action It is a document describing what data will be collected processed or generated and following what methodology and standards whether and how this data will be shared andor made open and how it will be curated and preserved

Veröffentlichungen

Peer reviewed articles (4)

SAVANA: reliable analysis of somatic structural variants and copy number aberrations using long-read sequencing

Autoren: Hillary Elrick, Carolin M. Sauer, Jose Espejo Valle-Inclan, Katherine Trevers, Melanie Tanguy, Sonia Zumalave, Solange De Noon, Francesc Muyas, Rita Cascão, Angela Afonso, Alistair G. Rust, Fernanda Amary, Roberto Tirabosco, Adam Giess, Timothy Freeman, Alona Sosinsky, Katherine Piculell, David T. Miller, Claudia C. Faria, Greg Elgar, Adrienne M. Flanagan, Isidro Cortes-Ciriano
Veröffentlicht in: Nature Methods, Ausgabe 22, 2025, ISSN 1548-7091
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1038/S41592-025-02708-0

Stratified Medicine Paediatrics: Cell free DNA and serial tumour sequencing identifies subtype specific cancer evolution and epigenetic states

Autoren: Sally L. George, Claire Lynn, Reda Stankunaite, Debbie Hughes, Carolin M. Sauer, Jane Chalker, Saira Waqar Ahmed, Minou Oostveen, Paula Z. Proszek, Lina Yuan, Ridwan Shaikh, Sabri Jamal, Ama Brew, Jennifer Tall, Tony Rogers, Steven C. Clifford, Josef Vormoor, Janet M. Shipley, Deborah A. Tweddle, Chris Jones, Courtney Willis, G.A. Amos Burke, Aditi Vedi, Lisa Howell, Robert Johnston, Helen Rees, Madeleine Adams, Angela Jesudason, Milind Ronghe, Martin Elliott, Emma Ross, Guy Makin, Quentin Campbell-Hewson, Richard G. Grundy, Jennifer Turnbull, Shaun Wilson, Victoria Lee, Juliet C. Gray, Sara Stoneham, Susanne A. Gatz, Lynley V. Marshall, Paola Angelini, John Anderson, George D. Cresswell, Trevor A. Graham, Bissan Al-Lazikani, Isidro Cortes-Ciriano, Pamela Kearns, J. Ciaran Hutchinson, Darren Hargrave, Thomas S. Jacques, Michael Hubank, Andrea Sottoriva, Louis Chesler
Veröffentlicht in: Cancer Discovery, 2024, ISSN 2159-8274
Herausgeber: American Association for Cancer Research (AACR)
DOI: 10.1158/2159-8290.CD-24-0916

SAVANA: reliable analysis of somatic structural variants and copy number aberrations in clinical samples using long-read sequencing

Autoren: Hillary Elrick; Carolin M Sauer; Jose Espejo Valle-Inclan; Katherine Trevers; Melanie Tanguy; Sonia Zumalave; Solange De Noon; Francesc Muyas; Rita Cascao; Angela Afonso; Fernanda Amary; Roberto Tirabosco; Adam Giess; Timothy Freeman; Alona Sosinsky; Katherine Piculell; David T Miller; Claudia C Faria; Greg Elgar; Adrienne M Flanagan; Isidro Cortes-Ciriano
Veröffentlicht in: Crossref, 2024, ISSN 2692-8205
Herausgeber: bioRxiv
DOI: 10.21203/RS.3.RS-4870639/V1

Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution

Autoren: Jose Espejo Valle-Inclan, Solange De Noon, Katherine Trevers, Hillary Elrick, Ianthe A.E.M. van Belzen, Sonia Zumalave, Carolin M. Sauer, Mélanie Tanguy, Thomas Butters, Francesc Muyas, Alistair G. Rust, Fernanda Amary, Roberto Tirabosco, Adam Giess, Alona Sosinsky, Greg Elgar, Adrienne M. Flanagan, Isidro Cortés-Ciriano
Veröffentlicht in: Cell, 2025, ISSN 0092-8674
Herausgeber: Elsevier BV
DOI: 10.1016/j.cell.2024.12.005