Collaborative development and dissemination of workflows and techniques for using Correlative Light, Electron and X-ray Microscopy to progress research into the understanding and treatment of diseases

Informazioni relative al progetto

CLEXM

ID dell’accordo di sovvenzione: 101120151

DOI

10.3030/101120151

Data della firma CE 9 Giugno 2023

Data di avvio 1 Settembre 2023

Data di completamento 31 Agosto 2027

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 2 480 594,40

Coordinato da

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Conference proceedings (4)

Integrating Cryo Soft X-Ray Tomography into CLEM and Volume EM Correlative Workflows

Autori: Sergey Kapishnikov, Paul Sheridan, William Fyans, Fergal O’Reilly, Tony McEnroe, Kenneth Fahy
Pubblicato in: Microscopy and Microanalysis, Numero 31, 2025, ISSN 1431-9276
Editore: Oxford University Press (OUP)
DOI: 10.1093/MAM/OZAF048.503

Spatially-Informed Multi-Stage Active Learning for Segmentation of Nucleus in Soft X-ray Tomography

Autori: Ayse Erozan, Alexander Zeilmann, Anthoula Chatzimpinou, Fariha Mahzabin Annesha, Vincent Heuveline, Venera Weinhardt
Pubblicato in: 2025 IEEE Symposium on Computational Intelligence in Image, Signal Processing and Synthetic Media (CISM), 2025
Editore: IEEE
DOI: 10.1109/CISM64958.2025.11060865

Elimination of HCV replication machinery early after antiviral treatment with DAA monitored by multimodal microscopy

Autori: Victoria Castro, Gema Calvo, Ana Pérez-Berna, David Rogers, Stephen O'Connor, Sergey Kapishnikov, Paul Sheridan, Eva Pereiro, Kenneth Fahy, Pablo Gastaminza
Pubblicato in: BIO Web of Conferences, Numero 129, 2024, ISSN 2117-4458
Editore: EDP Sciences
DOI: 10.1051/BIOCONF/202412918008

SARS-CoV-2 and HCV infection and antiviral treatment monitored by multimodal imaging

Autori: Ana Joaquina Perez-Berna, Kevin Mamprin, Victoria Castro, Gema Calvo, Ricardo Valcárcel, Eva Pereiro, Pablo Gastaminza
Pubblicato in: BIO Web of Conferences, Numero 129, 2024, ISSN 2117-4458
Editore: EDP Sciences
DOI: 10.1051/BIOCONF/202412916002

Peer reviewed articles (11)

Harnessing 3D cell models and high-resolution imaging to unveil the mechanisms of nanoparticle-mediated drug delivery

Autori: Alannah S. Chalkley, Maëva T. Lopez, Margaritha M. Mysior, Madeleen C. Brink, Suainibhe Kelly, Jeremy C. Simpson
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 13, 2025, ISSN 2296-4185
Editore: Frontiers Media SA
DOI: 10.3389/FBIOE.2025.1606573

The bacterial type three secretion system induces mechanoporation of vacuolar membranes

Autori: Léa Swistak, Marvin Albert, Camila Valenzuela, Elif Begum Gokerkucuk, François Bontems, Stéphane Tachon, Keith T. Egger, Anastasia D. Gazi, Anna Sartori-Rupp, Cammie F. Lesser, Perrine Paul-Gilloteaux, Jean-Yves Tinevez, Matthijn Vos, Jost Enninga
Pubblicato in: PLOS Biology, Numero 23, 2025, ISSN 1545-7885
Editore: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PBIO.3003135

<scp>CELS</scp>‐<scp>3D</scp>—Cutting edge light source for exciting fluorescence in microtome‐based <scp>3D</scp> microscopy and targeted correlative microscopy

Autori: Vladyslav Denyshchenko, Christopher Evans, Tiina O'Neill, Jakub Krstev, Emilia Filipczak, Silas O'Toole, Vladimir Lobaskin, Dimitri Scholz
Pubblicato in: Journal of Anatomy, Numero 246, 2024, ISSN 0021-8782
Editore: Wiley
DOI: 10.1111/JOA.14164

Histidine-modified UiO-66(Zr) nanoparticles as an effective pH-responsive carrier for 5-fluorouracil drug delivery system: A possible pathway to more effective brain cancer treatments

Autori: Alexandra Migasová, Ľuboš Zauška, Tomáš Zelenka, Dominik Volavka, Marta Férová, Terézia Gulyásová, Silvia Tomková, Michaela Saláková, Veronika Kuchárová, Tomáš Samuely, Jozef Bednarčík, Cyril Slabý, Mariana Máčajová, Boris Bilčík, Tim Schubert, Andreas Walter, Virginie Hornebecq, Veronika Huntošová, Miroslav Almáši
Pubblicato in: Chemical Engineering Journal, Numero 522, 2025, ISSN 1385-8947
Editore: Elsevier BV
DOI: 10.1016/J.CEJ.2025.167857

Rapid HCV Replication Machinery Removal after Antiviral Treatment with DAA Monitored by Multimodal Imaging

Autori: Victoria Castro, Gema Calvo, Ana Pérez-Berna, David Rogers, Stephen O’Connor, Sergey Kapishnikov, Paul Sheridan, Eva Pereiro, Kenneth Fahy, Pablo Gastaminza
Pubblicato in: Microscopy and Microanalysis, Numero 30, 2024, ISSN 1431-9276
Editore: Oxford University Press (OUP)
DOI: 10.1093/MAM/OZAE044.1056

Cryogenic Super-Resolution Fluorescence, Electron, and X-ray Microscopy -- A Novel Correlative Nanoscale Imaging Workflow to Reveal Nanoparticle Internalization into Cancer Cells

Autori: Pavitra Sokke Rudraiah, Louisa Herbsleb, Michaela Salakova, Henriette Gröger, Anna Maria Steyer, Frauke Alves, Claus Feldmann, Andreas Walter
Pubblicato in: 2025, ISSN 0362-4331
Editore: Wiley
DOI: 10.22541/AU.174798562.25512020/V1

Rapid hepatitis C virus replication machinery removal after antiviral treatment with DAA monitored by multimodal imaging

Autori: Victoria Castro, Gema Calvo, Ana J. Pérez-Berná, Kevin Mamprin, Sergey Kapishnikov, David Rogers, Stephen O'Connor, Paul Sheridan, Kenneth Fahy, Eva Pereiro, Pablo Gastaminza
Pubblicato in: Structure, Numero 33, 2025, ISSN 0969-2126
Editore: Elsevier BV
DOI: 10.1016/J.STR.2025.05.015

The VapBC Toxin–Antitoxin System Enhances<i>Shigella flexneri</i>Fitness Through Coordination of Metabolic Stress Adaptation and Virulence

Autori: Estelle Saifi, Elisabeth Ageron, Keith Egger, Caroline Reisacher, Eric Frapy, Morgan Lamberioux, Shelley Payne, Jost Enninga, Laurence Arbibe
Pubblicato in: 2025, ISSN 2692-8205
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.06.29.662172

Super-resolution mapping of the ankle link proteins ADGRV1 and PDZD7 in developing auditory hair cells

Autori: Baptiste Colcombet-Cazenave, Gaël Moneron, Antonio El Helou, David DiGregorio, Vincent Michel, Nicolas Wolff
Pubblicato in: iScience, Numero 28, 2025, ISSN 2589-0042
Editore: Elsevier BV
DOI: 10.1016/J.ISCI.2025.113190

Soft X-Ray Reveals Chromatin Remodeling in Human CD4 T Cells

Autori: Fariha Mahzabin Annesha, Ayse Erozan, Swetha Ananth, Oliver T Fackler, Venera Weinhardt
Pubblicato in: Microscopy and Microanalysis, Numero 31, 2025, ISSN 1431-9276
Editore: Oxford University Press (OUP)
DOI: 10.1093/MAM/OZAF048.393

Soft X-ray tomography reveals variations in B. subtilis biofilm structure upon tasA deletion

Autori: Chatzimpinou, Anthoula; Diehl, Anne; Harhoff, A Tobias; Driller, Kristina; Vanslembrouck, Bieke; Chen, Jian-Hua; Kairišs, Kristaps; Loconte, Valentina; Le Gros, Mark A; Larabell, Carolyn; Turgay, Kürşad; Oschkinat, Hartmut; Weinhardt, Venera
Pubblicato in: npj Biofilms and Microbiomes, 2025, ISSN 2055-5008
Editore: npj Biofilms Microbiomes
DOI: 10.1038/S41522-025-00659-0