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CORDIS - EU research results
CORDIS

Precision biomarker based on digital pathology and artificial intelligence to guide fast and cost-effective personalized treatment decision support for colorectal cancer patients

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Submitted publication of validation at an external hospital setting (opens in new window)

Scientific article or abstract that is submitted for publication. The publication will be led by Stavanger University Hospital.1) the institution will gather and structure the data and will lead submission of the publication; 2) both parties will be involved in planning the projects and analyzing and interpreting the data that forms the basis of the publication; 3) DoMore Diagnostics will analyze slides and generate patient classifications for the publication.

Submitted publication on validation on Dutch cohort and as predictive biomarker (opens in new window)

Scientific article led by UMC Utrecht with supportive evidence for guideline inclusion, commercialization, and clinical use.1) the institution will gather and structure the data and will lead submission of the publication; 2) both parties will be involved in planning the projects and analyzing and interpreting the data that forms the basis of the publication; 3) DoMore Diagnostics will analyze slides and generate patient classifications for the publication.

Publications

Clinical validation of Histotype Px Colorectal in patients in a U.S. colon cancer cohort. (opens in new window)

Author(s): Vidya Arole, Sepp De Raedt, Jessica Maupin, Sandra Boutros, Anne M. Noonan, Giovanni Lujan, Eric David Miller
Published in: Journal of Clinical Oncology, Issue 42, 2024, ISSN 0732-183X
Publisher: American Society of Clinical Oncology (ASCO)
DOI: 10.1200/JCO.2024.42.16_SUPPL.3622

Pathology Visions 2024 Overview (opens in new window)

Published in: Journal of Pathology Informatics, Issue 16, 2025, ISSN 2153-3539
Publisher: Elsevier BV
DOI: 10.1016/J.JPI.2025.100419

Complementary value of a digital pathology biomarker to post-surgery circulating tumor DNA in risk stratification of stage III colon cancer patients receiving adjuvant chemotherapy. (opens in new window)

Author(s): Ingrid Franken, Marie-Christine Bakker, Sjoerd G. Elias, Miangela M. Lacle, Nikolas Stathonikos, Carmen Rubio-Alarcon, Mark Sausen, Miriam Koopman, Gerrit A. Meijer, Geraldine R. Vink, Remond Fijneman, Sepp De Raedt, Karolina Cyll, Ole-Johan Skrede, Hanne Askautrud, Tarjei S. Hveem, Lao H. Saal, Torbjørn Furuseth, Andreas Kleppe, Jeanine Roodhart
Published in: Journal of Clinical Oncology, Issue 43, 2025, ISSN 0732-183X
Publisher: American Society of Clinical Oncology (ASCO)
DOI: 10.1200/JCO.2025.43.16_SUPPL.3604

554P Novel clinical decision support (CDS) system optimizing adjuvant chemotherapy (ACT) for colorectal cancer (CRC) by integrating deep learning and circulating tumor DNA (ctDNA) molecular residual disease (MRD): GALAXY histotyping (opens in new window)

Author(s): Y. Nakamura, W. Kildal, T. Misumi, M. Pradhan, J. Watanabe, O-J. Skrede, D. Kotani, S.D. Raedt, H. Bando, J. Kalsnes, H. Taniguchi, K. Liestøl, I. Takemasa, T.S. Hveem, T. Kato, M. Novelli, E. Oki, D.J. Kerr, T. Yoshino, A. Kleppe
Published in: Annals of Oncology, Issue 35, 2024, ISSN 0923-7534
Publisher: Elsevier BV
DOI: 10.1016/J.ANNONC.2024.08.623

Histotype Px Colorectal as an AI biomarker to guide use of adjuvant therapy in patients with resected colon cancer (opens in new window)

Author(s): Arole, V., De Raedt, S., Maupin, J. Boutros, S., Handley, D., Noonan, A.M., Miller, E., Lujan, G.
Published in: Journal of Pathology informatics, Issue 16, 2025
Publisher: Elsevier
DOI: 10.1016/J.JPI.2025.100419

Intellectual Property Rights

HISTOLOGICAL IMAGE ANALYSIS

Application/Publication number: 20 780593
Date: 2020-09-18
Applicant(s): DOMORE DIAGNOSTICS AS

HISTOLOGICAL IMAGE ANALYSIS

Application/Publication number: 18 800165
Date: 2018-11-09
Applicant(s): DOMORE DIAGNOSTICS AS

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