Precision biomarker based on digital pathology and artificial intelligence to guide fast and cost-effective personalized treatment decision support for colorectal cancer patients

Projektinformationen

Histotype Px

ID Finanzhilfevereinbarung: 101161792

DOI

10.3030/101161792

EK-Unterschriftsdatum 27 Juni 2024

Startdatum 1 Juni 2024

Enddatum 31 Mai 2026

Finanziert unter

• The European Innovation Council (EIC)

Gesamtkosten

€ 5 326 967,50

EU-Beitrag

€ 2 499 999,99

Koordiniert durch

DOMORE DIAGNOSTICS AS
Norway

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (2)

Submitted publication of validation at an external hospital setting

Scientific article or abstract that is submitted for publication. The publication will be led by Stavanger University Hospital.1) the institution will gather and structure the data and will lead submission of the publication; 2) both parties will be involved in planning the projects and analyzing and interpreting the data that forms the basis of the publication; 3) DoMore Diagnostics will analyze slides and generate patient classifications for the publication.

Submitted publication on validation on Dutch cohort and as predictive biomarker

Scientific article led by UMC Utrecht with supportive evidence for guideline inclusion, commercialization, and clinical use.1) the institution will gather and structure the data and will lead submission of the publication; 2) both parties will be involved in planning the projects and analyzing and interpreting the data that forms the basis of the publication; 3) DoMore Diagnostics will analyze slides and generate patient classifications for the publication.

Veröffentlichungen

Peer reviewed articles (3)

Clinical validation of Histotype Px Colorectal in patients in a U.S. colon cancer cohort.

Autoren: Vidya Arole, Sepp De Raedt, Jessica Maupin, Sandra Boutros, Anne M. Noonan, Giovanni Lujan, Eric David Miller
Veröffentlicht in: Journal of Clinical Oncology, Ausgabe 42, 2024, ISSN 0732-183X
Herausgeber: American Society of Clinical Oncology (ASCO)
DOI: 10.1200/JCO.2024.42.16_SUPPL.3622

Pathology Visions 2024 Overview

Veröffentlicht in: Journal of Pathology Informatics, Ausgabe 16, 2025, ISSN 2153-3539
Herausgeber: Elsevier BV
DOI: 10.1016/J.JPI.2025.100419

Complementary value of a digital pathology biomarker to post-surgery circulating tumor DNA in risk stratification of stage III colon cancer patients receiving adjuvant chemotherapy.

Autoren: Ingrid Franken, Marie-Christine Bakker, Sjoerd G. Elias, Miangela M. Lacle, Nikolas Stathonikos, Carmen Rubio-Alarcon, Mark Sausen, Miriam Koopman, Gerrit A. Meijer, Geraldine R. Vink, Remond Fijneman, Sepp De Raedt, Karolina Cyll, Ole-Johan Skrede, Hanne Askautrud, Tarjei S. Hveem, Lao H. Saal, Torbjørn Furuseth, Andreas Kleppe, Jeanine Roodhart
Veröffentlicht in: Journal of Clinical Oncology, Ausgabe 43, 2025, ISSN 0732-183X
Herausgeber: American Society of Clinical Oncology (ASCO)
DOI: 10.1200/JCO.2025.43.16_SUPPL.3604

Conference proceedings (2)

554P Novel clinical decision support (CDS) system optimizing adjuvant chemotherapy (ACT) for colorectal cancer (CRC) by integrating deep learning and circulating tumor DNA (ctDNA) molecular residual disease (MRD): GALAXY histotyping

Autoren: Y. Nakamura, W. Kildal, T. Misumi, M. Pradhan, J. Watanabe, O-J. Skrede, D. Kotani, S.D. Raedt, H. Bando, J. Kalsnes, H. Taniguchi, K. Liestøl, I. Takemasa, T.S. Hveem, T. Kato, M. Novelli, E. Oki, D.J. Kerr, T. Yoshino, A. Kleppe
Veröffentlicht in: Annals of Oncology, Ausgabe 35, 2024, ISSN 0923-7534
Herausgeber: Elsevier BV
DOI: 10.1016/J.ANNONC.2024.08.623

Histotype Px Colorectal as an AI biomarker to guide use of adjuvant therapy in patients with resected colon cancer

Autoren: Arole, V., De Raedt, S., Maupin, J. Boutros, S., Handley, D., Noonan, A.M., Miller, E., Lujan, G.
Veröffentlicht in: Journal of Pathology informatics, Ausgabe 16, 2025
Herausgeber: Elsevier
DOI: 10.1016/J.JPI.2025.100419

Rechte des geistigen Eigentums

Patent (2)

HISTOLOGICAL IMAGE ANALYSIS

Antrags-/Publikationsnummer: 20 780593
Datum: 2020-09-18
Antragsteller: DOMORE DIAGNOSTICS AS

HISTOLOGICAL IMAGE ANALYSIS

Antrags-/Publikationsnummer: 18 800165
Datum: 2018-11-09
Antragsteller: DOMORE DIAGNOSTICS AS