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Next generation methods to preserve farm animal biodiversity by optimizing present and future breeding options

Ziel

NEXTGEN proposes the bold step of using whole genome data to develop and optimise conservation genetic management of livestock diversity for the foreseeable future. The rationale for choosing whole genome data is to ‘future-proof’ DNA-based analysis in livestock conservation against upcoming changes in technology and analysis. Thus, in the context of whole genome data availability, our global objective is to develop cost-effective optimized methodologies for preserving farm-animal biodiversity, using cattle, sheep, and goats as model species. More specifically, NEXTGEN will: - produce whole genome data in selected populations; - develop the necessary bioinformatics approaches, taking advantage of the 1000 human genomes project, and focusing on the identification of genomic regions under recent selection (adaptive / neutral variation); - develop the methods for optimizing breeding and biobanking, taking into account both neutral and adaptive variations; - develop innovative biobanking methods based on freeze-dried nuclei; - provide guidelines for studying disease resistance and genome/environment relationships in a spatial context; - assess the value of wild ancestors and breeds from domestication centres as genetic resources; - assess the performance of a surrogate marker system compared with whole genome sequence data for preserving biodiversity; - provide efficient training and a wide dissemination of the improved methodologies. The consortium has been designed to specifically reach these objectives, and encompasses skills in conservation genetics, bioinformatics, biobanking and breeding technologies, GIScience. The work plan has been established with great care. The sequencing task has been postponed to year 3 to take advantage of cost dynamics, while the two first years are dedicated to bioinformatics and to an innovative sampling strategy that fully integrates the spatial aspect and that offers more value at the data analysis stage.

Aufforderung zur Vorschlagseinreichung

FP7-KBBE-2009-3
Andere Projekte für diesen Aufruf anzeigen

Koordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Adresse
Rue Michel Ange 3
75794 Paris
Frankreich
Aktivitätstyp
Other
EU-Beitrag
€ 1 257 443
Kontakt Verwaltung
Guillaume Rochet (Mr.)

Beteiligte (10)

CARDIFF UNIVERSITY
United Kingdom
EU-Beitrag
€ 253 968
Adresse
Newport Road 30-36
CF24 ODE Cardiff
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Nick Bodycombe (Mr.)
UNIVERSITA CATTOLICA DEL SACRO CUORE
Italien
EU-Beitrag
€ 250 376
Adresse
Largo Gemelli 1
20123 Milano
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Libero Ranelli (Dr.)
PARCO TECNOLOGICO PADANO S.R.L.
Italien
EU-Beitrag
€ 236 880
Adresse
Via Einstein - Localita Cascina Codazza
26900 Lodi
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Gianluca Carenzo (Dr.)
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Deutschland
EU-Beitrag
€ 353 104
Adresse
Meyerhofstrasse 1
69117 Heidelberg
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Tom Ratcliff (Mr.)
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Schweiz
EU-Beitrag
€ 189 504
Adresse
Batiment Ce 3316 Station 1
1015 Lausanne
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Véronique Boillat-Kireev (Ms.)
UNIVERSITA DEGLI STUDI DI TERAMO
Italien
EU-Beitrag
€ 135 828
Adresse
Via Renato Balzarini 1 3 5 7
64100 Teramo
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Maria Luigia Scuteri (Dr.)
MAKERERE UNIVERSITY
Uganda
EU-Beitrag
€ 109 200
Adresse
Main Campus
256 Kampala
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Vincent Muwanika (Dr.)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
Marokko
EU-Beitrag
€ 143 808
Adresse
Avenue De La Victoire
10000 Rabat
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Mohamed Badraoui (Prof.)
Gorgan University of Agricultural Science and Natural resources
Iran
EU-Beitrag
€ 69 888
Adresse
Shahid Beheshti Street
4913815749 Gorgan
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Hassan Soltanloo (Dr.)
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
Australien
Adresse
Clunies Ross Street Csiro Black Mountain Science And Innovation Park
2601 Acton Act
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
James Kijas (Dr.)