Obiettivo In this proposal we intend to develop a new medicinal chemistry concept base on cell-personalized delivery of tailored drugs. Relying on basic chemical tools such as proximity-induced acyl transfer reactions and catalytic turnover- we will use RNA biomarkers of cancer cells to trigger the specific expression of cytotoxic drugs. This approach, in addition to contribute to basic science in chemistry and chemical and cell biology and suggest new therapeutic strategies, might allow to overcome the most important observed complications in cancer treatment: selectivity and resistance. Campo scientifico medical and health sciencesbasic medicinemedicinal chemistrynatural sciencesbiological sciencesbiochemistrybiomoleculesnatural sciencesbiological sciencescell biologymedical and health sciencesclinical medicineoncologynatural sciencesbiological sciencesgeneticsRNA Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) FP7-PEOPLE-2010-IEF - Marie-Curie Action: "Intra-European fellowships for career development" Invito a presentare proposte FP7-PEOPLE-2010-IEF Vedi altri progetti per questo bando Meccanismo di finanziamento MC-IEF - Intra-European Fellowships (IEF) Coordinatore HUMBOLDT-UNIVERSITAET ZU BERLIN Contributo UE € 163 242,40 Indirizzo UNTER DEN LINDEN 6 10117 Berlin Germania Mostra sulla mappa Regione Berlin Berlin Berlin Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Ulrich Winderl (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
