Obiettivo Human papillomavirus (HPV) is responsible for approximately 25% of head and neck cancer (HNC) worldwide and appears to be associated with a better response to treatment and improved prognosis. Evidence suggests that HPV-induced HNC has steadily increased in the USA and some European countries in the last decades. However, whether this is a worldwide phenomenon and specific risk factors are associated with it remains to be proven. In addition, little is known on the natural history and risk factors of oral HPV infection. HPV-AHEAD network aims to address these and other unanswered questions on HNC etiology and epidemiology with a focus on the role of HPV. We will assemble and analyze a large collection of plasma/sera and HNC tissues from 42 centres in 16 European countries as well as HNC tissues from 7 Indian centres together with epidemiological and clinical data. HPV status in human specimens will be evaluated by different assays in central laboratories. Epidemiological studies will be conducted to establish the overall proportion and type distribution of HPV-positive HNC at different anatomical sites in European and Indian regions as well as the time trend of the proportion of HPV-positive HNC in recent decades. Using the follow-up information on HNC patients, we will further investigate whether HPV positivity confers a better prognosis and survival. We will also conduct a study in HPV-vaccinated and non-vaccinated women in order to determine risk factors and natural history of oral HPV infections. In addition, we will search for new surrogate markers for oral HPV infection to facilitate novel screening strategies. Finally, the HPV-AHEAD consortium aims to transfer technology to Indian centres as well as to develop several strategies for the training of European and Indian researchers in infections and cancers. This study will provide important insights for the screening, diagnosis, treatment and prophylaxis of HPV-associated HNC in Europe, India and elsewhere. Campo scientifico humanitieshistory and archaeologyhistorymedical and health scienceshealth sciencespublic healthepidemiologymedical and health sciencesclinical medicineoncologyhead and neck cancermedical and health sciencesclinical medicineoncologycervical cancermedical and health scienceshealth sciencesinfectious diseasesDNA viruses Programma(i) FP7-HEALTH - Specific Programme "Cooperation": Health Argomento(i) HEALTH.2011.2.4.1-3 - Epidemiology and aetiology of infection-related cancers Invito a presentare proposte FP7-HEALTH-2011-single-stage Vedi altri progetti per questo bando Meccanismo di finanziamento CP-FP - Small or medium-scale focused research project Coordinatore CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER Contributo UE € 1 217 848,80 Indirizzo 25 AVENUE TONY GARNIER 69007 Lyon 7eme Francia Mostra sulla mappa Regione Auvergne-Rhône-Alpes Rhône-Alpes Rhône Tipo di attività Research Organisations Contatto amministrativo Olaf Kelm (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (10) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG Germania Contributo UE € 424 272,00 Indirizzo IM NEUENHEIMER FELD 280 69120 Heidelberg Mostra sulla mappa Regione Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Tipo di attività Research Organisations Contatto amministrativo Bettina Crispin (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE Partecipazione conclusa Spagna Contributo UE Nessun dato Indirizzo AVENIDA GRAN VIA HOSPITALET 199-203 08908 L'Hospitalet De Llobregat Mostra sulla mappa Regione Este Cataluña Barcelona Tipo di attività Research Organisations Contatto amministrativo Victoria Cochrane (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITEIT ANTWERPEN Belgio Contributo UE € 200 004,00 Indirizzo PRINSSTRAAT 13 2000 Antwerpen Mostra sulla mappa Regione Vlaams Gewest Prov. Antwerpen Arr. Antwerpen Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Anne Adams (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato ISTITUTO EUROPEO DI ONCOLOGIA SRL Italia Contributo UE € 217 800,00 Indirizzo VIA FILODRAMMATICI 10 20121 Milano Mostra sulla mappa Regione Nord-Ovest Lombardia Milano Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Ilaria Foti (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato ARISTOTELIO PANEPISTIMIO THESSALONIKIS Grecia Contributo UE € 149 960,00 Indirizzo KEDEA BUILDING, TRITIS SEPTEMVRIOU, ARISTOTLE UNIVERSITY CAMPUS 546 36 THESSALONIKI Mostra sulla mappa Regione Βόρεια Ελλάδα Κεντρική Μακεδονία Θεσσαλονίκη Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Georgia Petridou (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato DEUTSCHES INSTITUT FUER ERNAEHRUNGSFORSCHUNG POTSDAM REHBRUECKE Germania Contributo UE € 199 285,00 Indirizzo Arthur-Scheunert-Allee 114-116 14558 Nuthetal Mostra sulla mappa Regione Brandenburg Brandenburg Potsdam-Mittelmark Tipo di attività Research Organisations Contatto amministrativo Judith Schaefer (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITATSKLINIKUM HEIDELBERG Germania Contributo UE € 181 800,00 Indirizzo IM NEUENHEIMER FELD 672 69120 Heidelberg Mostra sulla mappa Regione Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Thorsten Brietz (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY India Contributo UE € 110 000,00 Indirizzo MILLENIUM PARKWAY JAGATHY 695 014 THIRUVANANTHAPURAM Mostra sulla mappa Tipo di attività Research Organisations Contatto amministrativo Rajan Panicker (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato ROCHE MTM LABORATORIES AG Germania Contributo UE € 98 018,20 Indirizzo IM NEUENHEIMER FELD 583 69120 HEIDELBERG Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Karin Mueller (Mrs.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato INSTITUT CATALA D'ONCOLOGIA Spagna Contributo UE € 200 958,00 Indirizzo AV GRAN VIA DE L'HOSPITALET 199-203 08908 L'HOSPITALET DEL LLOBREGAT Mostra sulla mappa Regione Este Cataluña Barcelona Tipo di attività Research Organisations Contatto amministrativo Cristina Rajo Anadón (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato