Obiettivo The primary aim of this project is to develop novel bacteriophage based strategies to combat Proteus mirabilis catheter associated urinary tract infection (CAUTI), a prevalent health-care associated infection for which there are currently no effective countermeasures. Indwelling urethral catheters (IUC) are the most commonly deployed medical devices, it is estimated that ~100 million IUC are used annually in healthcare systems globally, which equates to ~190 catheterisations per minute. However, IUC are vulnerable to infection, undermining their utility, jeopardising patient welfare and posing a substantial economic burden on healthcare systems. Over 40% of CAUTIs may be attributed to P. mirabilis, which poses particular problems in the care of catheterised patients. P. mirabilis causes encrustation and blockage of catheters, leading to serious complications such as pyelonephritis, septicaemia and shock. It is difficult to eliminate from the catheterised urinary tract, even after the catheter is removed, and often causes chronic infection recalcitrant to conventional antibiotic therapy. Given the prolific use of IUC and corresponding prevalence of CAUTIs in healthcare systems across the world, development of bacteriophage based strategies for control of CAUTIs would open a niche in a global market that is projected to reach an annual value of €2 billion by 2015. Campo scientifico medical and health sciencesclinical medicineurology Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) FP7-PEOPLE-2011-IAPP - Marie Curie Action: "Industry-Academia Partnerships and Pathways" Invito a presentare proposte FP7-PEOPLE-2011-IAPP Vedi altri progetti per questo bando Meccanismo di finanziamento MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP) Coordinatore UNIVERSITY OF BRIGHTON Contributo UE € 371 007,00 Indirizzo LEWES ROAD MITHRAS HOUSE BN2 4AT Brighton Regno Unito Mostra sulla mappa Regione South East (England) Surrey, East and West Sussex Brighton and Hove Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Brian Jones (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (3) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto BIOCONTROL LIMITED Regno Unito Contributo UE € 195 525,00 Indirizzo GEORGE STREET 79 PO33 2JF ISLE OF WIGHT Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Mark Enright (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK Irlanda Contributo UE € 388 826,00 Indirizzo WESTERN ROAD T12 YN60 Cork Mostra sulla mappa Regione Ireland Southern South-East Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo David O'connell (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY Irlanda Contributo UE € 122 956,00 Indirizzo Oak Park R93 Carlow Mostra sulla mappa Regione Ireland Southern South-East Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Mary O'brien (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato