Skip to main content

Enhanced exposure assessment and omic profiling for high priority environmental exposures in Europe

Ziel

This project aims to predict individual disease risk related to the environment, by characterizing the external and internal exposome for common exposures (air and drinking water contaminants) during critical periods of life, including in utero. A large amount of health data is now available from longitudinal cohorts in both children and adults, with detailed information on risk factors, confounders and outcomes, but these are not well linked with environmental exposure data. The exposome concept refers to the totality of environmental exposures from conception onwards, and is a novel approach to studying the role of the environment in human disease. This project will move the field forward by utilising data on individual external exposome (including sensors, smartphones, geo-referencing, satellites), and omic profiles in an agnostic search for new and integrated biomarkers. These tools will be applied in both experimental short-term studies and long-term longitudinal studies in humans. The ultimate goal is to use the new tools in risk assessment and in the estimation of the burden of environmental disease. The involvement of two SMEs, one specialized in sensors and smartphone development, the other in complex data integration, will increase the chances of a successful impact on European Public Health. This multidisciplinary proposal combines:
• development of a general framework for the systematic measurement of the internal and external exposome in Europe in relation to air and water contamination, as a way to reduce uncertainty in risk assessment and to address the effects of mixtures and complex exposures;
• evaluation of health outcomes and key physiological changes in short-term studies (including a randomized trial) and life-course studies with a large amount of information on diet, physical activity and anthropometry;
• evaluation of the burden of disease in the European population, based on state-of-the-art assessment of population exposures.

Aufforderung zur Vorschlagseinreichung

FP7-ENV-2012-two-stage
Andere Projekte für diesen Aufruf anzeigen

Koordinator

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Adresse
South Kensington Campus Exhibition Road
SW7 2AZ London
United Kingdom
Aktivitätstyp
Higher or Secondary Education Establishments
EU-Beitrag
€ 1 246 767,40
Kontakt Verwaltung
Tatjana Palalic (Ms.)

Beteiligte (13)

FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL

Beteiligung beendet

Spanien
EU-Beitrag
€ 1 185 106
Adresse
Calle Doctor Aiguader 88
08003 Barcelona
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Manolis Kogevinas (Prof.)
UNIVERSITEIT UTRECHT
Niederlande
EU-Beitrag
€ 1 361 304
Adresse
Heidelberglaan 8
3584 CS Utrecht
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Roel Vermeulen (Dr.)
CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER
Frankreich
EU-Beitrag
€ 1 130 151,60
Adresse
150 Cours Albert Thomas
69372 Lyon Cedex 08
Aktivitätstyp
Other
Kontakt Verwaltung
Olaf Kelm (Dr.)
FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spanien
Adresse
C Rossello 132 Planta 05
08036 Barcelona
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Manolis Kogevinas (Prof.)
UNIVERSITEIT MAASTRICHT
Niederlande
EU-Beitrag
€ 1 444 272
Adresse
Minderbroedersberg 4
6200 MD Maastricht
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
René Reijnders (Mr.)
ETHNIKO IDRYMA EREVNON
Greece
EU-Beitrag
€ 222 360
Adresse
Vas Konstantinou 48
11635 Athina
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Ioanna Petrochilou (Mrs.)
SCHWEIZERISCHES TROPEN- UND PUBLIC HEALTH-INSTITUT
Schweiz
EU-Beitrag
€ 482 417
Adresse
Socinstrasse 57
CH-4002 Basel
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Nicole Probst-Hensch (Prof.)
KING'S COLLEGE LONDON
United Kingdom
EU-Beitrag
€ 632 318
Adresse
Strand
WC2R 2LS London
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Paul Labbett (Mr.)
GENEDATA AG
Schweiz
EU-Beitrag
€ 461 380
Adresse
Margarethenstrasse 38
4053 Basel
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Timo Wittenberger (Dr.)
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Vereinigte Staaten
EU-Beitrag
€ 245 450,80
Adresse
Franklin Street 1111, 12 Floor
94607 Oakland Ca
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Jyl Baldwin (Ms.)
UNIVERSITY OF BRISTOL
United Kingdom
EU-Beitrag
€ 77 830
Adresse
Beacon House Queens Road
BS8 1QU Bristol
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Elodie Mahieu-Wedande (Mrs.)
NTRAM GENERAL S.A.
Spanien
EU-Beitrag
€ 259 272
Adresse
Calle Victor Pradera 45
08940 Cornella De Llobregat Barcelona
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Alicja Grzegorzek (Ms.)
UNIVERSITEIT HASSELT
Belgien
Adresse
Martelarenlaan 42
3500 Hasselt
Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Ilse Haeldermans (Dr.)