Safeguarding Cell Identities: Mechanisms Counteracting Cell Fate Reprogramming

The CONJUDOR pipeline for multiplexed knockdown of gene pairs identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans

Autori: Marlon Kazmierczak, Carlota Farré i Díaz, Andreas Ofenbauer, Sergej Herzog, Baris Tursun
Pubblicato in: Nucleic Acids Research, Numero 49/4, 2020, Pagina/e e22-e22, ISSN 0305-1048
Editore: Oxford University Press
DOI: 10.1093/nar/gkaa1171

Increasing Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neurons

Autori: Stefanie Seelk, Irene Adrian-Kalchhauser, Balázs Hargitai, Martina Hajduskova, Silvia Gutnik, Baris Tursun, Rafal Ciosk
Pubblicato in: eLife, Numero 5, 2016, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/eLife.15477

FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells

Autori: Ena Kolundzic, Andreas Ofenbauer, Selman I. Bulut, Bora Uyar, Gülkiz Baytek, Anne Sommermeier, Stefanie Seelk, Mei He, Antje Hirsekorn, Dubravka Vucicevic, Altuna Akalin, Sebastian Diecke, Scott A. Lacadie, Baris Tursun
Pubblicato in: Developmental Cell, Numero 46/5, 2018, Pagina/e 611-626.e12, ISSN 1534-5807
Editore: Cell Press
DOI: 10.1016/j.devcel.2018.07.006

The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans

Autori: Stefanie Müthel, Bora Uyar, Mei He, Anne Krause, Burcu Vitrinel, Selman Bulut, Djordje Vasiljevic, Iris Marchal, Stefan Kempa, Altuna Akalin, Baris Tursun
Pubblicato in: Aging Cell, 2019, ISSN 1474-9718
Editore: Blackwell Publishing Inc.
DOI: 10.1111/acel.13012

MRG-1/MRG15 Is a Barrier for Germ Cell to Neuron Reprogramming in Caenorhabditis elegans

Autori: Martina Hajduskova, Gülkiz Baytek, Ena Kolundzic, Alexander Gosdschan, Marlon Kazmierczak, Andreas Ofenbauer, Maria Lena Beato del Rosal, Sergej Herzog, Nida ul Fatima, Philipp Mertins, Stefanie Seelk-Müthel, Baris Tursun
Pubblicato in: Genetics, Numero 211/1, 2019, Pagina/e 121-139, ISSN 0016-6731
Editore: Genetics Society of America
DOI: 10.1534/genetics.118.301674

HOT or not: examining the basis of high-occupancy target regions

Autori: Katarzyna Wreczycka, Vedran Franke, Bora Uyar, Ricardo Wurmus, Selman Bulut, Baris Tursun, Altuna Akalin
Pubblicato in: Nucleic Acids Research, Numero 47/11, 2019, Pagina/e 5735-5745, ISSN 0305-1048
Editore: Oxford University Press
DOI: 10.1093/nar/gkz460

Strategies for in vivo reprogramming

Autori: Andreas Ofenbauer, Baris Tursun
Pubblicato in: Current Opinion in Cell Biology, Numero 61, 2019, Pagina/e 9-15, ISSN 0955-0674
Editore: Elsevier BV
DOI: 10.1016/j.ceb.2019.06.002

Transdifferentiation: do transition states lie on the path of development?

Autori: Anna Reid, Baris Tursun
Pubblicato in: Current Opinion in Systems Biology, Numero 11, 2018, Pagina/e 18-23, ISSN 2452-3100
Editore: Elsevier
DOI: 10.1016/j.coisb.2018.07.004

Determinants of promoter and enhancer transcription directionality in metazoans

Autori: Mahmoud M. Ibrahim, Aslihan Karabacak, Alexander Glahs, Ena Kolundzic, Antje Hirsekorn, Alexa Carda, Baris Tursun, Robert P. Zinzen, Scott A. Lacadie, Uwe Ohler
Pubblicato in: Nature Communications, Numero 9/1, 2018, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-018-06962-z

Application of RNAi and Heat-shock-induced Transcription Factor Expression to Reprogram Germ Cells to Neurons in <em>C. elegans</em>

Autori: Ena Kolundzic, Stefanie Seelk, Baris Tursun
Pubblicato in: Journal of Visualized Experiments, Numero 131, 2018, ISSN 1940-087X
Editore: MYJoVE Corporation
DOI: 10.3791/56889

Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C. elegans

Autori: Thomas Wilhelm, Jonathan Byrne, Rebeca Medina, Ena Kolundžić, Johannes Geisinger, Martina Hajduskova, Baris Tursun, Holger Richly
Pubblicato in: Genes & Development, Numero 31/15, 2017, Pagina/e 1561-1572, ISSN 0890-9369
Editore: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gad.301648.117

A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large

Autori: Selma Waaijers, Javier Muñoz, Christian Berends, João J. Ramalho, Soenita S. Goerdayal, Teck Y. Low, Adja D. Zoumaro-Djayoon, Michael Hoffmann, Thijs Koorman, Roderick P. Tas, Martin Harterink, Stefanie Seelk, Jana Kerver, Casper C. Hoogenraad, Olaf Bossinger, Baris Tursun, Sander van den Heuvel, Albert J. R. Heck, Mike Boxem
Pubblicato in: BMC Biology, Numero 14/1, 2016, ISSN 1741-7007
Editore: BioMed Central
DOI: 10.1186/s12915-016-0286-x

PcG Proteins in Caenorhabditis elegans

Autori: B. Tursun
Pubblicato in: Polycomb Group Proteins, 2017, Pagina/e 289-315, ISBN 9780-128097373
Editore: Elsevier
DOI: 10.1016/b978-0-12-809737-3.00012-x

FACT sets a barrier for cell fate reprogramming in C. elegans and Human

Autori: Ena Kolundzic, Andreas Ofenbauer, Bora Uyar, Anne Sommermeier, Stefanie Seelk, Mei He, Guelkiz Baytek, Altuna Akalin, Sebastian Diecke, Scott Allen Lacadie, Baris Tursun
Pubblicato in: bioRxiv, 2017
Editore: CSHL
DOI: 10.1101/185116

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