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Design and development of advanced NAnomedicines to overcome Biological BArriers and to treat severe diseases


ESRs representative

ESRs representative nominated.


Multicellular spheroid based on a triple co-culture: A novel 3D model to mimic pancreatic tumor complexity

Autorzy: Gianpiero Lazzari, Valérie Nicolas, Michiya Matsusaki, Mitsuru Akashi, Patrick Couvreur, Simona Mura
Opublikowane w: Acta Biomaterialia, 78, 2018, Page(s) 296-307, ISSN 1742-7061
Wydawca: Elsevier BV
DOI: 10.1016/j.actbio.2018.08.008

Starch-Chitosan Polyplexes: A Versatile Carrier System for Anti-Infectives and Gene Delivery

Autorzy: Hanzey Yasar, Duy-Khiet Ho, Chiara De Rossi, Jennifer Herrmann, Sarah Gordon, Brigitta Loretz, Claus-Michael Lehr
Opublikowane w: Polymers, 10/3, 2018, Page(s) 252, ISSN 2073-4360
Wydawca: MDPI
DOI: 10.3390/polym10030252

A facile route to heterotelechelic polymer prodrug nanoparticles for imaging, drug delivery and combination therapy

Autorzy: Daniele Vinciguerra, Stéphanie Denis, Julie Mougin, Merel Jacobs, Yohann Guillaneuf, Simona Mura, Patrick Couvreur, Julien Nicolas
Opublikowane w: Journal of Controlled Release, 286, 2018, Page(s) 425-438, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2018.08.013

Advances on the formulation of proteins using nanotechnologies

Autorzy: Irene Santalices, Andrea Gonella, Dolores Torres, María José Alonso
Opublikowane w: Journal of Drug Delivery Science and Technology, 42, 2017, Page(s) 155-180, ISSN 1773-2247
Wydawca: Editions de Sante
DOI: 10.1016/j.jddst.2017.06.018

Polysaccharide Submicrocarrier for Improved Pulmonary Delivery of Poorly Soluble Anti-infective Ciprofloxacin: Preparation, Characterization, and Influence of Size on Cellular Uptake

Autorzy: Duy-Khiet Ho, Ana Costa, Chiara De Rossi, Cristiane de Souza Carvalho-Wodarz, Brigitta Loretz, Claus-Michael Lehr
Opublikowane w: Molecular Pharmaceutics, 15/3, 2018, Page(s) 1081-1096, ISSN 1543-8384
Wydawca: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.7b00967

Ultrasound-mediated drug delivery to the brain: principles, progress and prospects

Autorzy: Anshuman Dasgupta, Mengjiao Liu, Tarun Ojha, Gert Storm, Fabian Kiessling, Twan Lammers
Opublikowane w: Drug Discovery Today: Technologies, 20, 2016, Page(s) 41-48, ISSN 1740-6749
Wydawca: Elsevier BV
DOI: 10.1016/j.ddtec.2016.07.007

Telechelic polymers from reversible-deactivation radical polymerization for biomedical applications

Autorzy: Daniele Vinciguerra, Johanna Tran, Julien Nicolas
Opublikowane w: Chemical Communications, 54/3, 2018, Page(s) 228-240, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c7cc08544c

Evolution of Nanoparticle Protein Corona across the Blood–Brain Barrier

Autorzy: Alysia Cox, Patrizia Andreozzi, Roberta Dal Magro, Fabio Fiordaliso, Alessandro Corbelli, Laura Talamini, Clizia Chinello, Francesca Raimondo, Fulvio Magni, Maria Tringali, Silke Krol, Paulo Jacob Silva, Francesco Stellacci, Massimo Masserini, Francesca Re
Opublikowane w: ACS Nano, 12/7, 2018, Page(s) 7292-7300, ISSN 1936-0851
Wydawca: American Chemical Society
DOI: 10.1021/acsnano.8b03500

Phage-displayed peptides targeting specific tissues and organs

Autorzy: Josu Andrieu, Francesca Re, Laura Russo, Francesco Nicotra
Opublikowane w: Journal of Drug Targeting, 2018, Page(s) 1-11, ISSN 1061-186X
Wydawca: Taylor & Francis
DOI: 10.1080/1061186x.2018.1531419

Farnesylated Glycol Chitosan as a Platform for Drug Delivery: Synthesis, Characterization, and Investigation of Mucus–Particle Interactions

Autorzy: Duy-Khiet Ho, Sarah Frisch, Alexander Biehl, Emmanuel Terriac, Chiara De Rossi, Konrad Schwarzkopf, Franziska Lautenschläger, Brigitta Loretz, Xabier Murgia, Claus-Michael Lehr
Opublikowane w: Biomacromolecules, 19/8, 2018, Page(s) 3489-3501, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.8b00795

Sonoporation enhances liposome accumulation and penetration in tumors with low EPR

Autorzy: Benjamin Theek, Maike Baues, Tarun Ojha, Diana Möckel, Seena Koyadan Veettil, Julia Steitz, Louis van Bloois, Gert Storm, Fabian Kiessling, Twan Lammers
Opublikowane w: Journal of Controlled Release, 231, 2016, Page(s) 77-85, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2016.02.021

Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies

Autorzy: Miriam Colombo, Luisa Fiandra, Giulia Alessio, Serena Mazzucchelli, Manuela Nebuloni, Clara De Palma, Karsten Kantner, Beatriz Pelaz, Rany Rotem, Fabio Corsi, Wolfgang J. Parak, Davide Prosperi
Opublikowane w: Nature Communications, 7, 2016, Page(s) 13818, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/ncomms13818

Targeting cellular and microenvironmental multidrug resistance

Autorzy: Okan Tezcan, Tarun Ojha, Gert Storm, Fabian Kiessling, Twan Lammers
Opublikowane w: Expert Opinion on Drug Delivery, 13/9, 2016, Page(s) 1199-1202, ISSN 1742-5247
Wydawca: Ashley Publications Ltd.
DOI: 10.1080/17425247.2016.1214570

Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines

Autorzy: Gianpiero Lazzari, Patrick Couvreur, Simona Mura
Opublikowane w: Polym. Chem., 8/34, 2017, Page(s) 4947-4969, ISSN 1759-9954
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c7py00559h

Synthetic nanocarriers for the delivery of polynucleotides to the eye

Autorzy: Sofia M. Saraiva, Vanessa Castro-López, Covadonga Pañeda, María José Alonso
Opublikowane w: European Journal of Pharmaceutical Sciences, 103, 2017, Page(s) 5-18, ISSN 0928-0987
Wydawca: Elsevier BV
DOI: 10.1016/j.ejps.2017.03.001

Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors

Autorzy: Tarun Ojha, Vertika Pathak, Yang Shi, Wim E. Hennink, Chrit T.W. Moonen, Gert Storm, Fabian Kiessling, Twan Lammers
Opublikowane w: Advanced Drug Delivery Reviews, 2017, ISSN 0169-409X
Wydawca: Elsevier BV
DOI: 10.1016/j.addr.2017.07.007

Enhancing Tumor Penetration of Nanomedicines

Autorzy: Qingxue Sun, Tarun Ojha, Fabian Kiessling, Twan Lammers, Yang Shi
Opublikowane w: Biomacromolecules, 18/5, 2017, Page(s) 1449-1459, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.7b00068

Zbiory danych

MOESM2 of The synergistic effect of chlorotoxin-mApoE in boosting drug-loaded liposomes across the BBB

Autorzy: Formicola, Beatrice; Magro, Roberta Dal; Montefusco-Pereira, Carlos; Claus-Michael Lehr; Koch, Marcus; Russo, Laura; Gianvito Grasso; Deriu, Marco; Danani, Andrea; Bourdoulous, Sandrine; Re, Francesca
Opublikowane w: figshare