Molecular dissection of titin-based mechanisms in charge of cardiomyocyte dysfunction in terminal feart failure

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The summary of data generated in first 12 months of project

The summary of raw data and metadata generated in first 12 months of project

Pubblicazioni

HSPB7 is indispensable for heart development by modulating actin filament assembly

Autori: Tongbin Wu, Yongxin Mu, Julius Bogomolovas, Xi Fang, Jennifer Veevers, Roberta B. Nowak, Christopher T. Pappas, Carol C. Gregorio, Sylvia M. Evans, Velia M. Fowler, Ju Chen
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 114/45, 2017, Pagina/e 11956-11961, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1713763114

Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy

Autori: Xi Fang, Julius Bogomolovas, Tongbin Wu, Wei Zhang, Canzhao Liu, Jennifer Veevers, Matthew J. Stroud, Zhiyuan Zhang, Xiaolong Ma, Yongxin Mu, Dieu-Hung Lao, Nancy D. Dalton, Yusu Gu, Celine Wang, Michael Wang, Yan Liang, Stephan Lange, Kunfu Ouyang, Kirk L. Peterson, Sylvia M. Evans, Ju Chen
Pubblicato in: Journal of Clinical Investigation, Numero 127/8, 2017, Pagina/e 3189-3200, ISSN 0021-9738
Editore: American Society for Clinical Investigation
DOI: 10.1172/JCI94310

Infarct Fibroblasts Do Not Derive From Bone Marrow Lineages

Autori: Thomas Moore-Morris, Paola Cattaneo, Nuno Guimarães-Camboa, Julius Bogomolovas, Marta Cedenilla, Indroneal Banerjee, Mercedes Ricote, Tatiana Kisseleva, Lunfeng Zhang, Yusu Gu, Nancy D Dalton, Kirk L Peterson, Ju Chen, Michel Puceat, Sylvia M Evans
Pubblicato in: Circulation Research, 2017, Pagina/e CIRCRESAHA.117.311490, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.117.311490

Tbx20 Is Required in Mid-Gestation Cardiomyocytes and Plays a Central Role in Atrial Development

Autori: Cornelis J Boogerd, Xiaoming Zhu, Ivy Aneas, Noboru J Sakabe, Lunfeng Zhang, Debora R Sobreira, Lindsey E Montefiori, Julius Bogomolovas, Amelia C Joslin, Bin Zhou, Ju Chen, Marcelo Nobrega, Sylvia M Evans
Pubblicato in: Circulation Research, 2018, Pagina/e CIRCRESAHA.118.311339, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.118.311339

The BAG3-dependent and -independent roles of cardiac small heat shock proteins

Autori: Xi Fang, Julius Bogomolovas, Christa Trexler, Ju Chen
Pubblicato in: JCI Insight, Numero 4/4, 2019, ISSN 2379-3708
Editore: JCI Insight
DOI: 10.1172/jci.insight.126464

PKC and PKN in heart disease

Autori: Valeria Marrocco, Julius Bogomolovas, Elisabeth Ehler, Cristobal G. dos Remedios, Jiayu Yu, Chen Gao, Stephan Lange
Pubblicato in: Journal of Molecular and Cellular Cardiology, Numero 128, 2019, Pagina/e 212-226, ISSN 0022-2828
Editore: Academic Press
DOI: 10.1016/j.yjmcc.2019.01.029

Cardiac specific titin N2B exon is a novel sensitive serological marker for cardiac injury

Autori: Julius Bogomolovas, Alexander Gasch, Vilhelmas Bajoras, Dovilė Karčiauskaitė, Pranas Šerpytis, Virginija Grabauskienė, Dittmar Labeit, Siegfried Labeit
Pubblicato in: International Journal of Cardiology, Numero 212, 2016, Pagina/e 232-234, ISSN 0167-5273
Editore: Elsevier BV
DOI: 10.1016/j.ijcard.2016.03.045

A Novel Murine Model of Parvovirus Associated Dilated Cardiomyopathy Induced by Immunization with VP1-Unique Region of Parvovirus B19

Autori: Julijus Bogomolovas, Egidijus Šimoliūnas, Ieva Rinkūnaitė, Luka Smalinskaitė, Andrej Podkopajev, Daiva Bironaitė, Cleo-Aron Weis, Alexander Marx, Virginija Bukelskienė, Norbert Gretz, Virginija Grabauskienė, Dittmar Labeit, Siegfried Labeit
Pubblicato in: BioMed Research International, Numero 2016, 2016, Pagina/e 1-9, ISSN 2314-6133
Editore: Hindawi Publishing Corporation
DOI: 10.1155/2016/1627184

CARP interacts with titin at a unique helical N2A sequence and at the domain Ig81 to form a structured complex

Autori: Tiankun Zhou, Jennifer R. Fleming, Barbara Franke, Julius Bogomolovas, Igor Barsukov, Daniel J. Rigden, Siegfried Labeit, Olga Mayans
Pubblicato in: FEBS Letters, Numero 590/18, 2016, Pagina/e 3098-3110, ISSN 0014-5793
Editore: Elsevier BV
DOI: 10.1002/1873-3468.12362

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