Molecular dissection of titin-based mechanisms in charge of cardiomyocyte dysfunction in terminal feart failure

Rezultaty

The summary of data generated in first 12 months of project

The summary of raw data and metadata generated in first 12 months of project

Publikacje

HSPB7 is indispensable for heart development by modulating actin filament assembly

Autorzy: Tongbin Wu, Yongxin Mu, Julius Bogomolovas, Xi Fang, Jennifer Veevers, Roberta B. Nowak, Christopher T. Pappas, Carol C. Gregorio, Sylvia M. Evans, Velia M. Fowler, Ju Chen
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 114/45, 2017, Strona(/y) 11956-11961, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1713763114

Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy

Autorzy: Xi Fang, Julius Bogomolovas, Tongbin Wu, Wei Zhang, Canzhao Liu, Jennifer Veevers, Matthew J. Stroud, Zhiyuan Zhang, Xiaolong Ma, Yongxin Mu, Dieu-Hung Lao, Nancy D. Dalton, Yusu Gu, Celine Wang, Michael Wang, Yan Liang, Stephan Lange, Kunfu Ouyang, Kirk L. Peterson, Sylvia M. Evans, Ju Chen
Opublikowane w: Journal of Clinical Investigation, Numer 127/8, 2017, Strona(/y) 3189-3200, ISSN 0021-9738
Wydawca: American Society for Clinical Investigation
DOI: 10.1172/JCI94310

Infarct Fibroblasts Do Not Derive From Bone Marrow Lineages

Autorzy: Thomas Moore-Morris, Paola Cattaneo, Nuno Guimarães-Camboa, Julius Bogomolovas, Marta Cedenilla, Indroneal Banerjee, Mercedes Ricote, Tatiana Kisseleva, Lunfeng Zhang, Yusu Gu, Nancy D Dalton, Kirk L Peterson, Ju Chen, Michel Puceat, Sylvia M Evans
Opublikowane w: Circulation Research, 2017, Strona(/y) CIRCRESAHA.117.311490, ISSN 0009-7330
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.117.311490

Tbx20 Is Required in Mid-Gestation Cardiomyocytes and Plays a Central Role in Atrial Development

Autorzy: Cornelis J Boogerd, Xiaoming Zhu, Ivy Aneas, Noboru J Sakabe, Lunfeng Zhang, Debora R Sobreira, Lindsey E Montefiori, Julius Bogomolovas, Amelia C Joslin, Bin Zhou, Ju Chen, Marcelo Nobrega, Sylvia M Evans
Opublikowane w: Circulation Research, 2018, Strona(/y) CIRCRESAHA.118.311339, ISSN 0009-7330
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.118.311339

The BAG3-dependent and -independent roles of cardiac small heat shock proteins

Autorzy: Xi Fang, Julius Bogomolovas, Christa Trexler, Ju Chen
Opublikowane w: JCI Insight, Numer 4/4, 2019, ISSN 2379-3708
Wydawca: JCI Insight
DOI: 10.1172/jci.insight.126464

PKC and PKN in heart disease

Autorzy: Valeria Marrocco, Julius Bogomolovas, Elisabeth Ehler, Cristobal G. dos Remedios, Jiayu Yu, Chen Gao, Stephan Lange
Opublikowane w: Journal of Molecular and Cellular Cardiology, Numer 128, 2019, Strona(/y) 212-226, ISSN 0022-2828
Wydawca: Academic Press
DOI: 10.1016/j.yjmcc.2019.01.029

Cardiac specific titin N2B exon is a novel sensitive serological marker for cardiac injury

Autorzy: Julius Bogomolovas, Alexander Gasch, Vilhelmas Bajoras, Dovilė Karčiauskaitė, Pranas Šerpytis, Virginija Grabauskienė, Dittmar Labeit, Siegfried Labeit
Opublikowane w: International Journal of Cardiology, Numer 212, 2016, Strona(/y) 232-234, ISSN 0167-5273
Wydawca: Elsevier BV
DOI: 10.1016/j.ijcard.2016.03.045

A Novel Murine Model of Parvovirus Associated Dilated Cardiomyopathy Induced by Immunization with VP1-Unique Region of Parvovirus B19

Autorzy: Julijus Bogomolovas, Egidijus Šimoliūnas, Ieva Rinkūnaitė, Luka Smalinskaitė, Andrej Podkopajev, Daiva Bironaitė, Cleo-Aron Weis, Alexander Marx, Virginija Bukelskienė, Norbert Gretz, Virginija Grabauskienė, Dittmar Labeit, Siegfried Labeit
Opublikowane w: BioMed Research International, Numer 2016, 2016, Strona(/y) 1-9, ISSN 2314-6133
Wydawca: Hindawi Publishing Corporation
DOI: 10.1155/2016/1627184

CARP interacts with titin at a unique helical N2A sequence and at the domain Ig81 to form a structured complex

Autorzy: Tiankun Zhou, Jennifer R. Fleming, Barbara Franke, Julius Bogomolovas, Igor Barsukov, Daniel J. Rigden, Siegfried Labeit, Olga Mayans
Opublikowane w: FEBS Letters, Numer 590/18, 2016, Strona(/y) 3098-3110, ISSN 0014-5793
Wydawca: Elsevier BV
DOI: 10.1002/1873-3468.12362

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