Transforming the future of agriculture through synthetic photorespiration

Risultati finali

At least one synthetic pathway fully operational in E. coli

At least one synthetic pathway fully operating using purified enzymes

A computational model of plant photosynthesis and metabolism that demonstrates the expected effect of the synthetic pathways on the rate of photosynthesis and carbon fixation.

Synthetic pathways in cyanobacteria

At least one synthetic pathway that is fully active in cyanobacteria

Phenotypes of transgenic plant

Photosynthetic rate growth rate and other physiological characteristics of at least one modified plant that expresses a synthetic pathway

In vitro optimized pathways

Pathway optimization that includes catalytic efficiency stability andor localization of the different enzyme eg scaffolding

Project website

Publication of the website of the project (public pages).

Pubblicazioni

Sulfur-Oxidizing Symbionts without Canonical Genes for Autotrophic CO 2 Fixation

Autori: Brandon K. B. Seah, Chakkiath Paul Antony, Bruno Huettel, Jan Zarzycki, Lennart Schada von Borzyskowski, Tobias J. Erb, Angela Kouris, Manuel Kleiner, Manuel Liebeke, Nicole Dubilier, Harald R. Gruber-Vodicka
Pubblicato in: mBio, Numero 10/3, 2019, ISSN 2150-7511
Editore: American Society for Microbiology
DOI: 10.1128/mbio.01112-19

A short history of RubisCO: the rise and fall (?) of Nature's predominant CO 2 fixing enzyme

Autori: Tobias J Erb, Jan Zarzycki
Pubblicato in: Current Opinion in Biotechnology, Numero 49, 2018, Pagina/e 100-107, ISSN 0958-1669
Editore: Elsevier BV
DOI: 10.1016/j.copbio.2017.07.017

Synthetic metabolism: metabolic engineering meets enzyme design

Autori: Tobias J Erb, Patrik R Jones, Arren Bar-Even
Pubblicato in: Current Opinion in Chemical Biology, Numero 37, 2017, Pagina/e 56-62, ISSN 1367-5931
Editore: Elsevier BV
DOI: 10.1016/j.cbpa.2016.12.023

Daring metabolic designs for enhanced plant carbon fixation

Autori: Arren Bar-Even
Pubblicato in: Plant Science, Numero 273, 2018, Pagina/e 71-83, ISSN 0168-9452
Editore: Elsevier BV
DOI: 10.1016/j.plantsci.2017.12.007

Enzyme engineering: reaching the maximal catalytic efficiency peak

Autori: Moshe Goldsmith, Dan S Tawfik
Pubblicato in: Current Opinion in Structural Biology, Numero 47, 2017, Pagina/e 140-150, ISSN 0959-440X
Editore: Elsevier BV
DOI: 10.1016/j.sbi.2017.09.002

Biochemical and synthetic biology approaches to improve photosynthetic CO2-fixation

Autori: Tobias J Erb, Jan Zarzycki
Pubblicato in: Current Opinion in Chemical Biology, Numero 34, 2016, Pagina/e 72-79, ISSN 1367-5931
Editore: Elsevier BV
DOI: 10.1016/j.cbpa.2016.06.026

Design and in vitro realization of carbon-conserving photorespiration

Autori: Devin L. Trudeau, Christian Edlich-Muth, Jan Zarzycki, Marieke Scheffen, Moshe Goldsmith, Olga Khersonsky, Ziv Avizemer, Sarel J. Fleishman, Charles A. R. Cotton, Tobias J. Erb, Dan S. Tawfik, Arren Bar-Even
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 115/49, 2018, Pagina/e E11455-E11464, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1812605115

Synthetic biology approaches for improving photosynthesis

Autori: Armin Kubis, Arren Bar-Even
Pubblicato in: Journal of Experimental Botany, Numero 70/5, 2019, Pagina/e 1425-1433, ISSN 0022-0957
Editore: Oxford University Press
DOI: 10.1093/jxb/erz029

A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation

Autori: Marieke Scheffen, Daniel G. Marchal, Thomas Beneyton, Sandra K. Schuller, Melanie Klose, Christoph Diehl, Jessica Lehmann, Pascal Pfister, Martina Carrillo, Hai He, Selçuk Aslan, Niña S. Cortina, Peter Claus, Daniel Bollschweiler, Jean-Christophe Baret, Jan M. Schuller, Jan Zarzycki, Arren Bar-Even, Tobias J. Erb
Pubblicato in: Nature Catalysis, 2021, ISSN 2520-1158
Editore: Springer Nature
DOI: 10.1038/s41929-020-00557-y

Risultati finali

Pubblicazioni

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