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Transforming the future of agriculture through synthetic photorespiration

Rezultaty

Synthetic pathways in E. coli

At least one synthetic pathway fully operational in E. coli

In vitro reconstructed pathways

At least one synthetic pathway fully operating using purified enzymes

Model of plant photosynthesis

A computational model of plant photosynthesis and metabolism that demonstrates the expected effect of the synthetic pathways on the rate of photosynthesis and carbon fixation.

Synthetic pathways in cyanobacteria

At least one synthetic pathway that is fully active in cyanobacteria

Phenotypes of transgenic plant

Photosynthetic rate growth rate and other physiological characteristics of at least one modified plant that expresses a synthetic pathway

In vitro optimized pathways

Pathway optimization that includes catalytic efficiency stability andor localization of the different enzyme eg scaffolding

Project website

Publication of the website of the project (public pages).

Publikacje

Sulfur-Oxidizing Symbionts without Canonical Genes for Autotrophic CO 2 Fixation

Autorzy: Brandon K. B. Seah, Chakkiath Paul Antony, Bruno Huettel, Jan Zarzycki, Lennart Schada von Borzyskowski, Tobias J. Erb, Angela Kouris, Manuel Kleiner, Manuel Liebeke, Nicole Dubilier, Harald R. Gruber-Vodicka
Opublikowane w: mBio, Numer 10/3, 2019, ISSN 2150-7511
Wydawca: American Society for Microbiology
DOI: 10.1128/mbio.01112-19

A short history of RubisCO: the rise and fall (?) of Nature's predominant CO 2 fixing enzyme

Autorzy: Tobias J Erb, Jan Zarzycki
Opublikowane w: Current Opinion in Biotechnology, Numer 49, 2018, Strona(/y) 100-107, ISSN 0958-1669
Wydawca: Elsevier BV
DOI: 10.1016/j.copbio.2017.07.017

Synthetic metabolism: metabolic engineering meets enzyme design

Autorzy: Tobias J Erb, Patrik R Jones, Arren Bar-Even
Opublikowane w: Current Opinion in Chemical Biology, Numer 37, 2017, Strona(/y) 56-62, ISSN 1367-5931
Wydawca: Elsevier BV
DOI: 10.1016/j.cbpa.2016.12.023

Daring metabolic designs for enhanced plant carbon fixation

Autorzy: Arren Bar-Even
Opublikowane w: Plant Science, Numer 273, 2018, Strona(/y) 71-83, ISSN 0168-9452
Wydawca: Elsevier BV
DOI: 10.1016/j.plantsci.2017.12.007

Enzyme engineering: reaching the maximal catalytic efficiency peak

Autorzy: Moshe Goldsmith, Dan S Tawfik
Opublikowane w: Current Opinion in Structural Biology, Numer 47, 2017, Strona(/y) 140-150, ISSN 0959-440X
Wydawca: Elsevier BV
DOI: 10.1016/j.sbi.2017.09.002

Biochemical and synthetic biology approaches to improve photosynthetic CO2-fixation

Autorzy: Tobias J Erb, Jan Zarzycki
Opublikowane w: Current Opinion in Chemical Biology, Numer 34, 2016, Strona(/y) 72-79, ISSN 1367-5931
Wydawca: Elsevier BV
DOI: 10.1016/j.cbpa.2016.06.026

Design and in vitro realization of carbon-conserving photorespiration

Autorzy: Devin L. Trudeau, Christian Edlich-Muth, Jan Zarzycki, Marieke Scheffen, Moshe Goldsmith, Olga Khersonsky, Ziv Avizemer, Sarel J. Fleishman, Charles A. R. Cotton, Tobias J. Erb, Dan S. Tawfik, Arren Bar-Even
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 115/49, 2018, Strona(/y) E11455-E11464, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1812605115

Synthetic biology approaches for improving photosynthesis

Autorzy: Armin Kubis, Arren Bar-Even
Opublikowane w: Journal of Experimental Botany, Numer 70/5, 2019, Strona(/y) 1425-1433, ISSN 0022-0957
Wydawca: Oxford University Press
DOI: 10.1093/jxb/erz029

A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation

Autorzy: Marieke Scheffen, Daniel G. Marchal, Thomas Beneyton, Sandra K. Schuller, Melanie Klose, Christoph Diehl, Jessica Lehmann, Pascal Pfister, Martina Carrillo, Hai He, Selçuk Aslan, Niña S. Cortina, Peter Claus, Daniel Bollschweiler, Jean-Christophe Baret, Jan M. Schuller, Jan Zarzycki, Arren Bar-Even, Tobias J. Erb
Opublikowane w: Nature Catalysis, 2021, ISSN 2520-1158
Wydawca: Springer Nature
DOI: 10.1038/s41929-020-00557-y

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