Cohesin-mediated chromosomal looping: From linear paths to 3D effects

Project Information

CohesinLooping

Grant agreement ID: 772471

DOI

10.3030/772471

Project closed

EC signature date 6 February 2018

Start date 1 April 2018

End date 31 March 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 998 375,00

EU contribution

€ 1 998 375,00

Coordinated by

STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data management plan

A data managemnet plan will be written as part of the pilot on open research data

Publications

Peer reviewed articles (6)

The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism

Author(s): Marjon S. van Ruiten, Démi van Gent, Ángela Sedeño Cacciatore, Astrid Fauster, Laureen Willems, Maarten L. Hekkelman, Liesbeth Hoekman, Maarten Altelaar, Judith H. I. Haarhuis, Thijn R. Brummelkamp, Elzo de Wit & Benjamin D. Rowland
Published in: Nature Structural & Molecular Biology, Issue 29, 2022, Page(s) 586–591, ISSN 1545-9985
Publisher: Springer - Nature
DOI: 10.1038/s41594-022-00773-z

3D genomics across the tree of life reveals condensin II as a determinant of architecture type

Author(s): Claire Hoencamp, Olga Dudchenko, Ahmed M. O. Elbatsh, Sumitabha Brahmachari, Jonne A. Raaijmakers, Tom van Schaik, Ángela Sedeño Cacciatore, Vinícius G. Contessoto, Roy G. H. P. van Heesbeen, Bram van den Broek, Aditya N. Mhaskar, Hans Teunissen, Brian Glenn St Hilaire, David Weisz, Arina D. Omer, Melanie Pham, Zane Colaric, Zhenzhen Yang, Suhas S. P. Rao, Namita Mitra, Christopher Lui, Weijie
Published in: Science, Issue 372/6545, 2021, Page(s) 984-989, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abe2218

Structural basis of centromeric cohesion protection

Author(s): Alberto García-Nieto, Amrita Patel, Yan Li, Roel Oldenkamp, Leonardo Feletto, Joshua J. Graham, Laureen Willems, Kyle W. Muir, Daniel Panne, Benjamin D. Rowland
Published in: Nature Structural & Molecular Biology, Issue 853-859, 2023, Page(s) 853-859, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-023-00968-y

A Mediator-cohesin axis controls heterochromatin domain formation

Author(s): Judith H. I. Haarhuis, Robin H. van der Weide, Vincent A. Blomen, Koen D. Flach, Hans Teunissen, Laureen Willems, Thijn R. Brummelkamp, Benjamin D. Rowland & Elzo de Wit
Published in: Nature Communications, Issue 13/754, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-28377-7

The structural basis for cohesin–CTCF-anchored loops

Author(s): Yan Li, Judith H. I. Haarhuis, Ángela Sedeño Cacciatore, Roel Oldenkamp, Marjon S. van Ruiten, Laureen Willems, Hans Teunissen, Kyle W. Muir, Elzo de Wit, Benjamin D. Rowland, Daniel Panne
Published in: Nature, Issue 578/7795, 2020, Page(s) 472-476, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-019-1910-z

Hi-C analyses with GENOVA: a case study with cohesin variants

Author(s): Robin H van der Weide, Teun van den Brand, Judith H I Haarhuis, Hans Teunissen, Benjamin D Rowland, Elzo de Wit
Published in: NAR Genomics and Bioinformatics, Issue 3/2, 2021, ISSN 2631-9268
Publisher: Oxford University Press
DOI: 10.1093/nargab/lqab040