Chiroptical, optical and magnetic probes for protein sensing based on cage metal complexes

Informazioni relative al progetto

CLATHROPROBES

ID dell’accordo di sovvenzione: 778245

DOI

10.3030/778245

Progetto chiuso

Data della firma CE 17 Ottobre 2017

Data di avvio 1 Gennaio 2018

Data di completamento 31 Dicembre 2023

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 855 000,00

Contributo UE

€ 796 500,00

Coordinato da

UNIWERSYTET WROCLAWSKI
Poland

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Websites, patent fillings, videos etc. (4)

Three research paper on the topic of WP3
Internet website of the project

Internet website highlighting the research activity of the project and providing information about its progress

Three research papers on the topic of WP2
Two research papers on the topic of WP1

Pubblicazioni

Peer reviewed articles (25)

Spectroelectrochemical Properties and Catalytic Activity in Cyclohexane Oxidation of the Hybrid Zr/Hf-Phthalocyaninate-Capped Nickel(II) and Iron(II) tris-Pyridineoximates and Their Precursors

Autori: Yan Z. Voloshin; Semyon V. Dudkin; Svetlana A. Belova; Daniel Gherca; Dumitru Samohvalov; Corina-Mihaela Manta; Maria-Andreea Lungan; Samuel M. Meier-Menches; Peter Rapta; Denisa Darvasiová; Michal Malček; Armando J. L. Pombeiro; Luísa M. D. R. S. Martins; Vladimir B. Arion
Pubblicato in: Molecules, Numero 26 (17), 2021, Pagina/e 336, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules26020336

Crystal structure and Hirshfeld surface analysis of poly[[bis-[μ4-N,N'-(1,3,5-oxadiazinane-3,5-di-yl)bis(carbamoyl-methano-ato)]nickel(II)tetra-potassium] 4.8-hydrate]

Autori: Maksym O. Plutenko; Matti Haukka; Alina O. Husak; Turganbay S. Iskenderov; Nurullo U. Mulloev
Pubblicato in: Acta Crystallographica Section E: Crystallographic Communications, Numero 2, 2021, Pagina/e 298-304, ISSN 2056-9890
Editore: International Union of Crystallography
DOI: 10.1107/s205698902100205x

Tumor-Specific Reactive Oxygen Species Accelerators Improve Chimeric Antigen Receptor T Cell Therapy in B Cell Malignancies

Autori: Hyeon Joo Yoo, Yibin Liu, Lei Wang, Maria-Luisa Schubert, Jean-Marc Hoffmann, Sanmei Wang, Brigitte Neuber, Angela Hückelhoven-Krauss, Ulrike Gern, Anita Schmitt, Carsten Müller-Tidow, Peter Dreger, Andriy Mokhir, Michael Schmitt, Leopold Sellner
Pubblicato in: International Journal of Molecular Sciences, Numero 20/10, 2019, Pagina/e 2469, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20102469

Inhibition of DNA synthesis in the transcription system of Taq DNA polymerase by various iron and cobalt(II) tris-dioximate clathrochelates: In vitro study and X-ray structure of leader inhibitors, the carboxyl-terminated macrobicyclic complexes☆

Autori: Oleg A. Varzatskii, Anna V. Vologzhanina, Valentin V. Novikov, Serhii V. Vakarov, Ruslan V. Oblap, Yan Z. Voloshin
Pubblicato in: Inorganica Chimica Acta, Numero 482, 2018, Pagina/e 90-98, ISSN 0020-1693
Editore: Elsevier BV
DOI: 10.1016/j.ica.2018.06.004

3D-Shaped Binders of Unfolded Proteins Inducing Cancer Cell-Specific Endoplasmic Reticulum Stress In Vitro and In Vivo

Autori: Insa Klemt; Oleg Varzatskii; Roman Selin; Serhii Vakarov; Vladyslava Kovalska; Galyna Bila; Rostyslav Bilyy; Yan Voloshin; Itziar Cossío Cuartero; Andrés Hidalgo; Benjamin Frey; Ina Becker; Bernhard Friedrich; Rainer Tietze; Ralf P. Friedrich; Christoph Alexiou; Elena-Laura Ursu; Alexandru Rotaru; Iris Solymosi; M. Eugenia Pérez-Ojeda; Andriy Mokhir
Pubblicato in: J. Am. Chem. Soc., Numero 145 (40), 2023, Pagina/e 22252-22264, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.3c08827

A cancer specific oxaliplatin-releasing Pt( iv )-prodrug

Autori: Viktor Reshetnikov, Anton Arkhypov, Purushottam Reddy Julakanti, Andriy Mokhir
Pubblicato in: Dalton Transactions, Numero 47/19, 2018, Pagina/e 6679-6682, ISSN 1477-9226
Editore: Royal Society of Chemistry
DOI: 10.1039/c8dt01458b

Crystal structure and Hirshfeld surface analysis of poly[[tetraaqua(μ-1,3,4,7,8,10,12,13,16,17,19,22-dodecaazatetracyclo[8.8.4.1^3,17.1^8,12]tetracosane-5,6,14,15,20,21-hexaonato)iron(IV)dilithium] tetrahydrate]

Autori: Maksym O. Plutenko; Sergiu Shova; Vadim A. Pavlenko; Irina A. Golenya; Igor O. Fritsky
Pubblicato in: Acta Crystallographica Section E: Crystallographic Commun., Numero E79, 2023, Pagina/e 1059-1062, ISSN 2056-9890
Editore: International Union of Crystallography
DOI: 10.1107/s2056989023008587

Induced chirality of cage metal complexes switched by their supramolecular and covalent binding

Autori: Vladyslava B. Kovalska, Serhii V. Vakarov, Marina V. Kuperman, Mykhaylo Y. Losytskyy, Elzbieta Gumienna-Kontecka, Yan Z. Voloshin, Oleg A. Varzatskii
Pubblicato in: Dalton Transactions, Numero 47/4, 2018, Pagina/e 1036-1052, ISSN 1477-9226
Editore: Royal Society of Chemistry
DOI: 10.1039/c7dt03731g

Chemical Tools for Targeted Amplification of Reactive Oxygen Species in Neutrophils

Autori: Viktor Reshetnikov, Jonas Hahn, Christian Maueröder, Christine Czegley, Luis Enrique Munoz, Martin Herrmann, Markus H. Hoffmann, Andriy Mokhir
Pubblicato in: Frontiers in Immunology, Numero 9, 2018, Pagina/e 1827, ISSN 1664-3224
Editore: FrontiersMediaSA
DOI: 10.3389/fimmu.2018.01827

Synthesis and characterization of an Fe( i ) cage complex with high stability towards strong H-acids

Autori: Yan Z. Voloshin, Valentin V. Novikov, Yulia V. Nelyubina, Alexander S. Belov, Dmitrii M. Roitershtein, Anton Savitsky, Andriy Mokhir, Jörg Sutter, Matthias E. Miehlich, Karsten Meyer
Pubblicato in: Chemical Communications, Numero 54/28, 2018, Pagina/e 3436-3439, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/c7cc09611a

Extension and functionalization of an encapsulating macrobicyclic ligand using palladium-catalyzed Suzuki–Miyaura and Sonogashira reactions of iron( ii ) dihalogenoclathrochelates with inherent halogen substituents

Autori: Irina N. Denisenko, Oleg A. Varzatskii, Roman A. Selin, Alexander S. Belov, Ekaterina G. Lebed, Anna V. Vologzhanina, Yan V. Zubavichus, Yan Z. Voloshin
Pubblicato in: RSC Advances, Numero 8/24, 2018, Pagina/e 13578-13587, ISSN 2046-2069
Editore: Royal Society of Chemistry
DOI: 10.1039/c8ra01819g

The molecular design of cage metal complexes for biological applications: pathways of the synthesis, and X-ray structures of a series of new N 2 -, S 2 - and O 2 -alicyclic iron( ii ) di- and tetrachloroclathrochelates

Autori: Genrikh E. Zelinskii, Alexander S. Belov, Irina G. Belaya, Anna V. Vologzhanina, Valentin V. Novikov, Oleg A. Varzatskii, Yan Z. Voloshin
Pubblicato in: New Journal of Chemistry, Numero 42/1, 2018, Pagina/e 56-66, ISSN 1144-0546
Editore: Royal Society of Chemistry
DOI: 10.1039/c7nj03051g

Very Large Magnetic Anisotropy of Cage Cobalt(II) Complexes with a Rigid Cholesteryl Substituent from Paramagnetic NMR Spectroscopy

Autori: Alexander A. Pavlov, Svetlana A. Savkina, Alexander S. Belov, Yan Z. Voloshin, Yulia V. Nelyubina, Valentin V. Novikov
Pubblicato in: ACS Omega, Numero 3/5, 2018, Pagina/e 4941-4946, ISSN 2470-1343
Editore: American Chemical Society
DOI: 10.1021/acsomega.8b00772

Efficient visible light-driven water oxidation catalysed by an iron( iv ) clathrochelate complex

Autori: Sergii I. Shylin, Mariia V. Pavliuk, Luca D’Amario, Fikret Mamedov, Jacinto Sá, Gustav Berggren, Igor O. Fritsky
Pubblicato in: Chemical Communications, Numero 55/23, 2019, Pagina/e 3335-3338, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/c9cc00229d

Induced CD of iron( ii ) clathrochelates: sensing of the structural and conformational alterations of serum albumins

Autori: Vladyslava Kovalska, Marina Kuperman, Mykhaylo Losytskyy, Serhii Vakarov, Slawomir Potocki, Sergiy Yarmoluk, Yan Voloshin, Oleg Varzatskii, Elzbieta Gumienna-Kontecka
Pubblicato in: Metallomics, Numero 11/2, 2019, Pagina/e 338-348, ISSN 1756-5901
Editore: Royal Society of Chemistry
DOI: 10.1039/c8mt00278a

Photoinduced hole transfer from tris(bipyridine)ruthenium dye to a high-valent iron-based water oxidation catalyst

Autori: Sergii I. Shylin, Mariia V. Pavliuk, Luca D’Amario, Igor O. Fritsky, Gustav Berggren
Pubblicato in: Faraday Discussions, Numero 215, 2019, Pagina/e 162-174, ISSN 1359-6640
Editore: Royal Society of Chemistry
DOI: 10.1039/c8fd00167g

Dicarboxyl-terminated iron( ii ) clathrochelates as ICD-reporters for globular proteins

Autori: Vladyslava Kovalska, Serhii Vakarov, Mykhaylo Losytskyy, Marina Kuperman, Nina Chornenka, Yuliya Toporivska, Elzbieta Gumienna-Kontecka, Yan Voloshin, Oleg Varzatskii, Andriy Mokhir
Pubblicato in: RSC Advances, Numero 9/42, 2019, Pagina/e 24218-24230, ISSN 2046-2069
Editore: Royal Society of Chemistry
DOI: 10.1039/c9ra04102h

Chemical design of the heterodifunctionalized iron(II) clathrochelates with terminal biorelevant carboxyl group and reactive triple C≡C bond: Synthesis, structure, redox properties and their stability in various media

Autori: Roman A. Selin, Nina V. Chornenka, Viktor Ya. Chernii, Andriy Mokhir, Anna V. Vologzhanina, Alexander S. Belov, Alexander L. Pomadchik, Yan Z. Voloshin
Pubblicato in: Inorganica Chimica Acta, Numero 496, 2019, Pagina/e 119047, ISSN 0020-1693
Editore: Elsevier BV
DOI: 10.1016/j.ica.2019.119047

Pseudomacrobicyclic Phthalocyaninate-Capped Cobalt(III) tris-Pyridineoximates: Template Synthesis, X-Ray Structure and Spectral Characteristics

Autori: Svetlana A. Belova (Savkina), Semyon V. Dudkin, Alexander S. Belov, Yulia V. Nelyubina, Valentin V. Novikov, Yan V. Zubavichus, Yan Z. Voloshin
Pubblicato in: Macroheterocycles, Numero 12/2, 2019, Pagina/e 193-197, ISSN 1998-9539
Editore: Ivanovo State University of Chemistry and Technology
DOI: 10.6060/mhc190550d

Sensing of Proteins by ICD Response of Iron(II) Clathrochelates Functionalized by Carboxyalkylsulfide Groups

Autori: Mykhaylo Losytskyy, Nina Chornenka, Serhii Vakarov, Samuel M. Meier-Menches, Christopher Gerner, Slawomir Potocki, Vladimir B. Arion, Elzbieta Gumienna-Kontecka, Yan Voloshin, Vladyslava Kovalska
Pubblicato in: Biomolecules, Numero 10/12, 2020, Pagina/e 1602, ISSN 2218-273X
Editore: MDPI
DOI: 10.3390/biom10121602

SYNTHESIS OF MODYFIED FLUORESCEINE FOR CLICK REACTIONS

Autori: Roman Selin, Viktor Chernii, Andriy Mokhir
Pubblicato in: Ukrainian Chemistry Journal, Numero 86/3, 2020, Pagina/e 3-8, ISSN 0041-6045
Editore: National'na Akademiya Nauk Ukrainy
DOI: 10.33609/0041-6045.86.3.2020.3-8

Esterification vs. 1,3-Dipolar Cycloaddition Synthetic Approaches for Preparation of the Fluorescently Labelled Iron(II) Clathrochelates

Autori: R.A. Selin, V.Y. Chernii, D.V. Kryvorotenko, A. Mokhir, Y.Z. Voloshin
Pubblicato in: Macroheterocycles, Numero 14(1), 2021, Pagina/e 94-100, ISSN 1998-9539
Editore: Ivanovo State University of Chemistry and Technology
DOI: 10.6060/mhc201230v

Expanding manganese(IV) aqueous chemistry: unusually stable water-soluble hexahydrazide clathrochelate complexes

Autori: Sergii I. Shylin; Sergii I. Shylin; James Pogrebetsky; Alina O. Husak; Dmytro Bykov; Andriy Mokhir; Frank Hampel; Sergiu Shova; Andrew Ozarowski; Elzbieta Gumienna-Kontecka; Igor O. Fritsky
Pubblicato in: Chemical Communications, Numero 57 (84), 2021, Pagina/e 11060-11063, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/d1cc04870h

Crystal structure of a water oxidation catalyst solvate with composition (NH4)2[FeIV(L-6H)]·- 3CH3COOH (L = clathrochelate ligand)

Autori: Plutenko, Maksym O.; Shylin, Sergii I.; Shova, Sergiu; Blinder, Aleksander V.; Fritsky, Igor O.
Pubblicato in: Acta Crystallographica Section E: Crystallographic Commun., Numero E80, 2024, Pagina/e 25-28, ISSN 2056-9890
Editore: International Union of Crystallography
DOI: 10.1107/S2056989023010514

Synthesis and spectral characterization of the first fluorescein-tagged iron(II) clathrochelates, their supramolecular interactions with globular proteins, and cellular uptake

Autori: Roman O. Selin; Insa Klemt; Viktor Chernii; Mykhaylo Yu. Losytskyy; Svitlana Chernii; Andrzej Mular; Elzbieta Gumienna-Kontecka; Vladyslava B. Kovalska; Yan Z. Voloshin; Anna V. Vologzhanina; Pavel V. Dorovatovskii; Andriy Mokhir
Pubblicato in: RSC ADVANCES, Numero 6, 2021, Pagina/e 8163-8177, ISSN 2046-2069
Editore: Royal Society of Chemistry
DOI: 10.1039/d0ra10502c