Genetics of Individuality

Información del proyecto

IndiGene

Identificador del acuerdo de subvención: 810172

DOI 10.3030/810172

Fecha de la firma de la CE 18 Enero 2019

Fecha de inicio 1 Febrero 2019

Fecha de finalización 31 Julio 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total € 6 272 613,00

Aportación de la UE € 6 272 613,00

Coordinado por

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany

Resultado final

Open Research Data Pilot (1)

Data Management Plan

Data Management Plan for the Open Research Data Pilot

Publicaciones

Peer reviewed articles (8)

Genomic variations and epigenomic landscape of the Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel

Autores: Adrien Leger, Ian Brettell, Jack Monahan, Carl Barton, Nadeshda Wolf, Natalja Kusminski, Cathrin Herder, Narendar Aadepu, Clara Becker, Jakob Gierten, Omar T. Hammouda, Eva Hasel, Colin Lischik, Katharina Lust, Natalia Sokolova, Risa Suzuki, Tinatini Tavhelidse, Thomas Thumberger, Erika Tsingos, Philip Watson, Bettina Welz, Kiyoshi Naruse, Felix Loosli, Joachim Wittbrodt, Ewan Birney & Tomas Fitzg
Publicado en: Genome Biology, Edición 23, Article number: 58, 2022, ISSN 1474-760X
Editor: Springer Nature
DOI: 10.1186/s13059-022-02602-4

Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development

Autores: Lucie Zilova, Venera Weinhardt, Tinatini Tavhelidse, Christina Schlagheck, Thomas Thumberger, Joachim Wittbrodt
Publicado en: eLife, Edición 10, 2021, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.66998

Boosting targeted genome editing using the hei-tag

Autores: Thomas ThumbergerTinatini Tavhelidse-SuckJose Arturo Gutierrez-TrianaAlex CorneanRebekka MedertBettina WelzMarc FreichelJoachim Wittbrodt
Publicado en: eLife, 2022, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.70558

The Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel

Autores: Tomas Fitzgerald, Ian Brettell, Adrien Leger, Nadeshda Wolf, Natalja Kusminski, Jack Monahan, Carl Barton, Cathrin Herder, Narendar Aadepu, Jakob Gierten, Clara Becker, Omar T. Hammouda, Eva Hasel, Colin Lischik, Katharina Lust, Natalia Sokolova, Risa Suzuki, Erika Tsingos, Tinatini Tavhelidse, Thomas Thumberger, Philip Watson, Bettina Welz, Nadia Khouja, Kiyoshi Naruse, Ewan Birney, Joachim Wittb
Publicado en: Genome Biology, Edición 23, Article number: 59, 2022, ISSN 1474-760X
Editor: Springer Nature
DOI: 10.1186/s13059-022-02623-z

Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions

Autores: Jakob Gierten, Christian Pylatiuk, Omar T. Hammouda, Christian Schock, Johannes Stegmaier, Joachim Wittbrodt, Jochen Gehrig, Felix Loosli
Publicado en: Scientific Reports, Edición 10/1, 2020, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-020-58563-w

De novo PAM generation to reach initially inaccessible target sites for base editing

Autores: Kaisa Pakari, Joachim Wittbrodt, Joachim Wittbrodt
Publicado en: Development, 2023, ISSN 0950-1991
Editor: The Company of Biologists Ltd.
DOI: 10.1242/dev.201115

CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart disease

Autores: Lino Doering, Alex Cornean, Thomas Thumberger, Joergen Benjaminsen, Beate Wittbrodt, Tanja Kellner, Omar T. Hammouda, Matthias Gorenflo, Joachim Wittbrodt and Jakob Gierten
Publicado en: | Disease Models & Mechanisms, 2023, ISSN 1754-8403
Editor: The Company of Biologists Ltd.
DOI: 10.1242/dmm.049811

Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction

Autores: Alex Cornean, Jakob Gierten, Bettina Welz, Juan Luis Mateo, Thomas Thumberger, Joachim Wittbrodt
Publicado en: eLife, 2022, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.72124