Genetics of Individuality

Project Information

IndiGene

Grant agreement ID: 810172

DOI 10.3030/810172

EC signature date 18 January 2019

Start date 1 February 2019

End date 31 July 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 6 272 613,00

EU contribution € 6 272 613,00

Coordinated by

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Data Management Plan for the Open Research Data Pilot

Publications

Peer reviewed articles (8)

Genomic variations and epigenomic landscape of the Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel

Author(s): Adrien Leger, Ian Brettell, Jack Monahan, Carl Barton, Nadeshda Wolf, Natalja Kusminski, Cathrin Herder, Narendar Aadepu, Clara Becker, Jakob Gierten, Omar T. Hammouda, Eva Hasel, Colin Lischik, Katharina Lust, Natalia Sokolova, Risa Suzuki, Tinatini Tavhelidse, Thomas Thumberger, Erika Tsingos, Philip Watson, Bettina Welz, Kiyoshi Naruse, Felix Loosli, Joachim Wittbrodt, Ewan Birney & Tomas Fitzg
Published in: Genome Biology, Issue 23, Article number: 58, 2022, ISSN 1474-760X
Publisher: Springer Nature
DOI: 10.1186/s13059-022-02602-4

Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development

Author(s): Lucie Zilova, Venera Weinhardt, Tinatini Tavhelidse, Christina Schlagheck, Thomas Thumberger, Joachim Wittbrodt
Published in: eLife, Issue 10, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.66998

Boosting targeted genome editing using the hei-tag

Author(s): Thomas ThumbergerTinatini Tavhelidse-SuckJose Arturo Gutierrez-TrianaAlex CorneanRebekka MedertBettina WelzMarc FreichelJoachim Wittbrodt
Published in: eLife, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.70558

The Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel

Author(s): Tomas Fitzgerald, Ian Brettell, Adrien Leger, Nadeshda Wolf, Natalja Kusminski, Jack Monahan, Carl Barton, Cathrin Herder, Narendar Aadepu, Jakob Gierten, Clara Becker, Omar T. Hammouda, Eva Hasel, Colin Lischik, Katharina Lust, Natalia Sokolova, Risa Suzuki, Erika Tsingos, Tinatini Tavhelidse, Thomas Thumberger, Philip Watson, Bettina Welz, Nadia Khouja, Kiyoshi Naruse, Ewan Birney, Joachim Wittb
Published in: Genome Biology, Issue 23, Article number: 59, 2022, ISSN 1474-760X
Publisher: Springer Nature
DOI: 10.1186/s13059-022-02623-z

Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions

Author(s): Jakob Gierten, Christian Pylatiuk, Omar T. Hammouda, Christian Schock, Johannes Stegmaier, Joachim Wittbrodt, Jochen Gehrig, Felix Loosli
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-58563-w

De novo PAM generation to reach initially inaccessible target sites for base editing

Author(s): Kaisa Pakari, Joachim Wittbrodt, Joachim Wittbrodt
Published in: Development, 2023, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.201115

CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart disease

Author(s): Lino Doering, Alex Cornean, Thomas Thumberger, Joergen Benjaminsen, Beate Wittbrodt, Tanja Kellner, Omar T. Hammouda, Matthias Gorenflo, Joachim Wittbrodt and Jakob Gierten
Published in: | Disease Models & Mechanisms, 2023, ISSN 1754-8403
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dmm.049811

Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction

Author(s): Alex Cornean, Jakob Gierten, Bettina Welz, Juan Luis Mateo, Thomas Thumberger, Joachim Wittbrodt
Published in: eLife, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.72124