Understanding Circumventing Antibiotic REsistance

Project Information

uCARE

Grant agreement ID: 819454

DOI 10.3030/819454

EC signature date 14 February 2019

Start date 1 March 2019

End date 31 August 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 986 004,00

EU contribution € 1 986 004,00

Coordinated by

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany

Publications

Peer reviewed articles (4)

SARS-CoV-2 infection remodels the host protein thermal stability landscape.

Author(s): Joel Selkrig; Megan L. Stanifer; André Mateus; Karin Mitosch; Inigo Barrio-Hernandez; Mandy Rettel; Heeyoung Kim; Carlos G P Voogdt; Philipp Walch; Philipp Walch; Carmon Kee; Nils Kurzawa; Nils Kurzawa; Frank Stein; Clement M. Potel; Anna Jarzab; Bernhard Kuster; Ralf Bartenschlager; Ralf Bartenschlager; Steeve Boulant; Steeve Boulant; Pedro Beltrao; Athanasios Typas; Mikhail M. Savitski
Published in: Molecular Systems Biology, Vol 17, Iss 2, Pp n/a-n/a (2021), Issue 1, 2021, ISSN 1744-4292
Publisher: Nature Publishing Group
DOI: 10.21203/rs.3.rs-105193/v1

Unravelling the collateral damage of antibiotics on gut bacteria

Author(s): Lisa Maier, Camille V. Goemans, Jakob Wirbel, Michael Kuhn, Claudia Eberl, Mihaela Pruteanu, Patrick Müller, Sarela Garcia-Santamarina, Elisabetta Cacace, Boyao Zhang, Cordula Gekeler, Tisya Banerjee, Exene Erin Anderson, Alessio Milanese, Ulrike Löber, Sofia K. Forslund, Kiran Raosaheb Patil, Michael Zimmermann, Bärbel Stecher, Georg Zeller, Peer Bork, Athanasios Typas
Published in: Nature, Issue 599/7883, 2021, Page(s) 120-124, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-021-03986-2

Bioactivity assessment of natural compounds using machine learning models trained on target similarity between drugs

Author(s): Vinita Periwal, Stefan Bassler, Sergej Andrejev, Natalia Gabrielli, Kaustubh Raosaheb Patil, Athanasios Typas, Kiran Raosaheb Pati
Published in: PLOS Computational Biology, 2023, ISSN 1553-7358
Publisher: Public Library of Science
DOI: 10.1371/journal.pcbi.1010029

Towards a mechanistic understanding of reciprocal drug–microbiome interactions

Author(s): Michael Zimmermann, Kiran Raosaheb Patil, Athanasios Typas, Lisa Maier
Published in: Molecular Systems Biology, Issue 17/3, 2021, ISSN 1744-4292
Publisher: Nature Publishing Group
DOI: 10.15252/msb.202010116

Other (1)

Emergence of community behaviors in the gut microbiota upon drug treatment

Author(s): Sarela Garcia-Santamarina, Michael Kuhn, Saravanan Devendran, Lisa Maier, Marja Driessen, André Mateus, Eleonora Mastrorilli, Ana Rita Brochado, Mikhail M. Savitski, Kiran R. Patil, Michael Zimmermann, Peer Bork, Athanasios Typas
Published in: bioRxiv, 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.06.13.544832

Intellectual Property Rights

Patent (2)

COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND/OR TREATMENT OF DYSBIOSIS AND ANTIBACTERIAL ANTIDOTES FOR MICROBIOME-PROTECTION

Application/Publication number: 19 216548
Date: 2019-12-16

COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND/OR TREATMENT OF DYSBIOSIS AND ANTIBACTERIAL ANTIDOTES FOR MICROBIOME-PROTECTION

Application/Publication number: 19 216548
Date: 2019-12-16