Skip to main content
Go to the home page of the European Commission (opens in new window)
English English
CORDIS - EU research results
CORDIS

Chromosome Replication Visualised by Cryo-EM

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Caught in the act: structural dynamics of replication origin activation and fork progression (opens in new window)

Author(s): Jacob S. Lewis, Alessandro Costa
Published in: Biochemical Society Transactions, Issue 48/3, 2020, Page(s) 1057-1066, ISSN 0300-5127
Publisher: Portland Press, Ltd.
DOI: 10.1042/bst20190998

Microtubule Nucleation Properties of Single Human γTuRCs Explained by Their Cryo-EM Structure (opens in new window)

Author(s): Tanja Consolati; Julia Locke; Johanna Roostalu; Zhuo Angel Chen; Julian Gannon; Jayant Asthana; Wei Ming Lim; Fabrizio Martino; Milos A. Cvetkovic; Juri Rappsilber; Alessandro Costa; Thomas Surrey
Published in: Developmental Cell, 2020, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2020.04.019

Mechanism of replication origin melting nucleated by CMG helicase assembly (opens in new window)

Author(s): Jacob S. Lewis, Marta H. Gross, Joana Sousa, Sarah S. Henrikus, Julia F. Greiwe, Andrea Nans, John F. X. Diffley & Alessandro Costa
Published in: Nature, 2022, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-04829-4

A Structure-Based Mechanism for DNA Entry into the Cohesin Ring (opens in new window)

Author(s): Torahiko L. Higashi, Patrik Eickhoff, Joana S. Sousa, Julia Locke, Andrea Nans, Helen R. Flynn, Ambrosius P. Snijders, George Papageorgiou, Nicola O’Reilly, Zhuo A. Chen, Francis J. O’Reilly, Juri Rappsilber, Alessandro Costa, Frank Uhlmann
Published in: Molecular Cell, Issue 79/6, 2020, Page(s) 917-933.e9, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2020.07.013

Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer (opens in new window)

Author(s): Valerie E Pye; David Rueda; Peter Cherepanov; Marcus Wilson; Mohamed Ghoneim; Ludovic Renault
Published in: Nature Communications, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1101/663336

Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM (opens in new window)

Author(s): Thomas C. R. Miller, Julia Locke, Julia F. Greiwe, John F. X. Diffley, Alessandro Costa
Published in: Nature, Issue 575/7784, 2019, Page(s) 704-710, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-019-1768-0

Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome (opens in new window)

Author(s): Patrik Eickhoff, Hazal B. Kose, Fabrizio Martino, Tatjana Petojevic, Ferdos Abid Ali, Julia Locke, Nele Tamberg, Andrea Nans, James M. Berger, Michael R. Botchan, Hasan Yardimci, Alessandro Costa
Published in: Cell Reports, Issue 28/10, 2019, Page(s) 2673-2688.e8, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2019.07.104

Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase (opens in new window)

Author(s): Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F. X. Diffley & Alessandro Costa
Published in: Nature Structural & Molecular Biology, 2022, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-021-00698-z

Searching for OpenAIRE data...

There was an error trying to search data from OpenAIRE

No results available

My booklet 0 0