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Chromosome Replication Visualised by Cryo-EM

Publikacje

Caught in the act: structural dynamics of replication origin activation and fork progression

Autorzy: Jacob S. Lewis, Alessandro Costa
Opublikowane w: Biochemical Society Transactions, Issue 48/3, 2020, Page(s) 1057-1066, ISSN 0300-5127
Wydawca: Portland Press, Ltd.
DOI: 10.1042/bst20190998

Microtubule Nucleation Properties of Single Human γTuRCs Explained by Their Cryo-EM Structure

Autorzy: Tanja Consolati; Julia Locke; Johanna Roostalu; Zhuo Angel Chen; Julian Gannon; Jayant Asthana; Wei Ming Lim; Fabrizio Martino; Milos A. Cvetkovic; Juri Rappsilber; Alessandro Costa; Thomas Surrey
Opublikowane w: Developmental Cell, 2020, ISSN 1534-5807
Wydawca: Cell Press
DOI: 10.1016/j.devcel.2020.04.019

Mechanism of replication origin melting nucleated by CMG helicase assembly

Autorzy: Jacob S. Lewis, Marta H. Gross, Joana Sousa, Sarah S. Henrikus, Julia F. Greiwe, Andrea Nans, John F. X. Diffley & Alessandro Costa
Opublikowane w: Nature, 2022, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-022-04829-4

A Structure-Based Mechanism for DNA Entry into the Cohesin Ring

Autorzy: Torahiko L. Higashi, Patrik Eickhoff, Joana S. Sousa, Julia Locke, Andrea Nans, Helen R. Flynn, Ambrosius P. Snijders, George Papageorgiou, Nicola O’Reilly, Zhuo A. Chen, Francis J. O’Reilly, Juri Rappsilber, Alessandro Costa, Frank Uhlmann
Opublikowane w: Molecular Cell, Issue 79/6, 2020, Page(s) 917-933.e9, ISSN 1097-2765
Wydawca: Cell Press
DOI: 10.1016/j.molcel.2020.07.013

Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer

Autorzy: Valerie E Pye; David Rueda; Peter Cherepanov; Marcus Wilson; Mohamed Ghoneim; Ludovic Renault
Opublikowane w: Wilson , M , Renault , L , Maskell , D P , Ghoneim , M , Pye , V E , Nans , A , Rueda , D S , Cherepanov , P & Costa , A 2019 , ' Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer ' , Nature Communications , vol. 10 , 4189 . https://doi.org/10.1038/s41467-019-12007-w, 2019, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1101/663336

Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM

Autorzy: Thomas C. R. Miller, Julia Locke, Julia F. Greiwe, John F. X. Diffley, Alessandro Costa
Opublikowane w: Nature, Issue 575/7784, 2019, Page(s) 704-710, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-019-1768-0

Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome

Autorzy: Patrik Eickhoff, Hazal B. Kose, Fabrizio Martino, Tatjana Petojevic, Ferdos Abid Ali, Julia Locke, Nele Tamberg, Andrea Nans, James M. Berger, Michael R. Botchan, Hasan Yardimci, Alessandro Costa
Opublikowane w: Cell Reports, Issue 28/10, 2019, Page(s) 2673-2688.e8, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2019.07.104

Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase

Autorzy: Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F. X. Diffley & Alessandro Costa
Opublikowane w: Nature Structural & Molecular Biology, 2022, ISSN 1545-9993
Wydawca: Nature Publishing Group
DOI: 10.1038/s41594-021-00698-z

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