The Quest of the Argonautes - from Myth to Reality

Project Information

ARGO

Grant agreement ID: 834279

DOI

10.3030/834279

Project closed

EC signature date 20 June 2019

Start date 1 July 2019

End date 30 June 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 177 157,50

EU contribution

€ 2 177 157,50

Coordinated by

WAGENINGEN UNIVERSITY
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (14)

Alternative functions of CRISPR–Cas systems in the evolutionary arms race

Author(s): Prarthana Mohanraju, Chinmoy Saha, Peter van Baarlen, Rogier Louwen, Raymond H. J. Staals, John van der Oost
Published in: Nature Reviews Microbiology, Issue 20, 2022, Page(s) 351-364, ISSN 1740-1526
Publisher: Nature Publishing Group
DOI: 10.1038/s41579-021-00663-z

Growth-uncoupled isoprenoid synthesis in Rhodobacter sphaeroides

Author(s): Enrico Orsi; Enrico Orsi; Ioannis Mougiakos; Wilbert Post; Jules Beekwilder; Marco Dompé; Gerrit Eggink; John van der Oost; Servé W. M. Kengen; Ruud A. Weusthuis
Published in: Biotechnology for biofuels, Issue 13/1, 2019, Page(s) 123, ISSN 1754-6834
Publisher: BioMed Central Ltd.
DOI: 10.1186/s13068-020-01765-1

Type III-B CRISPR-Cas cascade of proteolytic cleavages

Author(s): Jurre A. Steens, Jack P. K. Bravo, Carl Raymund P. Salazar, Caglar Yildiz, Afonso M. Amieiro, Stephan Köstlbacher, Stijn H. P. Prinsen, Ane S. Andres, Constantinos Patinios, Andreas Bardis, Arjan Barendregt, Richard A. Scheltema, Thijs J. G. Ettema, John van der Oost, David W. Taylor, Raymond H. J. Staals
Published in: Science, Issue 383, 2024, Page(s) 512-519, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.adk0378

Modulating CRISPR-Cas Genome Editing Using Guide-Complementary DNA Oligonucleotides

Author(s): Thomas Swartjes, Peng Shang, Dennis T.M. van den Berg, Tim Künne, Niels Geijsen, Stan J.J. Brouns, John van der Oost, Raymond H.J. Staals, Richard A. Notebaart
Published in: The CRISPR Journal, Issue 5, 2022, Page(s) 571-585, ISSN 2573-1599
Publisher: Mary Ann Liebert
DOI: 10.1089/crispr.2022.0011

Characterization of the AcrIIC1 anti‒CRISPR protein for Cas9‒based genome engineering in E. coli

Author(s): Despoina Trasanidou, Ana Potocnik, Patrick Barendse, Prarthana Mohanraju, Evgenios Bouzetos, Efthymios Karpouzis, Amber Desmet, Richard van Kranenburg, John van der Oost, Raymond H. J. Staals, Ioannis Mougiakos
Published in: Communications Biology, Issue 6, 2023, Page(s) 1042, ISSN 2399-3642
Publisher: Nature Springer
DOI: 10.1038/s42003-023-05418-5

The genome editing revolution

Author(s): van der Oost, John; Patinios, Constantinos
Published in: Trends in Biotechnology, Issue 41(3), 2022, Page(s) 396 - 409, ISSN 0167-7799
Publisher: Elsevier BV
DOI: 10.1016/j.tibtech.2022.12.022

Editor's cut: DNA cleavage by CRISPR RNA-guided nucleases Cas9 and Cas12a

Author(s): Thomas Swartjes; Raymond H.J. Staals; John van der Oost
Published in: Biochemical Society Transactions, Issue 02646021, 2020, Page(s) 207–219, ISSN 0264-6021
Publisher: Portland Press, Ltd.
DOI: 10.1042/bst20190563

Mechanistic and evolutionary insights into a type V-M CRISPR–Cas effector enzyme

Author(s): Satoshi N. Omura, Ryoya Nakagawa, Christian Südfeld, Ricardo Villegas Warren, Wen Y. Wu, Hisato Hirano, Charlie Laffeber, Tsukasa Kusakizako, Yoshiaki Kise, Joyce H. G. Lebbink, Yuzuru Itoh, John van der Oost, Osamu Nureki
Published in: Nature Structural & Molecular Biology, Issue 30, 2023, Page(s) 1172-1182, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-023-01042-3

A hyperthermoactive-Cas9 editing tool reveals the role of a unique arsenite methyltransferase in the arsenic resistance system of Thermus thermophilus HB27

Author(s): Giovanni Gallo; Ioannis Mougiakos; Bianco M; Carbonaro M; Andrea Carpentieri; Illiano A; Piero Pucci; Simonetta Bartolucci; van der Oost J; Gabriella Fiorentino
Published in: mBio, Issue 21612129, 2021, Page(s) e02813-21, ISSN 2161-2129
Publisher: American Society for Microbiology
DOI: 10.1101/2021.07.12.452139

(R)evolution-on-a-chip.

Author(s): Bouzetos, Evgenios; Ganar, Ketan Ashok; Mastrobattista, Enrico; Deshpande, Siddharth; van der Oost, John; Afd Pharmaceutics; Pharmaceutics
Published in: Trends in Biotechnology, Issue 40/1, 2022, Page(s) 60-67, ISSN 0167-7799
Publisher: Elsevier BV
DOI: 10.1016/j.tibtech.2021.04.009

Efficient Cas9-based genome editing of Rhodobacter sphaeroides for metabolic engineering

Author(s): Ioannis Mougiakos; Enrico Orsi; Mohammad Rifqi Ghiffary; Mohammad Rifqi Ghiffary; Wilbert Post; Alberto De Maria; Alberto De Maria; Belén Adiego-Pérez; Servé W. M. Kengen; Ruud A. Weusthuis; John van der Oost
Published in: Microbial Cell Factories, Issue 18/1, 2019, ISSN 2076-2607
Publisher: Springer Nature
DOI: 10.1186/s12934-019-1255-1

Cryo-EM structure of the transposon-associated TnpB enzyme

Author(s): Ryoya Nakagawa, Hisato Hirano, Satoshi N. Omura, Suchita Nety, Soumya Kannan, Han Altae-Tran, Xiao Yao, Yuriko Sakaguchi, Takayuki Ohira, Wen Y. Wu, Hiroshi Nakayama, Yutaro Shuto, Tatsuki Tanaka, Fumiya K. Sano, Tsukasa Kusakizako, Yoshiaki Kise, Yuzuru Itoh, Naoshi Dohmae, John van der Oost, Tsutomu Suzuki, Feng Zhang, Osamu Nureki
Published in: Nature, Issue 616, 2023, Page(s) 390-397, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-023-05933-9

The miniature CRISPR-Cas12m effector binds DNA to block transcription

Author(s): Wen Y. Wu, Prarthana Mohanraju, Chunyu Liao, Belén Adiego-Pérez, Sjoerd C.A. Creutzburg, Kira S. Makarova, Karlijn Keessen, Timon A. Lindeboom, Tahseen S. Khan, Stijn Prinsen, Rob Joosten, Winston X. Yan, Anzhela Migur, Charlie Laffeber, David A. Scott, Joyce H.G. Lebbink, Eugene V. Koonin, Chase L. Beisel, John van der Oost
Published in: Molecular Cell, Issue 82, 2024, Page(s) 4487-4502.e7, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.11.003

Streamlined CRISPR genome engineering in wild-type bacteria using SIBR-Cas.

Author(s): Constantinos Patinios; Sjoerd C.A. Creutzburg; Adini Q Arifah; Belén Adiego-Pérez; Evans A Gyimah; Colin J. Ingham; Servé W. M. Kengen; John van der Oost; Raymond H.J. Staals
Published in: Nucleic acids research, Issue 49/19, 2021, Page(s) 11392-11404, ISSN 1362-4962
Publisher: Oxford Academic
DOI: 10.1093/nar/gkab893

Non-peer reviewed articles (2)

First structural insights into CRISPR-Cas-guided DNA transposition

Author(s): John van der Oost, Ioannis Mougiakos
Published in: Cell Research, Issue 30, 2023, Page(s) 193-194, ISSN 1001-0602
Publisher: Kexue Chubaneshe/Science Press
DOI: 10.1038/s41422-020-0284-y

Compact but mighty: Biology and applications of type III-E CRISPR-Cas systems

Author(s): Jurre A. Steens, John van der Oost, Raymond H.J. Staals
Published in: Molecular Cell, Issue 82, 2024, Page(s) 4405-4406, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.11.007