Nanomachines as new antimicrobial agents
Antimicrobial resistance (AMR) is a major health concern worldwide, necessitating the development of novel antibiotics. Molecular nanomachines (MNMs) are synthetic organic molecules that can penetrate lipid bilayers using a rotational movement, and they have emerged as promising antimicrobial alternatives. The EU-funded REBELLION project proposes to synthesise and screen MNMs that respond to light. Scientists will evaluate the candidate molecules for their efficacy against a range of microbial targets and for their safety in mammalian cells. Apart from greater selectivity, these innovative antimicrobials demonstrate a lower potential for the development of AMR.
Fields of science
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- engineering and technologynanotechnology
- social sciencespolitical sciencespolitical transitionsrevolutions
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibiotics
- medical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceantibiotic resistance
Funding SchemeMSCA-IF-GF - Global Fellowships
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
01463 Pepperell Ma
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