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Light-REsponsive Nanomachines for Targeted Eradication of BactErial Pathogens in LocaLised InfectIONs

Project description

Nanomachines as new antimicrobial agents

Antimicrobial resistance (AMR) is a major health concern worldwide, necessitating the development of novel antibiotics. Molecular nanomachines (MNMs) are synthetic organic molecules that can penetrate lipid bilayers using a rotational movement, and they have emerged as promising antimicrobial alternatives. The EU-funded REBELLION project proposes to synthesise and screen MNMs that respond to light. Scientists will evaluate the candidate molecules for their efficacy against a range of microbial targets and for their safety in mammalian cells. Apart from greater selectivity, these innovative antimicrobials demonstrate a lower potential for the development of AMR.

Coordinator

FUNDACIO INSTITUT D'INVESTIGACIO SANITARIA ILLES BALEARS
Net EU contribution
€ 245 732,16
Address
Carretera De Valldemossa, 79
07120 Palma
Spain

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Region
Este Illes Balears Mallorca
Activity type
Research Organisations
Other funding
€ 245 732,16

Partners (1)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

GAMA THERAPEUTICS LLC
United States
Net EU contribution
€ 0,00
Address
20 Mill Street Unit 201
01463 Pepperell Ma

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00