Personalized immunotherapy in sepsis: a precision medicine based approach

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First study approval package: final version of study protocol as approved by first regulator / ethics committee, registration in a WHO- or ICMJE- approved registry, approval for enrolment of first subject in at least one clinical centre

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Modes of action and diagnostic value of miRNAs in sepsis

Autori: Nikolaos Antonakos, Charly Gilbert, Charlotte Théroude, Irene T Schrijver, Thierry Roger
Pubblicato in: Frontiers in Immunology, 2022, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2022.951798

ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol

Autori: Antigone Kotsaki; Peter Pickkers; Michael Bauer; Thierry Calandra; Mihaela Lupse; W Joost Wiersinga; Sylvain Meylan; Frank Bloos; Tom van der Poll; Marleen A Slim; Niels van Mourik; Marcella C A Müller; Lonneke van Vught; Alexander P J Vlaar; Aline de Nooijer; Lieke Bakkerus; Sebastian Weis; Nikolaos Antonakos; Mihai G Netea; Evangelos J Giamarellos-Bourboulis
Pubblicato in: BMJ Open, 2022, ISSN 2044-6055
Editore: BMJ Publishing Group
DOI: 10.1136/bmjopen-2022-067251

Editorial: Macrophage Plasticity in Sterile and Pathogen-Induced Inflammation

Autori: Kourtzelis, Ioannis; Hewitson, James; Roger, Thierry
Pubblicato in: Frontiers in Immunology, Numero 4, 2021, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2021.823023

An integrative model of cardiometabolic traits identifies two types of metabolic syndrome

Autori: Amit Frishberg, Inge van den Munckhof, Rob ter Horst, Kiki Schraa, Leo AB Joosten, Joost HW Rutten, Adrian C Iancu, Ioana M Dregoesc, Bogdan A Tigu, Mihai G Netea, Niels P Riksen, Irit Gat-Viks
Pubblicato in: eLife, Numero 10, 2021, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.61710

Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis

Autori: George Dimopoulos, Quirijn de Mast, Nikolaos Markou, Maria Theodorakopoulou, Apostolos Komnos, Maria Mouktaroudi, Mihai G. Netea, Themistoklis Spyridopoulos, Rebecca J. Verheggen, Jacobien Hoogerwerf, Alexandra Lachana, Frank L. van de Veerdonk, Evangelos J. Giamarellos-Bourboulis
Pubblicato in: Cell Host & Microbe, Numero 28/1, 2020, Pagina/e 117-123.e1, ISSN 1931-3128
Editore: Cell Press
DOI: 10.1016/j.chom.2020.05.007

Personalised immunotherapy in sepsis: a scoping review protocol

Autori: Marleen A Slim; Niels van Mourik; Joanna C Dionne; Simon J W Oczkowski; M G Netea; Peter Pickkers; Evangelos J Giamarellos-Bourboulis; Marcella C A Müller; Tom van der Poll; W Joost Wiersinga; Alexander P J Vlaar; Lonneke A van Vught
Pubblicato in: BMJ Open, 2022, ISSN 2044-6055
Editore: BMJ Publishing Group
DOI: 10.1136/bmjopen-2021-060411

Myeloid-Derived Suppressor-like Cells as a Prognostic Marker in Critically Ill Patients: Insights from Experimental Endotoxemia and Intensive Care Patients

Autori: Irene T. Schrijver, Jacobus Herderschee, Charlotte Théroude, Antonios Kritikos, Guus Leijte, Didier Le Roy, Maelick Brochut, Jean-Daniel Chiche, Matthieu Perreau, Giuseppe Pantaleo, Benoit Guery, Matthijs Kox, Peter Pickkers, Thierry Calandra, Thierry Roger
Pubblicato in: Cells, 2024, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells13040314

Sepsis: deriving biological meaning and clinical applications from high-dimensional data.

Autori: Alex R. Schuurman; Tom D Y Reijnders; Robert F. J. Kullberg; Joe M. Butler; Tom van der Poll; W. Joost Wiersinga
Pubblicato in: Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-15 (2021), 2021, ISSN 2197-425X
Editore: Springer
DOI: 10.1186/s40635-021-00383-x

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

Autori: Evangelos J. Giamarellos-Bourboulis, Mihai G. Netea, Nikoletta Rovina, Karolina Akinosoglou, Anastasia Antoniadou, Nikolaos Antonakos, Georgia Damoraki, Theologia Gkavogianni, Maria-Evangelia Adami, Paraskevi Katsaounou, Maria Ntaganou, Magdalini Kyriakopoulou, George Dimopoulos, Ioannis Koutsodimitropoulos, Dimitrios Velissaris, Panagiotis Koufargyris, Athanassios Karageorgos, Konstantina Katrini
Pubblicato in: Cell Host & Microbe, Numero 27/6, 2020, Pagina/e 992-1000.e3, ISSN 1931-3128
Editore: Cell Press
DOI: 10.1016/j.chom.2020.04.009

Editorial: Beneficial and pathological roles of myeloid cells during COVID-19.

Autori: Lokesh Sharma; Shaon Sengupta; Thierry Roger
Pubblicato in: Frontiers in immunology, vol. 14, pp. 1194826, Numero 4, 2023, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2023.1194826

Editorial: The Immunology of Sepsis-Understanding Host Susceptibility, Pathogenesis of Disease, and Avenues for Future Treatment.

Autori: Luregn J. Schlapbach; Luregn J. Schlapbach; Johannes Trück; Thierry Roger
Pubblicato in: Frontiers in Immunology, Numero 6, 2020, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2020.01263

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