Microrobotic Gamete/Zygote IntraFallopian Transfer

Informazioni relative al progetto

Micro-GIFT

ID dell’accordo di sovvenzione: 853609

DOI

10.3030/853609

Data della firma CE 28 Febbraio 2020

Data di avvio 1 Aprile 2020

Data di completamento 30 Settembre 2026

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 499 967,00

Contributo UE

€ 1 499 967,00

Coordinato da

ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN NANOCIENCIAS CIC NANOGUNE
Spain

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (34)

Electronically integrated microcatheters based on self-assembling polymer films

Autori: Boris Rivkin, Christian Becker, Balram Singh, Azaam Aziz, Farzin Akbar, Aleksandr Egunov, Dmitriy D. Karnaushenko, Ronald Naumann, Rudolf Schäfer, Mariana Medina-Sánchez, Daniil Karnaushenko, Oliver G. Schmidt
Pubblicato in: Science Advances, Numero 7, 2024, ISSN 2375-2548
Editore: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciadv.abl5408

Sperm‐Driven Micromotors Moving in Oviduct Fluid and Viscoelastic Media

Autori: Friedrich Striggow, Mariana Medina‐Sánchez, Günter K. Auernhammer, Veronika Magdanz, Benjamin M. Friedrich, Oliver G. Schmidt
Pubblicato in: Small, Numero 16/24, 2020, Pagina/e 2000213, ISSN 1613-6810
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202000213

P-260 In Vitro Fertilization (IVF) using magnetotactic sperm cells and their prospects for assisted in vivo reproduction

Autori: C Ribeiro, F Striggow, F Hebenstreit, R Nauber, J Schoen, M Medina-Sanchez
Pubblicato in: Human Reproduction, Numero 39, 2024, ISSN 0268-1161
Editore: Oxford University Press
DOI: 10.1093/humrep/deae108.630

Smart Surface Engineering in Microcarriers: Toward Applications in Cancer Therapy

Autori: Fatemeh Rajabasadi, Silvia Moreno, Mercedes Gonzalez Rico, Pedro Viñola, Kristin Fichna, Franziska Hebenstreit, Susanne Boye, Andreas Janke, Dietmar Appelhans, Mariana Medina‐Sánchez
Pubblicato in: Macromolecular Materials and Engineering, 2025, ISSN 1438-7492
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/mame.202500058

Medical Microrobots in Reproductive Medicine: From the bench to the clinic

Autori: Richard Nauber, Sandhya Rani Goudu, M. Goeckenjan, M. Bornhäuser, Carla Ribeiro, M. Medina-Sánchez
Pubblicato in: Nature Communications, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-36215-7

Real‐Time IR Tracking of Single Reflective Micromotors through Scattering Tissues

Autori: Azaam Aziz, Mariana Medina‐Sánchez, Nektarios Koukourakis, Jiawei Wang, Robert Kuschmierz, Hannes Radner, Jürgen W. Czarske, Oliver G. Schmidt
Pubblicato in: Advanced Functional Materials, Numero 29/51, 2019, Pagina/e 1905272, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201905272

Technology Roadmap of Micro/Nanorobots

Autori: Xiaohui Ju, Chuanrui Chen, Cagatay M. Oral, Semih Sevim, Ramin Golestanian, Mengmeng Sun, Negin Bouzari, Xiankun Lin, Mario Urso, Jong Seok Nam, Yujang Cho, Xia Peng, Fabian C. Landers, Shihao Yang, Azin Adibi, Nahid Taz, Raphael Wittkowski, Daniel Ahmed, Wei Wang, Veronika Magdanz, Mariana Medina-Sánchez, Maria Guix, Naimat Bari, Bahareh Behkam, Raymond Kapral, Yaxin Huang, Jinyao Tang, Ben Wang
Pubblicato in: ACS Nano, Numero 19, 2025, Pagina/e 24174-24334, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.5c03911

Self-assembled sensor-in-a-tube as a versatile tool for label-free EIS viability investigation of cervical cancer cells

Autori: Eashika Ghosh, Aleksandr I. Egunov, Daniil Karnaushenko, Mariana Medina-Sánchez, Oliver G. Schmidt
Pubblicato in: Frequenz, Numero 76, 2023, Pagina/e 729-740, ISSN 0016-1136
Editore: Fachverlag Schiele and Schoen GmbH
DOI: 10.1515/freq-2022-0090

Electronically integrated micro-catheters based on self-assembling polymer films

Autori: Boris Rivkin, Christian Becker, Balram Singh, Azaam Aziz, Farzin Akbar, Aleksandr Egunov, Dmitriy D. Karnaushenko, Ronald Naumann, Rudolf Schäfer, Mariana Medina-Sánchez, Daniil Karnaushenko, Oliver G. Schmidt
Pubblicato in: Science Advances, 2021, ISSN 2375-2548
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abl540

Microrobots in gynaecological care and reproductive medicine

Autori: Zhi Chen, Mariana Medina Sánchez
Pubblicato in: Nature Reviews Electrical Engineering, Numero 1, 2024, Pagina/e 759-761, ISSN 2948-1201
Editore: Springer Science and Business Media LLC
DOI: 10.1038/s44287-024-00102-0

Special Issue on Computational Ultrasound Imaging and Applications

Autori: Richard Nauber; Lars Büttner; Jürgen Czarske
Pubblicato in: Applied Sciences, Vol 14, Iss 3, p 964 (2024), Numero 2, 2023, ISSN 2078-2489
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/app14030964

Remotely Controlled Electrochemical Degradation of Metallic Implants

Autori: Boris Rivkin, Farzin Akbar, Martin Otto, Lukas Beyer, Birgit Paul, Konrad Kosiba, Tobias Gustmann, Julia Hufenbach, Mariana Medina‐Sánchez
Pubblicato in: Small, Numero 20, 2024, ISSN 1613-6810
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202307742

Responsive Magnetic Nanocomposites for Intelligent Shape-Morphing Microrobots

Autori: Yuan Liu; Gungun Lin; Mariana Medina-Sánchez; Maria Guix; Denys Makarov; Dayong Jin
Pubblicato in: ACS Nano 17(2023), 8899, Numero 4, 2023, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.3c01609

3D nanofabricated soft microrobots with super-compliant picoforce springs as onboard sensors and actuators

Autori: Haifeng Xu, Song Wu, Yuan Liu, Xiaopu Wang, Artem K. Efremov, Lei Wang, John S. McCaskill, Mariana Medina-Sánchez, Oliver G. Schmidt
Pubblicato in: Nature Nanotechnology, Numero 19, 2024, Pagina/e 494-503, ISSN 1748-3387
Editore: Nature Publishing Group
DOI: 10.1038/s41565-023-01567-0

Human spermbots for patient-representative 3D ovarian cancer cell treatment

Autori: Haifeng Xu, Mariana Medina-Sánchez, Wunan Zhang, Melanie P. H. Seaton, Daniel R. Brison, Richard J. Edmondson, Stephen S. Taylor, Louisa Nelson, Kang Zeng, Steven Bagley, Carla Ribeiro, Lina P. Restrepo, Elkin Lucena, Christine K. Schmidt, Oliver G. Schmidt
Pubblicato in: Nanoscale, Numero 12/39, 2020, Pagina/e 20467-20481, ISSN 2040-3364
Editore: Royal Society of Chemistry
DOI: 10.1039/d0nr04488a

Magnetic Micromotors for Multiple Motile Sperm Cells Capture, Transport, and Enzymatic Release

Autori: Haifeng Xu; Mariana Medina-Sánchez; Oliver G. Schmidt; Oliver G. Schmidt
Pubblicato in: Angewandte Chemie (International Ed. in English), Numero 1, 2020, ISSN 1521-3773
Editore: Wiley
DOI: 10.1002/anie.202005657

Dual Ultrasound and Photoacoustic Tracking of Magnetically Driven Micromotors: From In Vitro to In Vivo

Autori: Azaam Aziz, Joost Holthof, Sandra Meyer, Oliver G. Schmidt, Mariana Medina‐Sánchez
Pubblicato in: Advanced Healthcare Materials, Numero 10, 2023, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202101077

3D and 4D Lithography of Untethered Microrobots

Autori: Fatemeh Rajabasadi, Lukas Schwarz, Mariana Medina-Sánchez, O.G. Schmidt
Pubblicato in: Progress in Material Science, 2021, ISSN 1873-2208
Editore: Elsevier Ltd
DOI: 10.1016/j.pmatsci.2021.100808

Medical Imaging of Microrobots: Toward In Vivo Applications

Autori: Azaam Aziz, Stefano Pane, Veronica Iacovacci, Nektarios Koukourakis, Jürgen Czarske, Arianna Menciassi, Mariana Medina-Sánchez, Oliver G. Schmidt
Pubblicato in: ACS Nano, Numero 14/9, 2020, Pagina/e 10865-10893, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.0c05530

In vivo imaging of swimming micromotors using hybrid high-frequency ultrasound and photoacoustic imaging

Autori: Azaam Aziz, J. Holthof, S. Meyer, O.G. Schmidt, M. Medina-Sánchez
Pubblicato in: Advanced Healthcare Materials, 2021, ISSN 2192-2659
Editore: World Scientific
DOI: 10.1101/2020.06.15.148791

A Rotating Spiral Micromotor for Noninvasive Zygote Transfer

Autori: Lukas Schwarz, Dmitriy D. Karnaushenko, Franziska Hebenstreit, Ronald Naumann, Oliver G. Schmidt, Mariana Medina‐Sánchez
Pubblicato in: Advanced Science, Numero 7/18, 2020, Pagina/e 2000843, ISSN 2198-3844
Editore: Wiley
DOI: 10.1002/advs.202000843

Multimodal Imaging, Drug Delivery, and On‐Board Triggered Degradation in Soft Capsule Rolling Microrobots

Autori: David Castellanos‐Robles, Raphaël C. L.‐M. Doineau, Azaam Aziz, Richard Nauber, Song Wu, Silvia Moreno, Konstantina Mitropoulou, Franziska Hebenstreit, Mariana Medina‐Sánchez
Pubblicato in: Advanced Intelligent Systems, Numero 6, 2024, ISSN 2640-4567
Editore: Wiley
DOI: 10.1002/aisy.202400230

Nano-biosupercapacitors enable autarkic sensor operation in blood

Autori: Yeji Lee, Vineeth Kumar Bandari, Zhe Li, Mariana Medina-Sánchez, Manfred F. Maitz, Daniil Karnaushenko, Mikhail V. Tsurkan, Dmitriy D. Karnaushenko, Oliver G. Schmidt
Pubblicato in: Nature Communications, Numero 12, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-24863-6

Small Scale Propulsion: How Systematic Studies of Low Reynolds Number Physics Can Bring Micro/Nanomachines to New Horizons

Autori: Wrede, Paul; Medina-Sánchez, Mariana; Fomin, Vladimir M.
Pubblicato in: Journal of Nanotechnology and Nanomaterials, Numero 3, 2022, ISSN 2692-630X
Editore: IOP Publishing
DOI: 10.33696/nanotechnol.3.028

Micromotor-mediated sperm constrictions for improved swimming performance

Autori: F. Striggow, L. Nadporozhskaia, B. M. Friedrich, O. Schmidt, M. Medina-Sánchez
Pubblicato in: The European Physical Journal E, 2021, ISSN 1292-8941
Editore: Springer Verlag
DOI: 10.1140/epje/s10189-021-00050-9

Advanced materials for micro/nanorobotics

Autori: Jeonghyo Kim, Paula Mayorga-Burrezo, Su-Jin Song, Carmen C. Mayorga-Martinez, Mariana Medina-Sánchez, Salvador Pané, Martin Pumera
Pubblicato in: Chemical Society Reviews, Numero 53, 2024, Pagina/e 9190-9253, ISSN 0306-0012
Editore: Royal Society of Chemistry
DOI: 10.1039/d3cs00777d

Advancements in Machine Learning for Microrobotics in Biomedicine

Autori: Amar Salehi, Soleiman Hosseinpour, Nasrollah Tabatabaei, Mahmoud Soltani Firouz, Niloufar Zadebana, Richard Nauber, Mariana Medina‐Sánchez
Pubblicato in: Advanced Intelligent Systems, 2024, ISSN 2640-4567
Editore: Wiley
DOI: 10.1002/aisy.202400458

Multifunctional 4D‐Printed Sperm‐Hybrid Microcarriers for Assisted Reproduction

Autori: Fatemeh Rajabasadi, Silvia Moreno, Kristin Fichna, Azaam Aziz, Dietmar Appelhans, Oliver G. Schmidt, Mariana Medina-Sánchez
Pubblicato in: Advanced Materials, 2022, ISSN 1521-4095
Editore: Wiley
DOI: 10.1002/adma.202204257

Shape‐Controlled Flexible Microelectronics Facilitated by Integrated Sensors and Conductive Polymer Actuators

Autori: Boris Rivkin, Christian Becker, Farzin Akbar, Rachappa Ravishankar, Dmitriy D. Karnaushenko, Ronald Naumann, Alaleh Mirhajivarzaneh, Mariana Medina-Sánchez, Daniil Karnaushenko, Oliver G. Schmidt
Pubblicato in: Advanced Intelligent Systems, Numero 3/6, 2021, Pagina/e 2000238, ISSN 2640-4567
Editore: Wiley
DOI: 10.1002/aisy.202000238

Nanomaterial-decorated micromotors for enhanced photoacoustic imaging

Autori: Azaam Aziz, Richard Nauber, Ana Iglesias-Sánchez, L-M. Marzán, O.G. Schmidt, M. Medina-Sánchez.
Pubblicato in: Micro-BioRobotics, 2023, ISSN 2194-6426
Editore: Springer
DOI: 10.1007/s12213-023-00156-7

Engineering microrobots for targeted cancer therapies from a medical perspective

Autori: Christine K. Schmidt, Mariana Medina-Sánchez, Richard J. Edmondson, Oliver G. Schmidt
Pubblicato in: Nature Communications, Numero 11, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-19322-7

Sperm Micromotors for Cargo Delivery through Flowing Blood

Autori: Haifeng Xu, Mariana Medina-Sánchez, Manfred F. Maitz, Carsten Werner, Oliver G. Schmidt
Pubblicato in: ACS Nano, Numero 14/3, 2020, Pagina/e 2982-2993, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.9b07851

Portable microfluidic impedance biosensor for SARS-CoV-2 detection

Autori: Soroush Laleh, Bergoi Ibarlucea, Marlena Stadtmüller, Gianaurelio Cuniberti, Mariana Medina-Sánchez
Pubblicato in: Biosensors and Bioelectronics, Numero 236, 2023, Pagina/e 115362, ISSN 0956-5663
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.bios.2023.115362

IRONSperm: Sperm-templated soft magnetic microrobots.

Autori: Veronika Magdanz; Islam S. M. Khalil; Juliane Simmchen; Guilherme Phillips Furtado; Sumit Mohanty; Johannes Gebauer; Haifeng Xu; Anke Klingner; Azaam Aziz; Mariana Medina-Sánchez; Oliver G. Schmidt; Oliver G. Schmidt; Oliver G. Schmidt; Sarthak Misra; Sarthak Misra
Pubblicato in: Science Advances, Numero 1, 2020, ISSN 2375-2548
Editore: American Academy of Arts and Sciences
DOI: 10.34657/3695

Conference proceedings (5)

Optimization of Smart Microactuators Utilizing 2D and 3D Lithography

Autori: Sumaiya Tahera Rahman, David Castellanos Robles, Fatemeh Rajabasadi, Mariana Medina-Sánchez
Pubblicato in: 2024 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS), 2024, Pagina/e 1-6
Editore: IEEE
DOI: 10.1109/marss61851.2024.10612708

Photoacoustics-Guided Real-Time Closed-Loop Control of Magnetic Microrobots Through Deep Learning

Autori: Richard Nauber, Johanna Hoppe, David Castellanos Robles, Mariana Medina-Sánchez
Pubblicato in: 2024 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS), 2024, Pagina/e 1-5
Editore: IEEE
DOI: 10.1109/marss61851.2024.10612756

Tracking of Magnetic Micromotors in Confined Channels Through Scattering Tissue

Autori: Azaam Aziz; Dmitriy Karnaushenko; Nektarios Koukourakis; Jurgen W. Czarske; Oliver G. Schmidt; Mariana Medina-Sanchez
Pubblicato in: Crossref, Numero 1, 2022
Editore: NanoMed
DOI: 10.1109/nanomed54179.2021.9766491

Study of the influence of loss function weights with YOLOv8 and YOLOv9 on the tracking accuracy of medical microrobots

Autori: Johanna Hoppe, Richard Nauber, David Castellanos Robles, Juergen Czarske
Pubblicato in: 024 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS), bioRxiv, 2025
Editore: bioRxiv

Microrobot’s Performance in Cell-Lining Surfaces and Ex-vivo Tissue

Autori: Carla Ribeiro, Richard Nauber, Azaam Aziz, David Castellanos Robles, Franziska Hebenstreit, Mariana Medina-Sánchez
Pubblicato in: 2025
Editore: International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS)
DOI: 10.21203/rs.3.rs-5415311/v1

Book chapters (2)

Geometry matters: Gamete transport using magnetic microrobots

Autori: David Castellanos Robles, Farzin Akbar, Mariana Medina-Sánchez
Pubblicato in: Encyclopedia of Condensed Matter Physics, 2024, Pagina/e 540-551
Editore: Elsevier
DOI: 10.1016/b978-0-323-90800-9.00231-6

Sperm-micromotors for assisted reproduction and drug delivery

Autori: Friedrich Striggow, Farzin Akbar, Azaam Aziz, Mariana Medina-Sánchez
Pubblicato in: Recent Progress in Medical Miniature Robots, 2024, Pagina/e 239-264
Editore: Elsevier
DOI: 10.1016/b978-0-443-13385-5.00003-9

Thesis and dissertations (1)

Magnetic Micromotors in Assisted Reproductive Technology

Autori: Lukas Schwarz
Pubblicato in: 2020
Editore: TU Chemnitz

Other (1)

Three-dimensional microtomography

Autori: O. G. Schmidt, M. Medina-Sánchez, S. M. Weiz
Pubblicato in: 2020
Editore: US Patent App. 16/462,743, 2020