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Investigating the role of the inner retina in age-related macular degeneration (AMD)

Publications

Vascular Expression of Permeability-Resistant Occludin Mutant Preserves Visual Function in Diabetes.

Auteurs: Andreia Goncalves, Alyssa Dreffs, Cheng-Mao Lin, Sarah Sheskey, Natalie Hudson, Jason Keil, Matthew Campbell, David A Antonetti
Publié dans: Diabetes, 2021, ISSN 0012-1797
Éditeur: American Diabetes Association
DOI: 10.2337/db20-1220

Fibrotic Changes to Schlemm's Canal Endothelial Cells in Glaucoma.

Auteurs: Kelly RA, Perkumas KM, Campbell M, Farrar GJ, Stamer WD, Humphries P, O'Callaghan J, O'Brien CJ.
Publié dans: Int J Mol Sci, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22179446

S100B, GFAP, UCH-L1 and NSE as predictors of abnormalities on CT imaging following mild traumatic brain injury: a systematic review and meta-analysis of diagnostic test accuracy.

Auteurs: Amoo M, Henry J, O'Halloran PJ, Brennan P, Husien MB, Campbell M, Caird J, Javadpour M, Curley GF.
Publié dans: Neurosurgical Review, 2021, ISSN 1437-2320
Éditeur: Springer
DOI: 10.1007/s10143-021-01678-z

Microglia-Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model.

Auteurs: Boyce M, Xin Y, Chowdhury O, Shang P, Liu H, Koontz V, Strizhakova A, Nemani M, Hose S, Zigler JS Jr, Campbell M, Sinha D, Handa JT, Kaarniranta K, Qian J, Ghosh S.
Publié dans: Cells, 2022, ISSN 2073-4409
Éditeur: MDPI

The blood-retina barrier in health and disease

Auteurs: Fionn O'Leary and Matthew Campbell
Publié dans: FEBS Journal, Numéro Dec 18, 2021, ISSN 1742-464X
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/febs.16330

Decreased CSF1R Signaling and the Accumulation of Reticular Pseudo-Drusen?

Auteurs: Deirdre A Harford, Conor Delaney, Jeffrey O'Callaghan, Natalie Hudson, Ruairi Connolly, Sarah Doyle, Michael Farrell, Colin P Doherty, Mark Cahill, Matthew Campbell
Publié dans: OSLI Retina, Numéro Dec;52(12):666-671., 2021, ISSN 2325-8160
Éditeur: Slack Incorporated
DOI: 10.3928/23258160-20211101-01

Claudin-5: A Pharmacological Target to Modify the Permeability of the Blood-Brain Barrier.

Auteurs: Hashimoto Y, Campbell M, Tachibana K, Okada Y, Kondoh M.
Publié dans: Biol Pharm Bull, 2021, ISSN 1347-5215
Éditeur: J-Stage
DOI: 10.1248/bpb.b21-00408

Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue.

Auteurs: Dion-Albert L, Cadoret A, Doney E, Kaufmann FN, Dudek KA, Daigle B, Parise LF, Cathomas F, Samba N, Hudson N, Lebel M; Signature Consortium; Campbell M, Turecki G, Mechawar N, Menard C.
Publié dans: Nature Communications, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-021-27604-x

Tight Junctions of the Neurovascular Unit

Auteurs: Natalie Hudson, Matthew Campbell
Publié dans: Front Mol Neurosci, Numéro Nov 19;14:752781, 2021, ISSN 1662-5099
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fnmol.2021.752781

Methamphetamine enhances caveolar transport of therapeutic agents across the rodent blood-brain barrier

Auteurs: Chang JH, Greene C, Frudd K, Araujo Dos Santos L, Futter C, Nichols BJ, Campbell M, Turowski P.
Publié dans: Cell Reports Medicine, 2022, ISSN 2666-3791
Éditeur: Elsevier
DOI: 10.1016/j.xcrm.2021.100497

Vascular Expression of Permeability-Resistant Occludin Mutant Preserves Visual Function in Diabetes

Auteurs: Andreia Goncalves; Alyssa Dreffs; Cheng-mao Lin; Sarah Sheskey; Natalie Hudson; Jason M. Keil; Matthew Campbell; David A. Antonetti
Publié dans: Diabetes, Numéro 1, 2022, ISSN 1939-327X
Éditeur: American Diabetes Association
DOI: 10.2337/figshare.14364086

Minocycline suppresses disease-associated microglia (DAM) in a model of photoreceptor cell degeneration.

Auteurs: Ozaki E, Delaney C, Campbell M, Doyle SL.
Publié dans: Experimental Eye Research, 2022, ISSN 0014-4835
Éditeur: Academic Press
DOI: 10.1016/j.exer.2022.108953

Permeability of the Blood-Brain Barrier after Traumatic Brain Injury: Radiological Considerations.

Auteurs: Amoo M, O'Halloran PJ, Henry J, Ben Husien M, Brennan P, Campbell M, Caird J, Curley GF.
Publié dans: Journal of Neurotrauma, 2021, ISSN 1557-9042
Éditeur: Mary Ann Liebert
DOI: 10.1089/neu.2020.7545

Microvascular stabilization via blood-brain barrier regulation prevents seizure activity

Auteurs: Greene C, Hanley N, Reschke CR, Reddy A, Mäe MA, Connolly R, Behan C, O'Keeffe E, Bolger I, Hudson N, Delaney C, Farrell MA, O'Brien DF, Cryan J, Brett FM, Beausang A, Betsholtz C, Henshall DC, Doherty CP, Campbell M.
Publié dans: Nature Communications, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-022-29657-y

Concussion susceptibility is mediated by spreading depolarization-induced neurovascular dysfunction.

Auteurs: Parker E, Aboghazleh R, Mumby G, Veksler R, Ofer J, Newton J, Smith R, Kamintsky L, Jones CMA, O'Keeffe E, Kelly E, Doelle K, Roach I, Yang LT, Moradi P, Lin JM, Gleason AJ, Atkinson C, Bowen C, Brewer KD, Doherty CP, Campbell M, Clarke DB, van Hameren G, Kaufer D, Friedman A.
Publié dans: Brain, 2022, ISSN 1460-2156
Éditeur: Oxford Academic
DOI: 10.1093/brain/awab450

Reversibly Modulating the Blood-Brain Barrier by Laser Stimulation of Molecular-Targeted Nanoparticles.

Auteurs: Li X, Vemireddy V, Cai Q, Xiong H, Kang P, Li X, Giannotta M, Hayenga HN, Pan E, Sirsi SR, Mateo C, Kleinfeld D, Greene C, Campbell M, Dejana E, Bachoo R, Qin Z.
Publié dans: Nano Letters, 2021, ISSN 1530-6984
Éditeur: American Chemical Society
DOI: 10.1021/acs.nanolett.1c02996

SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration

Auteurs: Luke Gibbons; Ema Ozaki; Chris Greene; Anne Trappe; Michael Carty; Judith A. Coppinger; Andrew G. Bowie; Matthew Campbell; Sarah L. Doyle
Publié dans: Frontiers in Neuroscience, Numéro 1, 2022, ISSN 1662-453X
Éditeur: Frontiers
DOI: 10.3389/fnins.2022.852114

Recurrent de novo mutations in CLDN5 induce an anion-selective blood-brain barrier and alternating hemiplegia

Auteurs: Greene C, Hanley N, Reschke CR, Reddy A, Mäe MA, Connolly R, Behan C, O'Keeffe E, Bolger I, Hudson N, Delaney C, Farrell MA, O'Brien DF, Cryan J, Brett FM, Beausang A, Betsholtz C, Henshall DC, Doherty CP, Campbell M.
Publié dans: Brain, 2022, ISSN 1460-2156
Éditeur: Oxford Academic
DOI: 10.1093/brain/awac215

Interleukin-33 regulates metabolic reprogramming of the retinal pigment epithelium in response to immune stressors.

Auteurs: Scott LM, Vincent EE, Hudson N, Neal C, Jones N, Lavelle EC, Campbell M, Halestrap AP, Dick AD, Theodoropoulou S.
Publié dans: JCI Insight, 2021, ISSN 2379-3708
Éditeur: Journal of Clinical Investigation
DOI: 10.1172/jci.insight.129429

Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy.

Auteurs: Reschke CR, Silva LFA, Vangoor VR, Rosso M, David B, Cavanagh BL, Connolly NMC, Brennan GP, Sanz-Rodriguez A, Mooney C, Batool A, Greene C, Brennan M, Conroy RM, Rüber T, Prehn JHM, Campbell M, Pasterkamp RJ, Henshall DC.
Publié dans: Molecular Therapy, 2021, ISSN 1525-0016
Éditeur: Nature Publishing Group
DOI: 10.1016/j.ymthe.2021.02.021

Attenuated CSF-1R signalling drives cerebrovascular pathology

Auteurs: Conor Delaney, Michael Farrell, Colin P Doherty, Kiva Brennan, Eoin O'Keeffe, Chris Greene, Kieva Byrne, Eoin Kelly Niamh Birmingham, Paula Hickey, Simon Cronin, Savvas N Savvides, Sarah L Doyle, Matthew Campbell
Publié dans: EMBO Molecular Medicine, Numéro Feb 5;13(2):e12889, 2021, ISSN 1757-4676
Éditeur: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202012889

Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles

Auteurs: Natalia Muñoz-Wolf , Ross W Ward, Claire H Hearnden, Fiona A Sharp, Joan Geoghegan , Katie O'Grady, Craig P McEntee, Katharine A Shanahan, Coralie Guy, Andrew G Bowie, Matthew Campbell , Carla B Roces, Giulia Anderluzzi, Cameron Webb, Yvonne Perrie, Emma Creagh, Ed C Lavelle
Publié dans: Cell Reports Medicine, 2022, ISSN 2666-3791
Éditeur: Elsevier

Immunohistochemical Analysis of Tight Junction Proteins.

Auteurs: Greene C, Campbell M.
Publié dans: Methods in Molecular Biology, 2022, Page(s) 2022;2492:307-314, ISSN 1064-3745
Éditeur: Springer

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