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CORDIS - Resultados de investigaciones de la UE
CORDIS

Advancing Innovative Stem Cell-based Therapy for Diabetes in Europe

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Dissemination of non-confidential summaries of the project and exploitation plans at prominent biotech conferences, forums and meetings including BioEurope, BioFIT and BIO to promote and establish partnerships relevant to ISLET 3 (se abrirá en una nueva ventana)

Dissemination of nonconfidential summaries of the project and exploitation plans at prominent biotech conferences forums and meetings including BioEurope BioFIT and BIO to promote and establish partnerships relevant to ISLET

Dissemination of non-confidential summaries of the project and exploitation plans at prominent biotech conferences, forums and meetings including BioEurope, BioFIT and BIO to promote and establish partnerships relevant to ISLET 1 (se abrirá en una nueva ventana)

Dissemination of nonconfidential summaries of the project and exploitation plans at prominent biotech conferences forums and meetings including BioEurope BioFIT and BIO to promote and establish partnerships relevant to ISLET

Project website development and launch, ongoing news feed and update about the project, internal project communication of project documents in members area 1 (se abrirá en una nueva ventana)

Project website development and launch ongoing news feed and update about the project internal project communication of project documents in members area

Dissemination of non-confidential summaries of the project and exploitation plans at prominent biotech conferences, forums and meetings including BioEurope, BioFIT and BIO to promote and establish partnerships relevant to ISLET 2 (se abrirá en una nueva ventana)

Dissemination of nonconfidential summaries of the project and exploitation plans at prominent biotech conferences forums and meetings including BioEurope BioFIT and BIO to promote and establish partnerships relevant to ISLET

Building capacity for public engagement at partner institutions: Resources created for digital and face-to-face engagement, initial gap analysis, and to support engagement activities by ISLET 1 (se abrirá en una nueva ventana)

Building capacity for public engagement at partner institutions Resources created for digital and facetoface engagement initial gap analysis and to support engagement activities by ISLET

Report on active participation in European outreach and engagement events 1 (se abrirá en una nueva ventana)

Report on active participation in European outreach and engagement events: network of partner science engagement champions and partner public engagement professionals, ongoing dissemination of local opportunities for engagement and mentoring, contribution to World Diabetes Day (14 November), European City of Science Festival 2022 Leiden, and Long Night of the Sciences across Germany

Publicaciones

A 3D atlas of the human developing pancreas to explore progenitor proliferation and differentiation (se abrirá en una nueva ventana)

Autores: Adrian Villalba, Yorick Gitton, Megumi Inoue, Virginie Aiello, Raphaël Blain, Maryne Toupin, Séverine Mazaud-Guittot, Latif Rachdi, Henrik Semb, Alain Chédotal, Raphaël Scharfmann
Publicado en: Diabetologia, Edición 12 issues a year, 2024, Página(s) 1066–1078, ISSN 0012-186X
Editor: Springer Verlag
DOI: 10.1007/s00125-024-06143-2

Generation of pancreatic β cells from CD177+ anterior definitive endoderm (se abrirá en una nueva ventana)

Autores: Pallavi U. Mahaddalkar, Katharina Scheibner, Sandra Pfluger, Ansarullah, Michael Sterr, Julia Beckenbauer, Martin Irmler, Johannes Beckers, Sebastian Knöbel, Heiko Lickert
Publicado en: Nature Biotechnology, Edición 38/9, 2020, Página(s) 1061-1072, ISSN 1087-0156
Editor: Nature Publishing Group
DOI: 10.1038/s41587-020-0492-5

Synchro-PASEF Allows Precursor-Specific Fragment Ion Extraction and Interference Removal in Data-Independent Acquisition (se abrirá en una nueva ventana)

Autores: Patricia Skowronek, Florian Krohs, [...], and Matthias Mann
Publicado en: Molecular & Cellular Proteomics, 2023, ISSN 1535-9476
Editor: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2022.100489

Making single-cell proteomics biologically relevant (se abrirá en una nueva ventana)

Autores: Rosenberger FA, Thielert M, Mann M.
Publicado en: Nature Methods, 2023, ISSN 1548-7091
Editor: Nature Publishing Group
DOI: 10.1038/s41592-023-01771-9

Stem cell islet replacement in type 1 diabetes: From “shelf” to “self” (se abrirá en una nueva ventana)

Autores: Eelco J.P. de Koning, Françoise Carlotti
Publicado en: Cell Stem Cell, Edición 31, 2024, Página(s) 1727-1729, ISSN 1934-5909
Editor: Cell Press
DOI: 10.1016/j.stem.2024.11.011

A Novel Hybrid High-Speed Mass Spectrometer Allows Rapid Translation From Biomarker Candidates to Targeted Clinical Tests Using 15N-Labeled Proteins (se abrirá en una nueva ventana)

Autores: Maria Wahle, Philip M. Remes, Vincent Albrecht, Michael Baggio Lorenz, Johannes Mueller-Reif, Sophia Steigerwald, Tim Heymann, Lili Niu, Philip Lössl, Stevan Horning, Cristina C. Jacob, Matthias Mann
Publicado en: Molecular & Cellular Proteomics, Edición 24, 2025, Página(s) 101050, ISSN 1535-9476
Editor: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2025.101050

Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome (se abrirá en una nueva ventana)

Autores: Rosenberger FA, Thielert M, Strauss MT, Schweizer L, Ammar C, Mädler SC, Metousis A, Skowronek P, Wahle M, Madden K, Gote-Schniering J, Semenova A, Schiller HB, Rodriguez E, Nordmann TM, Mund A, Mann M.
Publicado en: Nature Methods, 2023, ISSN 1548-7091
Editor: Nature Publishing Group
DOI: 10.1038/s41592-023-02007-6

Engineering islets from stem cells for advanced therapies of diabetes (se abrirá en una nueva ventana)

Autores: Johanna Siehler, Anna Karolina Blöchinger, Matthias Meier, Heiko Lickert
Publicado en: Nature Reviews Drug Discovery, 2021, ISSN 1474-1776
Editor: Nature Publishing Group
DOI: 10.1038/s41573-021-00262-w

A transcriptional cross species map of pancreatic islet cells (se abrirá en una nueva ventana)

Autores: Sophie Tritschler, Moritz Thomas, Anika Böttcher, Barbara Ludwig, Janine Schmid, Undine Schubert, Elisabeth Kemter, Eckhard Wolf, Heiko Lickert, Fabian J. Theis,
Publicado en: Molecular Metabolism,, 2022, ISSN 2212-8778
Editor: Elsevier GmbH
DOI: 10.1016/j.molmet.2022.101595

IMBAS-MS Discovers Organ-Specific HLA Peptide Patterns in Plasma (se abrirá en una nueva ventana)

Autores: Wahle M, Thielert M, Zwiebel M, Skowronek P, Zeng WF, Mann M.
Publicado en: Mol Cell Proteomics, 2024, ISSN 1535-9476
Editor: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2023.100689

Robust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel (se abrirá en una nueva ventana)

Autores: Thielert M, Itang EC, Ammar C, Rosenberger FA, Bludau I, Schweizer L, Nordmann TM, Skowronek P, Wahle M, Zeng WF, Zhou XX, Brunner AD, Richter S, Levesque MP, Theis FJ, Steger M, Mann M.
Publicado en: Mol Syst Biol, 2023, ISSN 1744-4292
Editor: Nature Publishing Group
DOI: 10.15252/msb.202211503

Awaking sleeping islets for a cure of diabetes (se abrirá en una nueva ventana)

Autores: Katharina Scheibner, Heiko Lickert
Publicado en: 2022
Editor: Cell Press
DOI: 10.1016/j.medj.2022.04.004

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