Advancing Innovative Stem Cell-based Therapy for Diabetes in Europe

Risultati finali

Dissemination of non-confidential summaries of the project and exploitation plans at prominent biotech conferences, forums and meetings including BioEurope, BioFIT and BIO to promote and establish partnerships relevant to ISLET 3

Dissemination of nonconfidential summaries of the project and exploitation plans at prominent biotech conferences forums and meetings including BioEurope BioFIT and BIO to promote and establish partnerships relevant to ISLET

Dissemination of non-confidential summaries of the project and exploitation plans at prominent biotech conferences, forums and meetings including BioEurope, BioFIT and BIO to promote and establish partnerships relevant to ISLET 1

Dissemination of nonconfidential summaries of the project and exploitation plans at prominent biotech conferences forums and meetings including BioEurope BioFIT and BIO to promote and establish partnerships relevant to ISLET

Project website development and launch, ongoing news feed and update about the project, internal project communication of project documents in members area 1

Project website development and launch ongoing news feed and update about the project internal project communication of project documents in members area

Dissemination of non-confidential summaries of the project and exploitation plans at prominent biotech conferences, forums and meetings including BioEurope, BioFIT and BIO to promote and establish partnerships relevant to ISLET 2

Dissemination of nonconfidential summaries of the project and exploitation plans at prominent biotech conferences forums and meetings including BioEurope BioFIT and BIO to promote and establish partnerships relevant to ISLET

Building capacity for public engagement at partner institutions: Resources created for digital and face-to-face engagement, initial gap analysis, and to support engagement activities by ISLET 1

Building capacity for public engagement at partner institutions Resources created for digital and facetoface engagement initial gap analysis and to support engagement activities by ISLET

Report on active participation in European outreach and engagement events 1

Report on active participation in European outreach and engagement events: network of partner science engagement champions and partner public engagement professionals, ongoing dissemination of local opportunities for engagement and mentoring, contribution to World Diabetes Day (14 November), European City of Science Festival 2022 Leiden, and Long Night of the Sciences across Germany

Pubblicazioni

A 3D atlas of the human developing pancreas to explore progenitor proliferation and differentiation

Autori: Adrian Villalba, Yorick Gitton, Megumi Inoue, Virginie Aiello, Raphaël Blain, Maryne Toupin, Séverine Mazaud-Guittot, Latif Rachdi, Henrik Semb, Alain Chédotal, Raphaël Scharfmann
Pubblicato in: Diabetologia, Numero 12 issues a year, 2024, Pagina/e 1066–1078, ISSN 0012-186X
Editore: Springer Verlag
DOI: 10.1007/s00125-024-06143-2

Generation of pancreatic β cells from CD177+ anterior definitive endoderm

Autori: Pallavi U. Mahaddalkar, Katharina Scheibner, Sandra Pfluger, Ansarullah, Michael Sterr, Julia Beckenbauer, Martin Irmler, Johannes Beckers, Sebastian Knöbel, Heiko Lickert
Pubblicato in: Nature Biotechnology, Numero 38/9, 2020, Pagina/e 1061-1072, ISSN 1087-0156
Editore: Nature Publishing Group
DOI: 10.1038/s41587-020-0492-5

Synchro-PASEF Allows Precursor-Specific Fragment Ion Extraction and Interference Removal in Data-Independent Acquisition

Autori: Patricia Skowronek, Florian Krohs, [...], and Matthias Mann
Pubblicato in: Molecular & Cellular Proteomics, 2023, ISSN 1535-9476
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2022.100489

Making single-cell proteomics biologically relevant

Autori: Rosenberger FA, Thielert M, Mann M.
Pubblicato in: Nature Methods, 2023, ISSN 1548-7091
Editore: Nature Publishing Group
DOI: 10.1038/s41592-023-01771-9

Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome

Autori: Rosenberger FA, Thielert M, Strauss MT, Schweizer L, Ammar C, Mädler SC, Metousis A, Skowronek P, Wahle M, Madden K, Gote-Schniering J, Semenova A, Schiller HB, Rodriguez E, Nordmann TM, Mund A, Mann M.
Pubblicato in: Nature Methods, 2023, ISSN 1548-7091
Editore: Nature Publishing Group
DOI: 10.1038/s41592-023-02007-6

Engineering islets from stem cells for advanced therapies of diabetes

Autori: Johanna Siehler, Anna Karolina Blöchinger, Matthias Meier, Heiko Lickert
Pubblicato in: Nature Reviews Drug Discovery, 2021, ISSN 1474-1776
Editore: Nature Publishing Group
DOI: 10.1038/s41573-021-00262-w

A transcriptional cross species map of pancreatic islet cells

Autori: Sophie Tritschler, Moritz Thomas, Anika Böttcher, Barbara Ludwig, Janine Schmid, Undine Schubert, Elisabeth Kemter, Eckhard Wolf, Heiko Lickert, Fabian J. Theis,
Pubblicato in: Molecular Metabolism,, 2022, ISSN 2212-8778
Editore: Elsevier GmbH
DOI: 10.1016/j.molmet.2022.101595

IMBAS-MS Discovers Organ-Specific HLA Peptide Patterns in Plasma

Autori: Wahle M, Thielert M, Zwiebel M, Skowronek P, Zeng WF, Mann M.
Pubblicato in: Mol Cell Proteomics, 2024, ISSN 1535-9476
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2023.100689

Robust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel

Autori: Thielert M, Itang EC, Ammar C, Rosenberger FA, Bludau I, Schweizer L, Nordmann TM, Skowronek P, Wahle M, Zeng WF, Zhou XX, Brunner AD, Richter S, Levesque MP, Theis FJ, Steger M, Mann M.
Pubblicato in: Mol Syst Biol, 2023, ISSN 1744-4292
Editore: Nature Publishing Group
DOI: 10.15252/msb.202211503

Awaking sleeping islets for a cure of diabetes

Autori: Katharina Scheibner, Heiko Lickert
Pubblicato in: 2022
Editore: Cell Press
DOI: 10.1016/j.medj.2022.04.004

Risultati finali

Pubblicazioni

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