CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.
Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.
Leistungen
Highresolution images of endometrial and myometrial sections immunohistochemically stained with cell typespecific markers
HUTER Workshop (öffnet in neuem Fenster)Virtual reality Microscopy tool. (öffnet in neuem Fenster)
Virtual reality Microscopy tool
Deployment HUTER cloud infrastructure (öffnet in neuem Fenster)Deployment of HUTER cloud infrastructure
High-resolution spatial image maps (öffnet in neuem Fenster)Highresolution spatial image maps of different cell states in human endometrium and myometrium across lifespan
Spatial transcriptomics (öffnet in neuem Fenster)Dataset of spatial transcriptomics of endometrium and myometrium
HUTER collection completed (öffnet in neuem Fenster)HUTER collection completed with specimen storage for each donor and tissue type
Visual system & Digitalisation software (öffnet in neuem Fenster)Visual System implemented and Digitalisation software to transform images from research equipment under opensource standards
Cell type-specific protein expression patterns (öffnet in neuem Fenster)Dataset of cell typespecific protein expression patterns in human endometrium and myometrium across lifespan
Data access and DICOM visualization tools (öffnet in neuem Fenster)Final implementation of data access tools and DICOM visualization tool
Validated HUTER platform (öffnet in neuem Fenster)Validated HUTER platform accessible for use by the scientific community with activated measures to ensure its sustainability after projectend
Description of SOP for tissue collection and processing, agreed by all partners responsible for tissue procurement
DICOM implementation (öffnet in neuem Fenster)Report on the full DICOM implementation standard
Dissemination & Exploitation plan 2 (öffnet in neuem Fenster)Plan for the Dissemination Exploitation of Results Dissemination Toolkit 2 Industry consultations Record of dissemination and communication activities in year 1 and plan for year 2 project leaflets and posters audiovisual material Planning for the HUTER Workshop
Tissue specimens description (öffnet in neuem Fenster)Description of the tissue specimens used once the tissue procurement phase is finalised
Platform architecture design (öffnet in neuem Fenster)Platform architecture design, interconnectivity aspects and standards to use, fully aligned with the HCA guidelines
Final design of HUTER platform (öffnet in neuem Fenster)Final design of HUTER platform architecture
Record on the Dissemination, Exploitation, IPR (öffnet in neuem Fenster)Record on the Dissemination Exploitation and IPR activities in the project
Methylation atlas (öffnet in neuem Fenster)Generate a methylation atlas for normal endometrium and myometrium tissues cataloguing specific cell types
New cell states (öffnet in neuem Fenster)Report on identified new cell states and cell to cell communication mechanisms
Dissemination & Exploitation plan 1 (öffnet in neuem Fenster)Plan for the Dissemination Exploitation of Results Dissemination Toolkit 1 Industry consultations First year plan for dissemination and communication activities Website first industry consultations and dissemination toolkit 1
Data set of 1 mil scRNAseq for endometrium cells at reproductive age to assess variability among individuals
~1 mil scRNAseq for myometrium (öffnet in neuem Fenster)Data set of 1 mil scRNAseq for myometrium cells across the lifespan
Single-cell whole genome sequencing (öffnet in neuem Fenster)Whole genome sequencing for all healthy study population
~1 mil scRNAseq for endometrium (öffnet in neuem Fenster)Data set of 1 mil scRNAseq for endometrium cells across the lifespan
Veröffentlichungen
Autoren:
Luz Garcia-Alonso, Louis-François Handfield, Kenny Roberts, Konstantina Nikolakopoulou, Ridma C. Fernando, Lucy Gardner, Benjamin Woodhams, Anna Arutyunyan, Krzysztof Polanski, Regina Hoo, Carmen Sancho-Serra, Tong Li, Kwasi Kwakwa, Elizabeth Tuck, Valentina Lorenzi, Hassan Massalha, Martin Prete, Vitalii Kleshchevnikov, Aleksandra Tarkowska, Tarryn Porter, Cecilia Icoresi Mazzeo, Stijn van Donge
Veröffentlicht in:
Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro, Ausgabe Nat Genet 53 (2021), 2021, Seite(n) 1698–1711, ISSN 1061-4036
Herausgeber:
Nature Publishing Group
DOI:
10.1038/s41588-021-00972-2
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