Tracing epigenetic evolution of triple-negative breast cancer towards chemo-resistance

Project Information

ChromTrace

Grant agreement ID: 948528

DOI

10.3030/948528

Project closed

EC signature date 9 November 2020

Start date 1 January 2021

End date 30 November 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Other (1)

Identification of a shared persistence program in triple-negative breast cancer across treatments and patients

Author(s): Léa Baudre, Grégoire Jouault, Pacôme Prompsy, Melissa Saichi, Sarah Gastineau, Christophe Huret, Laura Sourd, Ahmed Dahmani, Elodie Montaudon, Florent Dingli, Damarys Loew, Elisabetta Marangoni, Justine Marsolier, Céline Vallot
Published in: Cancer Research, 2025
Publisher: BioRxiv
DOI: 10.1101/2025.03.17.643634

Peer reviewed articles (6)

H3K27me3 conditions chemotolerance in triple-negative breast cancer

Author(s): Justine Marsolier, Pacôme Prompsy, Adeline Durand, Anne-Marie Lyne, Camille Landragin, Amandine Trouchet, Sabrina Tenreira Bento, Almut Eisele, Sophie Foulon, Léa Baudre, Kevin Grosselin, Mylène Bohec, Sylvain Baulande, Ahmed Dahmani, Laura Sourd, Eric Letouzé, Anne-Vincent Salomon, Elisabetta Marangoni, Leïla Perié & Céline Vallot
Published in: Nature Genetics, 2022, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-022-01047-6

Epigenomic disorder and partial EMT impair luminal progenitor integrity in Brca1-associated breast tumorigenesis

Author(s): Camille Landragin, Melissa Saichi, Marthe Laisné, Adeline Durand, Pacôme Prompsy, Renaud Leclere, Jérémy Mesple, Kyra Borgman, Amandine Trouchet, Marisa M. Faraldo, Aurélie Chiche, Anne Vincent-Salomon, Hélène Salmon, Céline Vallot
Published in: Molecular Cancer, Issue 24, 2025, ISSN 1476-4598
Publisher: BioMed Central
DOI: 10.1186/s12943-025-02331-9

Epigenomic heterogeneity as a source of tumour evolution

Author(s): Marthe Laisné, Mathieu Lupien, Céline Vallot
Published in: Nature Reviews Cancer, Issue 25, 2024, Page(s) 7-26, ISSN 1474-175X
Publisher: Nature Publishing Group
DOI: 10.1038/s41568-024-00757-9

A benchmark of computational pipelines for single-cell histone modification data

Author(s): Félix Raimundo, Pacôme Prompsy, Jean‐Philippe Vert and Céline Vallot
Published in: Genome Biology, 2023, ISSN 1474-760X
Publisher: BioMed Central
DOI: 10.1186/s13059-023-02981-2

Multi-modal quantification of pathway activity with MAYA

Author(s): Yuna Landais, Céline Vallot
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-37410-2

IDclust: Iterative clustering for unsupervised identification of cell types with single cell transcriptomics and epigenomics

Author(s): Pacôme Prompsy, Mélissa Saichi, Félix Raimundo, Céline Vallot
Published in: NAR Genomics and Bioinformatics, Issue 6, 2025, ISSN 2631-9268
Publisher: Oxford University Press (OUP)
DOI: 10.1093/nargab/lqae174

Book chapters (1)

Single-cell Epigenomic Profiling with High-throughput Droplet scChIP-seq

Author(s): Justine Marsolier, Eve Moutaux, Kevin Grosselin, Andrew Griffiths, Céline Vallot
Published in: Methods in Molecular Biology, Histones, 2025, Page(s) 213-239
Publisher: Springer US
DOI: 10.1007/978-1-0716-4486-7_12