BoneFix: A Paradigm Shift in Fracture Fixations via On-Site Fabrication of Bone Restoration Patches

Project Information

BoneFix

Grant agreement ID: 952150

DOI 10.3030/952150

EC signature date 24 June 2020

Start date 1 October 2020

End date 30 September 2024

Funded under

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Total cost € 3 983 468,13

EU contribution € 3 983 468,13

Coordinated by

KUNGLIGA TEKNISKA HOEGSKOLAN
Sweden

Deliverables

Websites, patent fillings, videos etc. (2)

Training media

Videos aimed at surgeons describing the application and advantages of BoneFix

Project website

BMB will establish and update the project website in conjunction with the project coordinator The website will be continuously updated with publishable reports and other information relevant to stakeholders and the broader public

Publications

Conference proceedings (9)

Dendritic-Linear-Dendritic (DLD) Based Materials and Their Potential Use inBiomedical Applications

Author(s): Molina, Noemi; Sanz del Olmo, Natalia; Hutchinson, Daniel J.; Malkoch, Michael
Published in: ARI Abstracts Periodical, Issue 3, 2023, Page(s) 177, ISSN 2960-2483
Publisher: AO Research Institute Davos

Strong photo-curable thiol-ene based composites for use in the fixation of bonefractures

Author(s): Hutchinson, Daniel J.; Granskog, Viktor; Malkoch, Michael
Published in: ARI Abstracts Periodical, Issue 3, 2023, Page(s) 153, ISSN 2960-2483
Publisher: AO Research Institute Davos

Degradable thiol-ene composites for bone repair

Author(s): San Jacinto, Jorge; Hutchinson, Daniel J.; Sanz del Olmo, Natalia; Malkoch, Michael
Published in: ARI Abstracts Periodical, Issue 3, 2023, Page(s) 303, ISSN 2960-2483
Publisher: AO Research Institute Davos

Fabrication of biodegradable high strength and shape-shifting polylactic acidmembrane for reinforcement of a photo-curable composite bone fixation patch

Author(s): Patt-Lafitte, Guillaume; Hutchinson, Daniel J.; Malkoch, Michael; Eglin, David
Published in: ARI Abstracts Periodical, Issue 3, 2023, Page(s) 462, ISSN 2960-2483
Publisher: AO Research Institute Davos

Welfare monitoring in the novel ovine thoracic limb, bilateral, single-toeostectomy model (OBST)

Author(s): Nikolaisen, Nannet Kvist.; Tierp-Wong, Christian Nai En.; Colding-Rasmussen, Thomas; Petersen, Michael Mork; Hutchinson, Daniel; Lindegaard, Casper; Jacobsen, Stine
Published in: ARI Abstracts Periodical, Issue 3, 2023, Page(s) 144, ISSN 2960-2483
Publisher: AO Research Insitute Davos

Biomechanical analysis of a novel osteosynthesis device with standard andphysiological testing

Author(s): Schwarzenberg, Peter; Colding-Rasmussen, Thomas; Hutchinson, Daniel J.; San Jacinto Garcia, Jorge; Jacobsen, Stine; Horstmann, Peter; Petersen, Michael Mork; Mischler, Dominic; Granskog, V.; Pastor, Tatjana; Weis, Tine; Malkoch, Michael; Wong, Christian; Varga, Peter
Published in: ARI Abstracts Periodical, Issue 3, 2023, Page(s) 314, ISSN 2960-2483
Publisher: AO Research Institute Davos

The effect of PET meshes on the mechanical and structural properties of a photo-curable hydroxyapatite composite intended as internal fixation in complex bonefractures

Author(s): Patt-Lafitte, Guillaume, Rasolonjatovo, Sarah; Hutchinson, Daniel J.; Malkoch, Michael; Eglin, David
Published in: ARI Abstracts Periodical, Issue 3, 2023, Page(s) 228, ISSN 2960-2483
Publisher: AO Research Institute Davos

Cytocompatibility and osteogenic differentiation of mesenchymal stem cellswithin phototunable polyester-based PEGylated dendritic hydrogels

Author(s): Torelli, Francesco; Mohamed-Ahmed, Samih; Rashad, Ahmad; Cabeza, Noemi M.; Hutchinson, Daniel J.; Malkoch, Michael; Mustafa, Kamal
Published in: ARI Abstracts Periodical, Issue 3, 2023, Page(s) 492, ISSN 2960-2483
Publisher: AO Research Institute Davos

From bench to chairside: Mesenchymal stem cells and biomedical engineering inbone regeneration

Author(s): Mustafa, Kamal E.
Published in: ARI Abstracts Periodical, Issue 3, 2023, Page(s) 312, ISSN 2960-2483
Publisher: AO Research Institute Davos

Peer reviewed articles (7)

Biomechanical Performance of a Novel-Curable Bone Fixation Technique

Author(s): Schwarzenberg, Peter; Colding-Rasmussen, Thomas; Hutchinson, Daniel J; Mischler, Dominic; Horstmann, Peter; Petersen, Michael Meork; Jacobsen, Stine; Pastor, Tatjana; Malkock, Michael; Wong, Christian; Varga, Peter
Published in: Scientific Reports, Issue 13, 2023, Page(s) 9339, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-35706-3

Biomechanical Variability and Usability of a Novel Customizable Fracture Fixation Technique

Author(s): Colding-Rasmussen, Thomas; Schwarzenberg, Peter; Horstmann, Peter Frederik; Ottesen, Casper Bent Smedegaard; Garcia, Jorge San Jacinto; Hutchinson, Daniel John; Malkoch, Michael; Petersen, Michael Mørk; Varga, Peter; Tierp-Wong, Christian Nai En
Published in: Bioengineering, Issue 10, 2023, Page(s) 1146, ISSN 2306-5354
Publisher: MDPI
DOI: 10.3390/bioengineering10101146

Soft Hydroxyapatite Composites Based on Triazine–Trione Systems as Potential Biomedical Engineering Frameworks

Author(s): Lin, Jinjian; Fan, Yanmiao; Hutchinson, Daniel J.; Malkoch, Michael
Published in: ACS Appl Mater Interfaces, Issue 15, 2023, Page(s) 7329-7339, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.2c16235

Impact of Polyester Dendrimers as Branched Multifunctional Cross-Linking Additives in Triazine-Trione-Based Composites Developed via High-Energy Visible Light Thiol-ene Chemistry

Author(s): Lin, Jinjian; Sanz del Olmo, Natalia; San Jacinto Garcia, Jorge; Hutchinson, Daniel J.; Malkoch, Michael
Published in: ACS Applied Polymer Materials, Issue 5, 2023, Page(s) 10395-10403, ISSN 2637-6105
Publisher: American Chemical Society
DOI: 10.1021/acsapm.3c02246

Synthesis and Characterization of Amino-Functional Polyester Dendrimers Based On Bis-MPA with Enhanced Hydrolytic Stability and Inherent Antibacterial Properties

Author(s): Namata, Faridah; Sanz del Olmo, Natalia; Molina, Noemi; Malkoch, Michael
Published in: Biomacromolecules, Issue 24, 2023, Page(s) 858-867, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.2c01286

Antibacterial Hydrogel Adhesives Based on Bifunctional Telechelic Dendritic-Linear–Dendritic Block Copolymers

Author(s): Sanz del Olmo, Natalia; Molina, Noemi; Fan, Yanmiao; Hutchinson, Daniel J.; Malkoch, Michael
Published in: J. Am. Chem. Soc., Issue 146, 2024, Page(s) 17240-17249, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.4c03673

Toughening and strengthening of visible light-cured hydroxyapatite thiol-ene resin composite intended as bone fixation using 2D textile

Author(s): Patt-Lafitte, Guillaume; Valfort, Oliver; Hutchinson, Daniel J.; Malkoch, Michael; Eglin, David
Published in: Journal of Materials Research and Technology, Issue 29, 2024, Page(s) 982-990, ISSN 2238-7854
Publisher: Elsevier Editora Ltda
DOI: 10.1016/j.jmrt.2024.01.127