Boosting advanced doctoral training in innovative colon targeting drugs

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Mid-term report WP 3

Midterm report summarizing WP3 ESRs results

Mid-term report WP 2

Midterm report summarizing WP2 ESRs results

Mid-term report WP 1

Midterm report summarizing WP1 ESRs results

List of recruited ESRs

list of recruited ESRs

Project management handbook

Project management handbook and quality assurance

Reports on transferable skills

Reports on transferable skills acquired by ESRs (network-wide and local training)

Communication package

Communication package website graphical charts templates social networks

Pubblicazioni

Solidification and oral delivery of biologics to the colon- A review

Autori: Kopp, Katharina Tatjana; Saerens, Lien; Voorspoels, Jody; Mooter, Guy Van den
Pubblicato in: European Journal of Pharmaceutical Sciences, 2023, ISSN 1879-0720
Editore: Elsevier
DOI: 10.1016/j.ejps.2023.106523

Selective Serotonin Reuptake Inhibitors Within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane

Autori: A. L. Nichols, Z. Blumenfeld, L. Luebbert, H. J. Knox, A. K. Muthusamy, J. S. Marvin, C. H. Kim, S. N. Grant, D. P. Walton, B. N. Cohen, R. Hammar, L. L. Looger, P. Artursson, D. A. Dougherty, H. A. Lester
Pubblicato in: Journal of Neuroscience, 2023, ISSN 1529-2401
Editore: Journal of Neuroscience
DOI: 10.1101/2022.08.09.502705

Spray drying for protein stabilization

Autori: Katharina Tatjana Kopp, Maarten De Beer, Jody Voorspoels, Dorien Van Lysebetten, Guy Van den Mooter
Pubblicato in: International Journal of Pharmaceutics, Numero 677, 2025, Pagina/e 125600, ISSN 0378-5173
Editore: Elsevier BV
DOI: 10.1016/j.ijpharm.2025.125600

Human organotypic colon in vitro microtissue: unveiling a new window into colonic drug disposition

Autori: Pedro G.M. Canhão, Jan Snoeys, Suzy Geerinckx, Marjolein van Heerden, An Van den Bergh, Camden Holm, Jan Markus, Seyoum Ayehunie, Mario Monshouwer, Raymond Evers, Patrick Augustijns, Stephanie Kourula
Pubblicato in: European Journal of Pharmaceutical Sciences, 2025, Pagina/e 107025, ISSN 0928-0987
Editore: Elsevier BV
DOI: 10.1016/j.ejps.2025.107025

Managing the clinical effects of drug-induced intestinal dysbiosis with a focus to antibiotics: Challenges and opportunities

Autori: Lea Gnatzy; George Ismailos; Maria Vertzoni; Christos Reppas
Pubblicato in: European Journal of Pharmaceutical Sciences, 2023, ISSN 1879-0720
Editore: Elsevier
DOI: 10.1016/j.ejps.2023.106510

Epithelial and microbial determinants of colonic drug distribution

Autori: R. Hammar, M. E. Sellin, P. Artursson
Pubblicato in: European Journal of Pharmaceutical Sciences, 2023, ISSN 1879-0720
Editore: Elsevier
DOI: 10.1016/j.ejps.2023.106389

Development of a canine artificial colonic mucus model for drug diffusion studies

Autori: V. Barmpatsalou, M. Tjakra, L. Li, I.R. Dubbelboer, E. Karlsson, B. Pedersen Lomstein, C.A.S. Bergström
Pubblicato in: European journal of pharmaceutical sciences, 2024, ISSN 1879-0720
Editore: Elsevier
DOI: 10.1016/j.ejps.2024.106702

Disease‐Adaptive Drug Delivery to the Inflamed Intestinal Mucosa Using Poly(Lactic‐<i>Co</i>‐Glycolic Acid)‐cyclodextrin Hybrid Nanocarriers

Autori: Jonas Schreiner, Felix E. B. Brettner, Sebastian Steigert, Annika Haessler, Raf Mols, Stefanie Gier, Nathalie Jung, Sarah Vogel‐Kindgen, Susanne Muschert, Patrick Augustijns, Maike Windbergs
Pubblicato in: Advanced Therapeutics, 2025, ISSN 2366-3987
Editore: Wiley
DOI: 10.1002/adtp.202400368

The value of spray drying as stabilization process for proteins

Autori: Katharina Tatjana Kopp, Maarten De Beer, Jody Voorspoels, Dorien Van Lysebetten, Guy Van den Mooter
Pubblicato in: International Journal of Pharmaceutics, Numero 674, 2025, Pagina/e 125422, ISSN 0378-5173
Editore: Elsevier BV
DOI: 10.1016/j.ijpharm.2025.125422

Exploring the potential of human intestinal organoids: Applications, challenges, and future directions

Autori: Inês A. Parente, Linda Chiara, Simona Bertoni
Pubblicato in: Life Sciences, Numero 352, 2024, Pagina/e 122875, ISSN 0024-3205
Editore: Elsevier BV
DOI: 10.1016/j.lfs.2024.122875

Do probiotic interventions improve female unexplained infertility? A critical commentary

Autori: Alessia Favaron; Engin Turkgeldi; Moe Elbadawi; Simon Gaisford; Abdul W. Basit; Mine Orlu
Pubblicato in: Reproductive Biomedicine Online, 2024, ISSN 1472-6491
Editore: Elsevier
DOI: 10.1016/j.rbmo.2023.103734

Can in vitro/in silico tools improve colonic concentration estimations for oral extended-release formulations? A case study with upadacitinib

Autori: Alessia Favaron, Bart Hens, Maiara Camotti Montanha, Mark McAllister, Irena Tomaszewska, Shaimaa Moustafa, Marília Alvarenga de Oliveira, Abdul W. Basit, Mine Orlu
Pubblicato in: Journal of Controlled Release, Numero 370, 2024, Pagina/e 182-194, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2024.04.024

Approaches to Account for Colon Absorption in Physiologically Based Biopharmaceutics Modeling of Extended-Release Drug Products

Autori: Harshad Jadhav; Patrick Augustijns; Christer Tannergren
Pubblicato in: Molecular Pharmaceutics, 2023, ISSN 1543-8392
Editore: ACS Publication
DOI: 10.1021/acs.molpharmaceut.3c00683

Ai’s role in colon-targeted drug delivery

Autori: Alessia Favaron, Youssef Abdalla, Abdul Basit, Mine Orlu
Pubblicato in: Expert Opinion on Drug Delivery, 2025, ISSN 1742-5247
Editore: Ashley Publications Ltd.
DOI: 10.1080/17425247.2025.2465769

Physiologically Based Biopharmaceutics Modeling of Regional and Colon Absorption in Humans

Autori: Christer Tannergren; Harshad Jadhav; Emma Eckernäs; Jonas Fagerberg; Patrick Augustijns; Erik Sjögren
Pubblicato in: European Journal of Pharmaceutics and Biopharmaceutics, 2023, Pagina/e 144-159, ISSN 0939-6411
Editore: Elsevier BV
DOI: 10.2139/ssrn.4358310

Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics

Autori: L. E. McCoubrey, A. Favaron, A. Awad, M. Orlu, S. Gaisford, A. W. Basit
Pubblicato in: Journal of Controlled Release 2023, 2023, Pagina/e 1107-1126, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2022.12.029

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Risultati finali

Pubblicazioni

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