CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.
I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .
Risultati finali
The deliverable will consist in a report on the synthesis of hybrid hard organosilica NPs that are cleaved in the presence of specific biomolecules and are able to allow the cargo release
Report on EVs derived from tumor/osteoblastic cells ready and characterizedThe deliverable will consist of a report describing the tumorosteoblastic cells chosen as source of EVs and of the protocols used for EV extraction and characterization and related results
Quantitative estimation of protein numbers and distribution for EVsThe deliverable will consist of a report containing the following parameters: i) size of EVs; ii) number of multiple surface protein per EV; iii) the distribution of these quantities in the EV population.
Kick-off meeting reportReport on the kickoff meeting describing the coordination and partners roles organization of the consortium and of the research work
Selection of 2 natural EVs bone-targeting candidatesA report describing the use of natural EVs containing CTSK RANKL or other bone targeting candidates for in vivo application on healthy mice to evaluate the biodistribution
Website creation and continuous update planningsSocial profiles creation and pages actions and planning for the dissemination to broad publics logo creation and planning for its use
The deliverable will consist in a report on modelling and simulations to compare the dynamics of lipid bilayers having the inner leaflet bound to the hard-core NP surface
Molecular models and simulations for lipid-covered hard-core NPs with different geometriesThe deliverable will consist in in a report on modelling and simulations to compare the dynamics of lipid bilayers in perfect/flat domains vs. in the presence of discontinuities/edges at the NP surface (NP shape effect)
Molecular models and simulations for EV lipid bilayer envelopesThe deliverable will consist in a report on the modelling and simulations to characterize the dynamics and stability of various EV lipid bilayers envelops.
Pubblicazioni
Autori:
Charly Empereur-mot, Riccardo Capelli, Mattia Perrone, Cristina Caruso, Giovanni Doni, Giovanni M. Pavan
Pubblicato in:
J. Chem. Phys, Numero 156, 2022, ISSN 0021-9606
Editore:
American Institute of Physics
DOI:
10.1063/5.0079044
Autori:
María Sancho-Albero, Giada Rosso, Luisa De Cola, Valentina Cauda
Pubblicato in:
Nanoscale, Numero 15, 2023, Pagina/e 14628-14640, ISSN 2040-3372
Editore:
Royal Society of Chemistry
DOI:
10.1039/d3nr02155f
Autori:
Giada Rosso, Valentina Cauda
Pubblicato in:
ACS Biomater. Sci. Eng., Numero 2023, 9, 11, 2023, Pagina/e 5924–5932, ISSN 2373-9878
Editore:
American Chemical Society
DOI:
10.1021/acsbiomaterials.2c01025
Autori:
Nicolò Maria Percivalle; Marco Carofiglio; Marzia Conte; Giada Rosso; Alessandro Bentivogli; Giulia Mesiano; Veronica Vighetto; Valentina Cauda
Pubblicato in:
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Numero 23 (15815), 2022, Pagina/e 1-28, ISSN 1422-0067
Editore:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ijms232415815
Autori:
Marzia Conte; Marco Carofiglio; Giada Rosso; Valentina Cauda
Pubblicato in:
Nanomaterials; Volume 13; Numero 15; Pages: 2250, Numero 4, 2023, ISSN 2079-4991
Editore:
MDPI
DOI:
10.3390/nano13152250
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