Descripción del proyecto
Cuidados proactivos y personalizados para enfermedades crónicas complejas
La atención oportuna y preventiva son fundamentales para las enfermedades crónicas complejas (ECC) con morbilidad múltiple, las cuales son muy prevalentes en pacientes con enfermedad pulmonar obstructiva crónica, una enfermedad pulmonar crónica. El proyecto financiado con fondos europeos RE-SAMPLE desarrollará un tratamiento dirigido y una atención preventiva, integradora y basada en pruebas, lo que permitirá «tratar la persona y no la enfermedad». Una base de conocimientos de datos multimodales (historiales clínicos, estudios clínicos y datos de la vida real) junto con una modelización predictiva a través de inteligencia artificial basada en la preservación de la privacidad aumentarán nuestros conocimientos sobre las ECC. Estos conocimientos se incorporarán a un programa de acompañamiento virtual que facilita la toma de decisiones compartida y se aplicará en tres hospitales europeos. En general, RE-SAMPLE trabaja de cara a un método personalizado y diversificado que reduzca la carga social y económica de las ECC.
Objetivo
Multi-morbid complex chronic conditions (CCCs) are highly prevalent in patients with Chronic Obstructive Pulmonary Disease (COPD). As they have common risk factors and overlapping symptoms, this easily leads to delay of appropriate treatment. Timely and preventive care is essential, as exacerbations of COPD and CCCs are detrimental to patient, health and social outcomes. RE-SAMPLE will take a giant leap in the field of CCC disease management building upon and going beyond existing initiatives, towards evidence-based, inclusive, preventive care and targeted treatment, enabling to “treat a person, not the disease(s)”. RE-SAMPLE will create a knowledge base of multimodal data from health records, clinical studies, expert and patient knowledge and guidelines, and extend this with state-of-the-art Real World Data collection. Predictive modelling through privacy-preserving Artificial Intelligence (AI), will increase the understanding of CCCs including the interdependence of multi-morbidities, and evidence in effective interventions for CCC disease management. The inclusive design and citizen science approach, provides us with credible and accepted RWD tools and a patient-centred eHealth “companionship programme”. GDPR-compliance is carefully integrated from the beginning, and our platform allows for a strong advancement in secure algorithms using multi-party computation. Our AI approach enables statistical validation following clinical standards and useful explanations to build up clinical evidence and trust by the users. As such RE-SAMPLE will act upon the need for diversified, personalized care to alleviate the overall societal and economic burden of these CCCs. The RE-SAMPLE project significantly impact towards this direction not only through the development of the platform and companionship programme, but also through its implementation throughout Europe, enabling and guiding healthcare organizations its uptake in the privacy-sensitive domain of healthcare.
Ámbito científico
Palabras clave
Programa(s)
Convocatoria de propuestas
Consulte otros proyectos de esta convocatoriaConvocatoria de subcontratación
H2020-SC1-2020-Single-Stage-RTD
Régimen de financiación
RIA - Research and Innovation actionCoordinador
7522 NB Enschede
Países Bajos