Descrizione del progetto
Cure proattive e su misura per condizioni croniche complesse
Cure tempestive e preventive sono essenziali per condizioni croniche complesse multi morbose, estremamente prevalenti in pazienti affetti da broncopneumopatia cronica ostruttiva, una malattia polmonare cronica. Il progetto RE-SAMPLE, finanziato dall’UE, svilupperà cure e un trattamento mirato basati sulle evidenze, inclusivi e preventivi, rendendo possibile «il trattamento della persona, non della/e malattia/e». Una base di conoscenze di dati multimodali (cartelle cliniche, studi clinici e dati del mondo reali), assieme a una modellizzazione predittiva attraverso un’intelligenza artificiale rispettosa della riservatezza, incrementeranno la comprensione delle condizioni croniche complesse. Queste conoscenze sono incorporate in un programma di compagnia virtuale che facilita il processo decisionale condiviso, attuato in tre ospedali europei. Nel complesso, il progetto RE-SAMPLE lavora a un metodo di cura diversificato e personalizzato che riduca l’onere sociale ed economico delle condizioni croniche complesse.
Obiettivo
Multi-morbid complex chronic conditions (CCCs) are highly prevalent in patients with Chronic Obstructive Pulmonary Disease (COPD). As they have common risk factors and overlapping symptoms, this easily leads to delay of appropriate treatment. Timely and preventive care is essential, as exacerbations of COPD and CCCs are detrimental to patient, health and social outcomes. RE-SAMPLE will take a giant leap in the field of CCC disease management building upon and going beyond existing initiatives, towards evidence-based, inclusive, preventive care and targeted treatment, enabling to “treat a person, not the disease(s)”. RE-SAMPLE will create a knowledge base of multimodal data from health records, clinical studies, expert and patient knowledge and guidelines, and extend this with state-of-the-art Real World Data collection. Predictive modelling through privacy-preserving Artificial Intelligence (AI), will increase the understanding of CCCs including the interdependence of multi-morbidities, and evidence in effective interventions for CCC disease management. The inclusive design and citizen science approach, provides us with credible and accepted RWD tools and a patient-centred eHealth “companionship programme”. GDPR-compliance is carefully integrated from the beginning, and our platform allows for a strong advancement in secure algorithms using multi-party computation. Our AI approach enables statistical validation following clinical standards and useful explanations to build up clinical evidence and trust by the users. As such RE-SAMPLE will act upon the need for diversified, personalized care to alleviate the overall societal and economic burden of these CCCs. The RE-SAMPLE project significantly impact towards this direction not only through the development of the platform and companionship programme, but also through its implementation throughout Europe, enabling and guiding healthcare organizations its uptake in the privacy-sensitive domain of healthcare.
Campo scientifico
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Invito a presentare proposte
Vedi altri progetti per questo bandoBando secondario
H2020-SC1-2020-Single-Stage-RTD
Meccanismo di finanziamento
RIA - Research and Innovation actionCoordinatore
7522 NB Enschede
Paesi Bassi