Obiettivo This project will focus on the stimulation of a protective immune response in fish, the understanding of the mechanisms involved and further the ability to design optimal vaccines allowing a high protective immunity. Two fish species will be studied: salmonids (rainbow trout, Oncorhyncus mykiss, and salmon, Salmo salar) and cypronids (carp, Cyprinus carpio L.), and immune stimulation will be performed with two viral pathogens: the SVC virus (Spring Viremia of Carp) and the VHS virus (Viral Haemorrhagic Septicemia) infecting salmonids. We will use in particular a well characterized antigen from these viruses, the G protein which will be produced in microorganisms and purified. The stimulation of a protective immune response is divided into various essential steps that requires multi-disciplinary analysis: antibody production, antigen presentation, B-cells stimulation and T-cells functions, cytotoxicity, and cytokine-mediated response. These studies will lead to the determination of the best immunisation and design of optimal immunogens for fish vaccination. Campo scientifico agricultural sciencesagriculture, forestry, and fisheriesfisheriesmedical and health sciencesbasic medicineimmunologyimmunisationnatural sciencesbiological sciencesmicrobiologyvirologymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccinesnatural sciencesbiological scienceszoologyichthyology Programma(i) FP3-AIR - Specific research and technological development and demonstration programme (EEC) in the field of agriculture and agro-industry, including fisheries, 1990-1994 Argomento(i) 251 - Health of aquacultural stocks Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore SOCIETE EUROPEENNE DE BIOTECHNOLOGIE S.A. Contributo UE Nessun dato Indirizzo RUE BOIS SAINT JEAN 14 4102 SERAING Belgio Mostra sulla mappa Costo totale Nessun dato Partecipanti (6) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto AGRICULTURAL UNIVERSITY OF WAGENINGEN Paesi Bassi Contributo UE Nessun dato Indirizzo POSTBUS 9101 6700 HB WAGENINGEN Mostra sulla mappa Costo totale Nessun dato INIA Spagna Contributo UE Nessun dato Indirizzo APARTADO DE CORREOS 8111 28040 VALDEOLMOS Mostra sulla mappa Costo totale Nessun dato UNIVERSITE DE LIEGE Belgio Contributo UE Nessun dato Indirizzo PLACE DU 20-AOUT 7 4000 LIEGE Mostra sulla mappa Costo totale Nessun dato UNIVERSITY OF ABERDEEN Regno Unito Contributo UE Nessun dato Indirizzo ST. MACHAR DRIVE 23 AB2 IRY ABERDEEN Mostra sulla mappa Costo totale Nessun dato UNIVERSITY OF UPPSALA Svezia Contributo UE Nessun dato Indirizzo P.O. BOX 582 751 23 UPPSALA Mostra sulla mappa Costo totale Nessun dato Université de Paris VI (Université Pierre et Marie Curie) Francia Contributo UE Nessun dato Indirizzo 9 QUAI SAINT BERNARD 75230 Paris Mostra sulla mappa Costo totale Nessun dato
