Cracking the epitranscriptome

Publications

Peer reviewed articles (10)

Quantitative nucleotide resolution profiling of RNA cytidine acetylation by ac4C-seq

Author(s): Supuni Thalalla Gamage, Aldema Sas-Chen, Schraga Schwartz, Jordan L. Meier
Published in: Nature Protocols, 16/4, 2021, Page(s) 2286-2307, ISSN 1754-2189
Publisher: Nature Publishing Group
DOI: 10.1038/s41596-021-00501-9

Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution.

Author(s): David Dierks, Miguel Angel Garcia-Campos, Anna Uzonyi, Modi Safra, Sarit Edelheit, Alice Rossi, Theodora Sideri, Radhika A. Varier, Alexander Brandis, Yonatan Stelzer, Folkert van Werven, Ruth Scherz-Shouval & Schraga Schwartz
Published in: Nature Methods, 2021, ISSN 1548-7105
Publisher: Nature Methods
DOI: 10.1038/s41592-021-01242-z

The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution

Author(s): Modi Safra, Aldema Sas-Chen, Ronit Nir, Roni Winkler, Aharon Nachshon, Dan Bar-Yaacov, Matthias Erlacher, Walter Rossmanith, Noam Stern-Ginossar, Schraga Schwartz
Published in: Nature, 2017, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature24456

TRUB1 is the predominant pseudouridine synthase acting on mammalian mRNA via a predictable and conserved code

Author(s): Modi Safra, Ronit Nir, Daneyal Farouq, Ilya Vainberg Slutskin, Schraga Schwartz
Published in: Genome Research, 27/3, 2017, Page(s) 393-406, ISSN 1088-9051
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gr.207613.116

Variants in PUS7 Cause Intellectual Disability with Speech Delay, Microcephaly, Short Stature, and Aggressive Behavior

Author(s): Arjan P.M. de Brouwer, Rami Abou Jamra, Nadine Körtel, Clara Soyris, Daniel L. Polla, Modi Safra, Avia Zisso, Christopher A. Powell, Pedro Rebelo-Guiomar, Nadja Dinges, Violeta Morin, Michael Stock, Mureed Hussain, Mohsin Shahzad, Saima Riazuddin, Zubair M. Ahmed, Rolph Pfundt, Franziska Schwarz, Lonneke de Boer, André Reis, Detilina Grozeva, F. Lucy Raymond, Sheikh Riazuddin, David A. Koolen, M
Published in: The American Journal of Human Genetics, 103/6, 2018, Page(s) 1045-1052, ISSN 0002-9297
Publisher: University of Chicago Press
DOI: 10.1016/j.ajhg.2018.10.026

m6A modification controls the innate immune response to infection by targeting type I interferons

Author(s): Roni Winkler, Ella Gillis, Lior Lasman, Modi Safra, Shay Geula, Clara Soyris, Aharon Nachshon, Julie Tai-Schmiedel, Nehemya Friedman, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Michal Mandelboim, Jacob H. Hanna, Schraga Schwartz, Noam Stern-Ginossar
Published in: Nature Immunology, 20/2, 2019, Page(s) 173-182, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-018-0275-z

Context-dependent functional compensation between Ythdf m6A reader proteins

Author(s): Lior Lasman, Vladislav Krupalnik, Shay Geula, Mirie Zerbib, Sergey Viukov, Nofar Mor, Alejandro Aguilera Castrejon, Orel Mizrahi, Sathe Shashank, Aharon Nachshon, Dan Schneir, Stefan Aigner, Archana Shankar, Jasmine Mueller, Noam Stern-Ginossar, Gene W Yeo, Noa Novershtern, Jacob H Hanna
Published in: Genes and Development, Vol.34 (19-20), 2020, Page(s) 1373-1391, ISSN 0890-9369
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/2020.06.03.131441

Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping

Author(s): Aldema Sas-Chen, Justin M. Thomas, Donna Matzov, Masato Taoka, Kellie D. Nance, Ronit Nir, Keri M. Bryson, Ran Shachar, Geraldy L. S. Liman, Brett W. Burkhart, Supuni Thalalla Gamage, Yuko Nobe, Chloe A. Briney, Michaella J. Levy, Ryan T. Fuchs, G. Brett Robb, Jesse Hartmann, Sunny Sharma, Qishan Lin, Laurence Florens, Michael P. Washburn, Toshiaki Isobe, Thomas J. Santangelo, Moran Shalev-Benami,
Published in: Nature, 583/7817, 2020, Page(s) 638-643, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-020-2418-2

Deciphering the “m6A Code” via Antibody-Independent Quantitative Profiling

Author(s): Miguel Angel Garcia-Campos, Sarit Edelheit, Ursula Toth, Modi Safra, Ran Shachar, Sergey Viukov, Roni Winkler, Ronit Nir, Lior Lasman, Alexander Brandis, Jacob H. Hanna, Walter Rossmanith, Schraga Schwartz
Published in: Cell, 178/3, 2019, Page(s) 731-747.e16, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.06.013

m 1 A within cytoplasmic mRNAs at single nucleotide resolution: a reconciled transcriptome-wide map

Author(s): Schraga Schwartz
Published in: RNA, 24/11, 2018, Page(s) 1427-1436, ISSN 1355-8382
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1261/rna.067348.118