Projektbeschreibung
Die Rolle des Gehirns bei der Traumerzeugung
Träume sind zwar nur eine Phantasie, doch sie kommen uns sehr real vor, da unsere Gehirne für ihre Erzeugung zuständig sind. Das EU-finanzierte Projekt Dreamscape versucht, Antworten zur Rolle des Gehirns bei der Traumerzeugung zu finden. Es wird die elektroenzephalographischen Potenziale untersuchen, die im Schlaf und Wachzustand aufkommen, um aufzuzeigen, ob und warum diese Potenziale im Gehirn Träume erzeugen. Um die gewünschten Ergebnisse zu erhalten, wird Dreamscape eine Kombination innovativer experimenteller Ansätze verwenden, darunter pharmakologische Manipulationen und Bewegungsanalysen. Die Erkenntnisse werden unser Verständnis davon, wie und warum wir Träumen, ausweiten. Sie werden die Gebiete der Neurowissenschaft, Neuropsychiatrie und des Bewusstseins voranbringen und möglicherweise praktische Lösungen für Menschen mit Schlafstörungen hervorbringen.
Ziel
Why and how do we dream? Although this question has fascinated humankind since the earliest ages, it remains largely unanswered. Each night, when we fall asleep, we progressively disengage from the external world until we cease to perceive it and to act upon it. Despite this sensorimotor disconnection, in our dreams we perceive and act, and although we do so in a purely imaginary world, our experiences bear so much resemblance with the real world that we almost invariably take them for real. How does the brain create such a real-world analogue, and why? Based on my previous work, in which I identified a neural signature of dreaming, I propose to answer this question by studying a set of electroencephalographic (EEG) potentials, which not only occur spontaneously during sleep, but in a similar form also during wakefulness, as part of reactions to unexpected environmental stimuli. The overarching objective of this proposal is to understand the precise role of these brain potentials in the generation of dreams. Specifically, I will 1) provide a systematic characterization of these potentials in the sleeping and waking brain, 2) clarify their relation to arousal systems, 3) assess how they relate to sensory and motor features of dreams and 4) manipulate them to causally affect dreams. To achieve these aims, I will employ a unique combination of cutting-edge experimental approaches, including 256-channel-high-density EEG sleep recordings combined with controlled sensory stimulations, serial awakening paradigms, pharmacological manipulations, closed-loop acoustic slow wave modulation and movement analyses in neurological patients who act out their dreams. These projects will contribute to the basic understanding of how and why we dream, with implications for the fields of consciousness, neuroscience and neuropsychiatry. They will also provide technological and pharmacological tools to manipulate sleep and dreams, with clinical relevance for patients with sleep disorders.
Wissenschaftliches Gebiet
Schlüsselbegriffe
Programm/Programme
- HORIZON.1.1 - European Research Council (ERC) Main Programme
Thema/Themen
Finanzierungsplan
HORIZON-ERC - HORIZON ERC GrantsGastgebende Einrichtung
1011 JV AMSTERDAM
Niederlande