Bacteriocins from interbacterial warfare as antibiotic alternative

Informazioni relative al progetto

BACtheWINNER

ID dell’accordo di sovvenzione: 101054719

DOI

10.3030/101054719

Data della firma CE 1 Dicembre 2022

Data di avvio 1 Aprile 2023

Data di completamento 31 Marzo 2028

Finanziato da

• European Research Council (ERC)

Costo totale

€ 2 500 000,00

Contributo UE

€ 2 500 000,00

Coordinato da

UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (23)

Anionic liposome formulation for oral delivery of thuricin CD, a potential antimicrobial peptide therapeutic.

Autori: Viera Herrera C, O'Connor PM, Ratrey P, Paul Ross R, Hill C, Hudson SP.
Pubblicato in: International Journal of Pharmaceutics, 2024, ISSN 1873-3476
Editore: Elsevier
DOI: 10.1016/j.ijpharm.2024.123918

Promiscuous, persistent and problematic: insights into current enterococcal genomics to guide therapeutic strategy

Autori: Hourigan D, Stefanovic E, Hill C, Ross RP.
Pubblicato in: BMC Microbiology, 2024, ISSN 1471-2180
Editore: Springer Nature
DOI: 10.1186/s12866-024-03243-2

The Marine Fish Gut Microbiome as a Source of Novel Bacteriocins

Autori: Uniacke-Lowe S, Stanton C, Hill C, Ross RP.
Pubblicato in: Microorganisms, 2024, ISSN 2076-2607
Editore: MDPI
DOI: 10.3390/microorganisms12071346

Bacteriocin diversity, function, discovery and application as antimicrobials.

Autori: Sugrue I, Ross RP, Hill C.
Pubblicato in: Nature Reviews Microbiology, 2024, ISSN 1740-1534
Editore: Springer Nature
DOI: 10.1038/s41579-024-01045-x

Interplay between inflammatory bowel disease therapeutics and the gut microbiome reveals opportunities for novel treatment approaches

Autori: O’ Reilly C, Mills S, Rea MC, Lavelle A, Ghosh S, Hill C, Ross RP
Pubblicato in: Microbiome Research Reports, 2023, ISSN 2771-5965
Editore: OAE Publishing
DOI: 10.20517/mrr.2023.41

Raffinocyclicin is a novel plasmid-encoded circular bacteriocin produced by Lactococcus raffinolactis with broad-spectrum activity against many gram-positive food pathogens

Autori: Miceli de Farias F, O’ Connor PM, Buttimer C, Kamilari E, Soria MC, Johnson CN, Deliephan A, Hill D, Fursenko O, Wiese J, Draper LA, Stanton C, Hill C, Ross RP
Pubblicato in: Applied and Environmental Microbiology, 2024, ISSN 1098-5336
Editore: American Society for Microbiology
DOI: 10.1128/aem.00809-24

Scientific Reports

Autori: Felipe Miceli de Farias; Maria Cecilia Soria; Paula M. O’Connor; Xiaohui Huang; Colin Buttimer; Eleni Kamilari; Aiswariya Deliephan; Daragh Hill; Oxana Fursenko; Jonathan Wiese; Lorraine Draper; Catherine Stanton; Colin Hill; R. Paul Ross
Pubblicato in: Scientific Reports, 2025, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/S41598-025-89450-X

Impact of glyphosate (RoundupTM) on the composition and functionality of the gut microbiome

Autori: Walsh L, Hill C, Ross RP.
Pubblicato in: Gut Microbes, 2023, ISSN 1949-0984
Editore: Taylor and Francis Online
DOI: 10.1080/19490976.2023.2263935

Comparison of fidaxomicin, thuricin CD, vancomycin and nisin highlights the narrow spectrum nature of thuricin CD

Autori: Walsh L, Lavelle A, O'Connor PM, Hill C, Ross RP.
Pubblicato in: Gut Microbes, 2024, ISSN 1949-0984
Editore: Taylor and Francis Group
DOI: 10.1080/19490976.2024.2342583

Production, composition and nutritional properties of organic milk: A critical review.

Autori: Linehan K, Patangia DV, Ross RP, Stanton C.
Pubblicato in: Foods, 2024, ISSN 2304-8158
Editore: MDPI
DOI: 10.3390/foods13040550

Impact of bacteriocin-producing strains on bacterial community composition in a simplified human intestinal microbiota

Autori: Ríos Colombo NS, Perez-Ibarreche M, Draper LA, O’Connor PM, Field D, Ross RP and Hill C.
Pubblicato in: Frontiers in Microbiology, 2023, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2023.1290697

Winogradskyella bathintestinalis sp. nov., isolated from the intestine of the deep-sea loosejaw dragonfish, Malacosteus niger.

Autori: Uniacke-Lowe S, Johnson CN, Stanton C, Hill C, Ross P.
Pubblicato in: International Journal of Systematic and Evolutionary Microbiology, Numero VOL 73 (10), 2023, ISSN 1466-5034
Editore: Microbiology Society
DOI: 10.1099/ijsem.0.006135

Bioactivity screening and genomic analysis reveals deep-sea fish microbiome isolates as sources of novel antimicrobials.

Autori: Uniacke-Lowe S, Collins FWJ, Hill C, Ross RP.
Pubblicato in: Marine Drugs, 2023, ISSN 1660-3397
Editore: MDPI
DOI: 10.3390/md21080444

Somatic cell count as an indicator of subclinical mastitis and increased inflammatory response in asymptomatic lactating women

Autori: Angelopoulou A, Harris HMB, Warda AK, O’ Shea C-A, Lavelle A, Ryan A, Dempsey E, Stanton C, Ross RP.
Pubblicato in: Microbiology Spectrum, 2024, ISSN 2165-0497
Editore: American Society for Microbiology
DOI: 10.1128/spectrum.04051-23

Synergistic and off-target effects of bacteriocins in a simplified human intestinal microbiome: implications for <i>Clostridioides difficile</i> infection control

Autori: Natalia S. Ríos Colombo; R. Paul Ross; Colin Hill
Pubblicato in: Gut Microbes, 2025, ISSN 2162-402X
Editore: Taylor & Francis Online
DOI: 10.1080/19490976.2025.2451081

<i>Bacillus safensis</i> APC 4099 has broad-spectrum antimicrobial activity against both bacteria and fungi and produces several antimicrobial peptides, including the novel circular bacteriocin safencin E

Autori: E. Kamilari, P. M. O'Connor, F. Miceli de Farias, C. N. Johnson, C. Buttimer, A. Deliephan, D. Hill, O. Fursenko, J. Wiese, C. Stanton, C. Hill, R. P. Ross
Pubblicato in: Applied and Environmental Microbiology, 2024, ISSN 0099-2240
Editore: American Society for Microbiology
DOI: 10.1128/aem.01942-24

Early life exposure of infants to benzylpenicillin and gentamicin is associated with a persistent amplification of the gut resistome

Autori: Patangia DV, Grimaud G, O’ Shea C-A, Ryan CA, Dempsey E, Stanton C, Ross RP.
Pubblicato in: Microbiome, 2024, ISSN 2049-2618
Editore: BMC Part of Springer Nature
DOI: 10.1186/s40168-023-01732-6

Screening canine sources for novel antimicrobials reveals the circular broad-spectrum bacteriocin, caledonicin, produced by Staphylococcus caledonicus.

Autori: O’Connor M, O’Connor PM, Hourigan D, Murray E, de Farias FM, Field D, Hill C, Ross RP.
Pubblicato in: Frontiers in Microbiology, 2024, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2024.1470988

Planococcus notacanthi sp. nov., isolated from the skin of a deep-sea snub-nosed spiny eel.

Autori: Uniacke-Lowe S, Stanton C, Hill C, Ross P
Pubblicato in: International Journal of Systemic and Evolutionary Microbiology, 2024, ISSN 1466-5026
Editore: Microbiology Society
DOI: 10.1099/ijsem.0.006298

Discovery and synthesis of leaderless bacteriocins from the Actinomycetota

Autori: David Hourigan, Felipe Miceli de Farias, Paula M. O’Connor, Colin Hill, R. Paul Ross
Pubblicato in: Journal of Bacteriology, 2024, ISSN 0021-9193
Editore: American Society for Microbiology
DOI: 10.1128/jb.00298-24

Microbiota and Resistome Analysis of Colostrum and Milk from Dairy Cows Treated with and without Dry Cow Therapies

Autori: Patangia DV, Grimaud G, Linehan K, Ross RP, Stanton C.
Pubblicato in: Antibiotics, 2023, ISSN 2079-6382
Editore: MDPI
DOI: 10.3390/antibiotics12081315

Genome plasticity shapes the ecology and evolution of Phocaeicola dorei and Phocaeicola vulgatus.

Autori: Da Silva Morais E, Grimaud GM, Warda A, Stanton C, Ross P.
Pubblicato in: Scientific Reports, 2024, ISSN 2045-2322
Editore: Nature Portfolio
DOI: 10.1038/s41598-024-59148-7

Influence of age, socioeconomic status, and location on the infant gut resistome across populations

Autori: Patangia DV, Grimaud G, Wang S, Ross RP, Stanton C.
Pubblicato in: Gut Microbes, 2023, ISSN 1949-0984
Editore: Taylor and Francis Group
DOI: 10.1080/19490976.2023.2297837